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Active clinical trials for "Coronary Disease"

Results 2741-2750 of 2755

Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness

Myocardial Infarction

is to test the hypotheses that epicardial adipose tissue can be a marker of severity of coronary artery disease in myocardial infarction patients

Unknown status7 enrollment criteria

Influence of EPICardial Adipose Tissue in HEART Diseases: EPICHEART Study

Coronary Artery DiseaseCoronary Arteriosclerosis3 more

This translational study was designed to explore the association of the quantity and quality of epicardial adipose tissue (EAT) with coronary artery disease (CAD), left atrial remodeling and postoperative atrial fibrillation in a high cardiovascular disease-risk population. The investigators expect to identify new biochemical factors and biomarkers in the crosstalk between the epicardial adipocytes, coronary plaques and atrial cardiomyocytes that are involved in the pathogenesis of atherosclerosis and atrial fibrillation, respectively.

Unknown status9 enrollment criteria

IVUS VS CAG Guided PCI for Patients With LMB Lesion

Coronary Artery DiseaseLeft Main Coronary Artery Disease

To compare the 3 - year clinical follow - up results of patients with left main bifurcation lesions treated by intravascular ultrasound(IVUS) - guided and coronary angiography(CAG) - guided percutaneous coronary intervention(PCI), and to confirm the clinical benefits of optimizing interventional therapy of left main bifurcation lesions by intravascular ultrasound(IVUS).

Unknown status22 enrollment criteria

the Change of Cholesterol Efflux Capacity and Coronary Artery Disease in Real Clinical Practice...

Coronary Artery DiseaseCardiovascular Mortality2 more

The purpose of this study is to investigate the change of cholesterol efflux capacity in patients with coronary artery disease treated with secondary prevention drugs, and the correlation with the prognosis.

Unknown status2 enrollment criteria

Exercise Adherence in Home-based Cardiac Rehabilitation

Coronary Artery Disease

The study will investigate the influencing factors of exercise adherence of home-based cardiac rehabilitation in patients with coronary artery disease.

Unknown status6 enrollment criteria

Current Treatment Strategy of Patients With Multivessel Disease or Left Main Coronary Artery Disease...

Coronary Artery Disease

According to 2011 ACCF/AHA guideline and 2014 ESC/EACTS guideline, CABG surgery was recommended for three-vessel coronary artery disease and left main coronary artery disease in the patients with stable ischemic heart disease as class I. 2-VD with proximal left anterior descending artery stenosis was also indicated for CABG surgery as class I recommendation. However, many patients have been recommended for PCI by catheterization laboratory cardiologist; 46% and 93% in the only-CABG candidates and both CABG and PCI candidates, retrospectively, defined by previous ACC/AHA guideline. Although the discordance between real practice in catheterization laboratory and guideline would be adjusted by recently updated guideline. The revascularization strategy for patients with 3-VD/LMD in real practice have been getting toward more PCI and less CABG surgery. In this study, we will identify the rate of CABG candidates who were treated with PCI or medical treatment instead of CABG surgery in different from current guideline. We are also going to compare two treatment strategies CABG surgery vs. PCI with 2nd generation DES regarding clinical outcomes.

Unknown status10 enrollment criteria

Could Non-invasive Biochemical, Image or Physiological Index Predict Significant Coronary Arterial...

Coronary Heart Disease

To validate the capability of non-invasive bio-image tests in prediction of significant coronary stenosis of symptomatic adults.

Unknown status2 enrollment criteria

Beijing Percutaneous Coronary Intervention Registry

Coronary Heart Disease

The registry study is to obtain the state of the art of the percutaneous coronary intervention state treatment for coronary heart disease in Beijing area of P.R.China in a real world. The data are collected from 48 hospitals in Beijing area using an uploading system through internet.

Unknown status3 enrollment criteria

The Correlation of Heart Hemodynamic Status Between 320 Multidetector Computed Tomography, Echocardiography...

Coronary Artery Disease

With the advances in multidetector computed tomography (MDCT) technology, CT angiography (CTA) of the coronary arteries using 64-slice or dual-source CT systems has evolved into a robust, alternative, noninvasive imaging technique to rule out coronary artery disease (CAD). Reported sensitivities and specificities of coronary CTA can compete with those of catheter angiography. Because CT is the major source of ionizing radiation in medicine, dual isotope myocardial perfusion scintigraphy and coronary CTA 16-, 64-slice MDCT and DSCT scanners are associated with the highest amount of radiation dose. Recently, a new generation of MDCT machines with even more detector row (320) has become clinically available. The maximum detector width of 16 cm enables the entire heart to be examined in a single rotation and within a single heartbeat and is expected to substantially reduce artifacts from breathing and body motion. Due to high volume coverage, 320-slice CT machines are able to perform a nonspiral, ECG-gated examination of the heart within a single breath-hold. The purpose of this study was to investigate the correlation of hemodynamic status of 320 MDCT, echocardiography, and coronary catheterization in patients who suspected coronary artery disease.

Unknown status8 enrollment criteria

Role of Endothelial Function, Muscular Fitness and Metabolism in Functional Activity in Patients...

Chronic Heart FailureCoronary Disease1 more

Shortness of breath, fatigue, and exercise intolerance are clinical symptoms of chronic heart failure (CHF). Recent studies suggested that peripheral impairment was the major cause of clinical symptoms, and mechanism may be related to neuroendocrine impairment and vascular smooth muscle dysfunction. It results in increased peripheral resistance that may influence limb blood flow, muscle fitness and activities of daily.The purposes of this study are to compare muscular strength, endurance, and perfusion of quadriceps between CHF patients and healthy controls by isokinetic test and near-infrared spectroscopy (NIRS) and difference in activities of daily living to compare endothelium function between CHF patients and healthy control subjects the relationship between endothelium function, muscular strength, endurance, perfusion, and metabolism of quadriceps.

Unknown status5 enrollment criteria
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