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Active clinical trials for "Compulsive Behavior"

Results 11-18 of 18

Acamprosate for Treatment of Compulsive Behaviors and Craving in Parkinson's Disease

Parkinson's Disease

The purpose of this study is to determine how many patients with Parkinson's disease have compulsive behaviors, and what types of behaviors they have. This study will also determine if acamprosate can be used to treat compulsive behaviors in Parkinson's disease patients.

Withdrawn12 enrollment criteria

Functional Magnetic Resonance Imaging (fMRI) Investigation Into Compulsivity in Anorexia

Anorexia Nervosa in Remission (Disorder)Compulsive Behavior

The investigators will examine compulsivity in those who have recovered from anorexia nervosa, using a multi-modal MRI study. The neural activation of key fronto-striatal areas will be explored using a task which examines set-shifting and reversal-learning, two key components of compulsivity. Additionally, the functional networks displayed during resting-state MRI will be examined between groups, as will the neurochemicals present (using Magnetic Resonance spectroscopy).

Completed13 enrollment criteria

Theta Burst Stimulation for Compulsive Behavior Non-invasive Brain Stimulation Study

Compulsive BehaviorObsessive-Compulsive Disorder

This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target brain region in two directions (up or down) and measure effects on compulsive behaviors and related measures. This work could ultimately lead to the ability to treat compulsions more effectively by targeting the regions of the brain that can help or hinder attempts to overcome compulsions.

Completed19 enrollment criteria

Glutathione Levels and Compulsivity

Anorexia NervosaCompulsive Behavior

The investigators will examine whether compulsivity in those who score above-average (but below clinical cut-off) on an eating disorder questionnaire can be altered by 9 days of N-acetyl cysteine (NAC). N-acetyl cysteine has been shown to be of some benefit in individuals with other compulsive disorders, such as trichotillomania and addiction, so this research investigates whether a short period of time taking N-acetyl cysteine changes compulsivity, measured using cognitive tasks and questionnaires.

Completed14 enrollment criteria

Personalized Inhibitory Control Training for Compulsive Behavior Change

OCD

Obsessive-compulsive disorder (OCD) is a severe mental illness characterized by repetitive behaviors that a person feels compelled to perform. It has been demonstrated that stimuli in the environment can trigger the compulsive urge, perpetuating the OCD cycle. The main goal of the current proposal, which is based on exciting pilot data, is to test a novel computerized training program to create an association between OCD-related stimuli, which typically trigger the compulsive urge, and the brain system responsible for stopping. The idea is that once this system is triggered, it will be easier for patients to stop the compulsive urge.

Unknown status11 enrollment criteria

Repetitive Behavior Disorders in People With Severe Mental Retardation

Mental RetardationStereotyped Behavior2 more

Repetitive behavior disorders are prevalent among people with severe mental retardation. These disorders can interfere significantly with an individual's daily functions. This trial is part of a long-term project that has studied the biologic basis of and possible treatments for repetitive behavior disorders. The trial will evaluate the effectiveness of two medications, a selective serotonin reuptake inhibitor (SSRI) and an atypical antipsychotic, in treating repetitive behavior disorders in people with mental retardation.

Unknown status13 enrollment criteria

Reducing Coercion in Norway (RECON)

Compulsion

There is considerable geographical variation in the rates of compulsion in psychiatric services within as well as between countries. Reducing the use of compulsion of patients with severe mental illness is an expressed policy aim, and also a demand from service user organisations. In Norway, municipalities hold responsibility for primary care and are therefore central to the delivery of services to people with severe mental illness. This indicates a potential for intervening at the municipal level to reduce the use of compulsion where it is high. The Reducing Coercion in Norway study (RECON) will, in collaboration with municipalities with high compulsion rates, develop a municipal-level intervention (Stage 1) that will be implemented in a cluster-RCT (Stage 2) to test if it has effect on compulsion rates.pulsion rates.

Unknown status6 enrollment criteria

Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features...

Romano-Ward SyndromeLong QT Syndrome2 more

The objectives of the study are to investigate if KCNQ1 mutation in Romano-Ward long QT patients can be associated with changes in insulin regulation and with psychological features of compulsivity, impulsivity and behavioural rigidity.

Unknown status8 enrollment criteria
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