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Active clinical trials for "Pregnancy Complications"

Results 81-90 of 325

Prenatal Sonographic Prediction of Placental Histology and Function

Pregnancy Complications

The purpose of this two-phase observational study is to investigate the use of ultrasonography to predict placental pathology at the time of delivery.

Recruiting10 enrollment criteria

Birth Cohort Study of China Medical University

Twin; Complicating PregnancyAdvanced Maternal Age Pregnancy2 more

The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology. Data are collected regarding environmental factors, family and lifestyle, clinical experimental outcomes and imaging results of pregnant women and children from birth to 18 years old. Biological samples including blood and tissue samples are also collected from the children and their parents.

Recruiting5 enrollment criteria

Berlin-Brandenburg Pregnancy Cohort

PreeclampsiaPregnancy Complications1 more

This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

Recruiting5 enrollment criteria

Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During...

Sexually Transmitted InfectionAlcohol Use Complicating the Puerperium3 more

This proposed study is to test whether Health Check-up for Expectant Moms (HCEM), a computer-delivered screening and brief intervention (SBI) that simultaneously targets sexually transmitted infection (STI) risk and alcohol/drug use during pregnancy, reduces antenatal and postpartum risk more than an attention, time, and information matched control condition among pregnant women seeking prenatal care.

Active5 enrollment criteria

Predicting Dysglycemia in Individuals With Gestational Diabetes Immediately Postpartum Using Continuous...

Gestational DiabetesPrediabetes; Complicating Pregnancy5 more

Gestational diabetes is one of the most common medical disorders in pregnancy and is a major risk factor for the postpartum development of dysglycemia. Despite the high risk of developing dysglycemia, 50-80% of women with gestational diabetes are not receiving testing within a year postpartum. The investigators will conduct a prospective cohort study to examine the use of continuous glucose monitoring immediately postpartum to estimate the risk of maternal dysglycemia postpartum.

Recruiting14 enrollment criteria

The Microbiome in (Non-) Obese Pregnancy and Pregnancy Outcomes

ObesityMaternal2 more

This research aims to elucidate an underlying mechanism of maternal obesity induced pregnancy and longterm health complications for mothers and their offspring.

Recruiting12 enrollment criteria

Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy...

Pregnancy RelatedPregnancy Complications2 more

The Relugolix Pregnancy Registry is a prospective, observational cohort study designed to evaluate the association between relugolix-containing therapy exposure during pregnancy and subsequent maternal, fetal, and infant outcomes. Data will be collected from enrolled pregnant women and the healthcare providers (HCPs) involved in their care or the care of their infants, if applicable.

Recruiting12 enrollment criteria

COVID-19 and Pregnancy Outcomes

Coronavirus InfectionPregnancy Complications3 more

This is a multicenter prospective study that aims to investigate the clinical impact of SARS-CoV-2 infection in pregnant women, pregnancy outcomes and perinatal transmission.

Recruiting1 enrollment criteria

The Correlation Between Immunological Reaction of the Seminal Fluid in the Mother's Blood and Pregnancy...

PreeclampsiaPregnancy Complications3 more

It is known that if there isn't an efficient exposure to the paternal antigens before conception, there is an increased risk for the pre-eclampsia (PE) cascade and other pregnancy complications to take place. It is possible that maternal immune system that doesn't develop tolerance to the paternal antigens that the seminal fluid carries, doesn't developed an adequate immune tolerance to the trophoblast cells and due to that, they are being under greater attack during placentation. Thus, the cells don't go through a normal differentiation, don't perform normal pseudo-vasculogenesis and the PE cascade is more likely to be carried out. Both the maternal immune system and the paternal alloantigens have a role in the development of PE. Although the specific etiology remains unclear and can be only hypothesized. In this study the investigators aim is to try and prove that there is a difference in the immunological reactions to semen prior to conception and that these changes are related to PE and/or other obstetric complications. Hence the investigators aim to study the immune response to semen of women that will be exposed to the culprit semen for the first time compare to women that have been exposed to a culprit semen more than once previously (namely more than 1 insemination prior to the time of evaluation). After that, in a prospective cohort study the investigators would follow those women through their pregnancies and check for different pregnancy outcomes. In this manner, the investigators are hoping to create a screening tool that will help to predict pregnancy and fetal complications before conception related to maternal immune responses of paternal antigens.

Recruiting13 enrollment criteria

Database of Monochorionic Pregnancies

Monochorionic Diamniotic PlacentaMonochorial Monoamniotic Placenta3 more

The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.

Recruiting4 enrollment criteria
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