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Active clinical trials for "Seizures"

Results 691-700 of 775

Quality of Life and Psychogenic Nonepileptic Seizures.

Psychogenic Nonepileptic Seizures (PNESs)

The goal of this study is to identify the prognostic factors of quality of life in patients with psychogenic non-epileptic seizures

Completed9 enrollment criteria

EEG in In-hospital Patients With Seizure or Altered Mental State

Status EpilepticusSeizure1 more

In Kuopio University Department of Clinical Neurophysiology there have been designed a fast EEG electrode, that is suitable for acute emergency use. It is easy to set up, records high quality EEG and can detect the most important EEG abnormalities comparable to conventional EEG. This study will address the clinical use of acute EEG with fast electrode set in in-hospital patients who have been consulted by Medical Emergency Team because of seizure or altered mental state of uncertain etiology. Patients are going to be treated in ICU and EEG monitoring will continue for 24 hours.

Completed3 enrollment criteria

Hypomagnesemia Associated With Proton-Pump Inhibitor Use

Proton Pump Inhibitor Adverse ReactionHypomagnesemia5 more

Use of proton pump inhibitors has been associated with hypomagnesemia. However, various case-control or prospective studies have found conflicting results with regards to proton pump inhibitors use and development of hypomagnesemia. Our aim was to evaluate the likelihood that proton pump inhibitors contributed to severe hypomagnesemia in a retrospective cohort of patients admitted with severe hypomagenesemia. We also aimed to look for risk factors leading to development of hypomagnesemia amongst users of proton pump inhibitors

Completed3 enrollment criteria

Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures

Febrile Seizure

Febrile seizures (FS) are the most common neurological disorder in chilhood. The etiology of FN is still the subject of numerous studies and it is known that it can depend on genetic predisposition.

Completed5 enrollment criteria

The Study of Pharmacokinetics of Levetiracetam in Patients Undergoing Intermittent Hemodialysis...

Seizures

Levetiracetam (LEV) is one of second-generation antiepileptic drugs that has been used to treat partial and generalized epilepsy. LEV is eliminated from the systemic circulation by renal excretion. Therefore, patients with renal impairment may experience a reduced drug excretion and increased adverse drug reactions. Moreover, patients with end-stage renal disease who need dialysis may experience low serum LEV concentration because of drug loss via dialysis. LEV loss via dialysis can cause low serum level of LEV that insufficient for seizure control. The present study was aimed to evaluate pharmacokinetics of LEV in patients undergoing 4 hour-intermittent hemodialysis (IHD). The results of the study may benefit to determine the appropriate LEV initial dose and supplemental dose for patients undergoing IHD.

Completed7 enrollment criteria

Biomarkers In Seizure To Predict Recurrence and Severe Outcomes

SeizuresS-100b Protein1 more

We study the hypothesis that combination of Proteine S100 beta and Copeptin within normal ranges can rule out seizure recurrences and severe outcome, and allow early discharge from the emergency department

Completed5 enrollment criteria

Prospective Research in Infants With Mild Encephalopathy

Hypoxic-Ischemic EncephalopathyBrain Injury1 more

A multicenter observational pilot study will be conducted to determine the natural history of infants with early diagnosis (≤ 6 hrs of age) of mild neonatal encephalopathy (NE) who are not qualified for therapeutic hypothermia. The intervention includes: neurologic examination by using modified Sarnat score at ≤ 6 hrs of age, 24 hrs and before discharge home, amplitude-integrated electroencephalography (aEEG) at 6 ± 3 hrs of age, brain MRI at before discharge home to 30 days of age and follow-up at 18-22 months of age. Primary outcome is the percentage of mild NE infants with evidence of brain injury defined by the presence of at least 1 abnormality of brain MRI, aEEG or neurologic examination in the neonatal period. Secondary outcome is the percentage of brain MRI, aEEG and neurological exam abnormalities, seizure, length of hospital stay, need of gavage feeds or gastrostomy at discharge home, death and long-term outcome.

Completed7 enrollment criteria

ANSeR- The Algorithm for Neonatal Seizure Recognition Study

Neonatal Seizures

A Multicentre Clinical Evaluation of a Decision Support Algorithm for Neonatal Seizure Detection: ANSeR

Completed4 enrollment criteria

Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study

Childhood Absence EpilepsyEpilepsy1 more

The purpose of our study is to identify gene(s) involved in the cause of childhood absence epilepsy (CAE).

Completed6 enrollment criteria

Validation Study of the Simplified Seizure Classification Algorithm

Epilepsy

An algorithm has been developed for simplified classification of epileptic seizures, in order to optimize choice of antiepileptic drugs. The objective of this study was to clinically validate the algorithm.

Completed2 enrollment criteria
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