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Active clinical trials for "Complex Regional Pain Syndromes"

Results 61-70 of 154

High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System

Chronic PainLow Back Pain2 more

Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.

Completed12 enrollment criteria

Clinical Evaluation of the Effects of Mirror Therapy in Patients With Complex Regional Pain Syndrome...

Complex Regional Pain Syndrome Type I

CRPS Type 1 can occur after traumas, surgical applications or central nervous system disorders. The triggering factor in CRPS type 1 is fracture in about half of the cases. Mirror therapy is an innovative treatment approach that is cheap, easy to administer and non-invasive. It is thought that this treatment may be complementary to other rehabilitation methods.Neurophysiologic effects of mirror therapy are noted in the brain, especially in the parietal region, cerebellum, basal ganglia and premotor cortex. Mirror therapy is also effective through the mirror neuron system. Mirror therapy triggers neuroplasticity by increasing the connection between neurons in the brain and thereby enhances communication between the motor and the sensory cortex. Recent studies have shown the positive effects of mirror therapy in patients with CRPS Type 1 disease. There are two randomized controlled trials showing the efficacy of mirror therapy in patients with CRPS Type 1 after stroke. Only one pilot study was performed in patients with CRPS Type 1 who were traumatic origin. There are no randomized controlled trials investigating the efficacy of mirror therapy in CRPS Type 1 patients who developed secondary to trauma in the literature. The purpose of this study is to investigate the clinical effects of mirror therapy applied in addition to routine rehabilitation program in patients with traumatic CRPS Type 1. The investigators hypothesized that adjunctive mirror therapy to classical rehabilitation program would result in better outcomes compared with the classical program only.

Completed14 enrollment criteria

Virtual Reality Guided Imagery for Chronic Pain

Complex Regional Pain SyndromesBack Pain

To assess treatment with an at-home Virtual Reality Guided Imagery (VR-GI) intervention, 36 patients with chronic pain (18 with chronic back pain, CBP, and 18 with complex regional pain syndrome, CRPS) will complete a 2-week intervention with at-home daily practice of VR-GI (n = 24) or audio-only GI (n = 12). Pre-post treatment measures of pain intensity, opioid use, functional outcomes, and mood will be collected. Intervention feasibility and patient satisfaction will be evaluated post-treatment via questionnaire and qualitative interview.

Completed10 enrollment criteria

A Study of the Effect of Lenalidamide on Complex Regional Pain Syndrome Type 1

Complex Regional Pain SyndromeType 1

The purpose of this study is to determine if lenalidomide is a safe and effective treatment for complex regional pain syndrome type 1 (CRPS).

Completed6 enrollment criteria

THORACIC MANIPULATION and COMPLEX REGIONAL PAIN SYNDROME

Complex Regional Pain Syndromes

To compare the effect of combined thoracic manipulation (TM) and traditional physical therapy treatment (TPT) versus TPT treatment alone on pain severity at rest and functional disability in patients with type 1 complex regional pain syndrome (CRPS I) post-upper limb trauma.

Completed2 enrollment criteria

Nitrous Oxide for the Treatment of Complex Regional Pain Syndrome

Complex Regional Pain Syndrome

Patients will then be randomized via a web-based randomization system Redcap Allocation will be stratified based on the presence of a pre-existing spinal cord stimulator to either the nitrous oxide study group or the oxygen control group. The nitrous oxide group will receive 50% nitrous oxide mixed with 50% oxygen, and the control group will receive 50% oxygen (oxygen plus air mixture). Both groups will undergo inhalation therapy for a duration of 2 hours via an FDA-approved mask breathing circuit. Vital signs (blood pressure, respiratory rate, heart rate) will be monitored every 30 minutes. Pulse oximetry monitoring will be continuous. Patients will be monitored for side effects including nausea, vomiting, desaturation, sedation, respiratory depression, and dizziness. Patients and other involved providers will be blinded to the treatment type.

Completed15 enrollment criteria

Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome

Amplified Musculoskeletal Pain SyndromeReflex Sympathetic Dystrophy1 more

A pilot randomized controlled trial to assess feasibility, acceptability and generate outcome domains for a future RCT testing the efficacy of immersive virtual reality on pain intensity in pediatric amplified musculoskeletal pain syndrome.

Completed8 enrollment criteria

A Clinical Trial of Mirror Treatment for Phantom Pain

Phantom Limb PainComplex Regional Pain Syndromes

A randomized controlled clinical to examine the effect of mirror therapy on phantom pain and residual limb pain in patients with traumatic transtibial amputations in Cambodia. The study will be conducted with a semi-crossover design using self-rated pain and function as the main result variables.

Completed7 enrollment criteria

Mirror Therapy in Complex Regional Pain Syndrome Type I

Complex Regional Pain Syndrome Type I

The aim is to evaluate the efficacy of Mirror Therapy on pain reduction and hand function in subjects with unilateral upper extremity Complex Regional Pain Syndrome Type I.

Completed5 enrollment criteria

Comparison of the Analgesic Effect Between the Motor Cortex Stimulation and the Trans-spinal Stimulation...

Algoneurodystrophy

The purpose of this study is to compare the analgesic effectiveness of two motor cortex neurostimulations (tDCS and rTMS) and the trans-spinal neurostimulation (tsDCS ) in the algoneurodystrophy.

Completed12 enrollment criteria
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