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Active clinical trials for "Coronary Stenosis"

Results 231-240 of 273

320-slice Coronary Computed Tomography (CT) Angiography

Coronary Artery Stenosis

The primary aim of this study is to determine the potential utility of 320-slice volume-CT for obtaining adequate diagnostic accuracy while at the same time improving image quality compared with previous generations of CT scanners and simultaneously enabling a reduction in both radiation exposure and contrast agent amount required.

Completed7 enrollment criteria

Coronary Artery Stent Evaluation With 320-slice Computed Tomography - The CArS 320 Study

Coronary Artery Stenosis

The investigators aim at analyzing the diagnostic accuracy of 320-row CT for coronary stents.

Completed12 enrollment criteria

Pronostic Impact of Flow Fraction Reserve on Intermediate Stenoses

Coronary Stenosis

The intermediate coronary stenoses defined by a degree of stenosis from 40 to 70 % are frequent. The Flow Fraction Reserve (FFR), realized during coronarography, is an hemodynamic evaluation by the functional impact measuring the loss of load in upstream / approval of the stenosis inthe basal state and in situation of hyperemia led by adenosine. Further to the study FAME, the threshold of definition of the significant character of one Stenosis was fixed for a value of FFR = 0,80. However, the impact forecasts intermediate values badly known rest. We hypothetized that coronary stenosis associated with borderline values of FFR 0.81-0.85 were associated with a higher rate of clinical events than those with a FFR >0.85

Completed2 enrollment criteria

e-BioMatrix 6 Month DAPT France

Coronary Artery StenosesStable Angina3 more

Prospective, multi-center observational study to be conducted in up to 30 French interventional cardiology centers. The purpose of this observational study is to capture, in French Centers, clinical data of the BioMatrix Flex™ and BioMatrix NeoFlex™ Drug Eluting Coronary Stents System (Biolimus A9, BA9™-) in normal practice, in patients treated with 6-month DAPT, and to compare the outcomes to those of previous e-biomatrix registries with longer DAPT durations. The patients will be followed up for 2 years for data collection.

Completed11 enrollment criteria

Main Branch Versus Side Branch Ostial Lesion

Coronary Artery Stenosis

The investigators studied the relations between coronary angiography (CAG), intravascular ultrasound (IVUS) and fractional flow reserve (FFR) in coronary ostial lesions.

Completed17 enrollment criteria

Trial Comparison of Accuseal and Bovine Pericardial Patch During Endarterectomy

Coronary Stenosis

Carotid Endarterectomy (CEA), surgical removal of the blockage in the neck artery, is the accepted management of choice for significant blockage of the carotid artery. Previous studies showed improved perioperative outcomes and prevention of recurrent blockage by the use of the patch to close the surgical incision in the artery. The ideal patch reduces bleeding and prevents recurrent blockage.This is looking at long-term results toward improvement with the use Accuseal patch than Bovine Patch.

Completed2 enrollment criteria

Is Myocardial Revascularization Really Necessary in Patients With ≥50-70% Coronary Stenosis Undergoing...

Coronary Artery DiseaseHeart Valve Diseases

It is well documented in the literature that myocardial revascularization during valve surgery increases the risk of early mortality and morbidity. According to the most recent version of the European Guidelines, the possibility of myocardial revascularization via coronary artery bypass should be evaluated in patients with an indication for surgical treatment of heart valve disease but with coronary artery stenosis ≥ 50-70%. In this study, patients hospitalized for surgical heart valve disease, with occasional pre-operative finding of ≥ 50-70% coronary artery stenosis, without angina, are examined. After interdisciplinary discussion in the Heart Team, it was decided not to treat coronary artery disease during valve surgery. The aim is to evaluate the short and medium-term results of this "conscious omission".

Completed4 enrollment criteria

FFR and Inducible Myocardial Ischemia During Adenosine Stress Testing

Coronary Artery Stenosis

This is a prospective, single center study involving 150 patients with stable coronary artery disease undergoing coronary angiography for chest pain evaluation. The relationship between FFR values and inducible myocardial ischemia at the time of definite ischemia during adenosine stress testing will be investigated.

Unknown status15 enrollment criteria

Assessment of Lesion-Associated Myocardial Ischemia Based on Fusion Coronary CT Imaging

Myocardial IschemiaMyocardial Viability2 more

The aim of the Fused-Heart study is to investigate the impact of a coronary artery stenosis on myocardial function and viability, based on advanced fusion imaging techniques derived from CCTA. Moreover the study will investigate the correlation between morphology and composition of atheromatous plaques located in a coronary artery and myocardial ischemia in the territory irrigated by the same coronary artery.

Completed12 enrollment criteria

The Impact of Stent Deployment Techniques on Clinical Outcomes of Patient Treated With the CYPHER®...

Coronary Stenosis

1500 eligible patients will be treated with the commercially available CYPHER® sirolimus-eluting Bx Velocity™ stent. Patients will be followed to twelve months post-procedure, watching for patients that require a repeat procedure on the same diseased area of the coronary artery.

Completed10 enrollment criteria
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