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Active clinical trials for "Coronavirus Infections"

Results 771-780 of 855

Quality of Life and Physical Performance After Novel Coronavirus Infection (COVID-19);

Covid-19 (New Coronavirus) Infection

This study aims to observe the long-term health-related quality of life (HRQOL) and physical performance in individuals hospitalized due to a COVID-19 infection. Therefore, data is extracted from a study-site standard aftercare program which has been adjusted for this patient population. This comprehensive aftercare program includes education sessions and physical exercise. A second aim is to observe adherence and feasibility to the program and if indicated compare the clinical data and outcomes from patients following the program with patients denying to participate in guided exercise and education sessions. It is expected that patients hospitalized due to COVID-19 infection show a reduction in physical performance and HRQOL directly after discharge. The severity of illness is hypothesized to be associated with a reduction as well in HRQOL and physical performance after one-year post-discharge.

Unknown status15 enrollment criteria

Psychological Impact of the Corona Virus (SARS-CoV-2) and COVID-19 Pandemic in Individuals With...

Corona Virus InfectionPsychiatric Disorder1 more

The aim of this study is to measure current affective symptoms and psychological distress in individuals with severe mental illness during the COVID-19 pandemic using an online questionnaire survey. In addition, this study aims at identifying individual beliefs, sleep quality, attitudes concerning the virus, the adherence to the measures, believing processes, and coping strategies/resilience patterns referring to COVID-19 in different study centers.

Unknown status3 enrollment criteria

Cytokine and Eicosanoid Mediators in Coronavirus Disease 2019 (COVID-19)

COVID-19

This study is a prospective, single center, observational, cohort study of patients to (1) describe the kinetics and temporal relationship of changes in eicosanoid and cytokine mediators in patients with severe COVID-19 admitted to the hospital; and (2) correlate the dynamic changes in eicosanoid mediators with available patient clinical status, including measures of severity of illness, routine laboratory tests, and outcomes.

Unknown status10 enrollment criteria

Understanding COVID-19 Infection in Pregnant Women and Their Babies

Corona Virus InfectionPregnancy Related2 more

This national study will recruit expectant mothers with and without positive nasopharyngeal swabs for SARS-CoV-2, and aims to determine the seroepidemiology of SARS-CoV-2 amongst expectant mothers and their infants in the UK, the prevalence of vertical transmission of the virus or antibodies against the virus, and the effect, if any, on neonatal outcomes.

Unknown status4 enrollment criteria

Restoring Non-Emergent Cardiovascular Care in the Peri- COVID-19 Era

Corona Virus Infection

Pre-procedure and Short-Term COVID-19 Testing of Outpatients Undergoing Non-emergent Invasive Cardiovascular Procedures

Unknown status6 enrollment criteria

Evolution of Coronavirus Disease 2019 (COVID-19) Patients in Extremadura

Coronavirus Disease 2019

At the end of January 2020, the international community was informed of the presence of a new viral disease that started in Wuhan (China) and spread rapidly throughout the world. The identified virus belonged to the coronavirus family (SARS-CoV-2) and the disease was named COVID-19. Today there are more than 2 million people diagnosed in Spain and more than 40 thousand in Extremadura. The partial knowledge about the development, evolution of the affected citizenship and their prognosis both early and late makes it necessary to analyze in depth their global and particular characteristics. We will carry out a multicenter, observational, descriptive, cross-sectional and longitudinal study of patients diagnosed with SARS-CoV-2 virus infection in the Community of Extremadura to determine the effectiveness of drug treatments and the clinical and evolutionary characteristics of these patients and the different factors that may influence its evolution.

Unknown status3 enrollment criteria

Study for Novel Coronavirus Pneumonia (NCP)

Novel Coronavirus Pneumonia

To develop practical and effective clinical diagnosis and treatment schemes for the control of novel coronavirus pneumonia.

Unknown status2 enrollment criteria

Prevalence and Incidence of COVID-19 Infection in Patients With Chronic Plaque Psoriasis on Immunosuppressant...

Coronavirus Infection

This study will assess the prevalence and incidence of COVID-19 infection in patients with chronic plaque psoriasis on immunosuppressant therapy.

Unknown status22 enrollment criteria

Cerebral Bleeding in COVID-19 ARDS Patients on Veno-venous ECMO

Acute Respiratory Distress SyndromeExtracorporeal Membrane Oxygenation Complication1 more

Critically ill patients with severe acute respiratory distress syndrome (ARDS) sometimes require treatment with veno-venous extracorporeal membrane oxygenation (ECMO) to support gas exchange. To prevent clotting of the ECMO circuit, these patients need to be anticoagulated. This protective anticoagulation also leeds to an increased bleeding risk. Most critically ill COVID-19 patients suffer from an ARDS and some require ECMO support. However, the optimal strategy and targets for the anticoagulation of these patients remain uncertain. Studies have shown that COVID-19 is associated with endotheliopathy probably leading to procoagulatory effects. On the other hand, the incidence of bleeding complications associated with this endotheliopathy is not clear and remains to be elucidated. Anticoagulation of COVID-19 patients on ECMO thus poses a challenge for clinicians. The hypothesis of the current project is that COVID-19 patients with ARDS on ECMO exhibit a higher number of bleeding complications compared to historical control patients with non-COVID-19 ARDS requiring ECMO support.

Unknown status3 enrollment criteria

Haemoglobin Concentration on COVID-19

Corona Virus Infection

A rapid oxygen desaturation has observed in patients with COVID-19 which have seriously respiratory failure and most of them have intubated and connected to the mechanical ventilator. Finally, many of them have died during the process. ORF8 and superficial glycoproteins of a novel coronavirus bind to porphyrin on haemoglobin molecules and inhibit heme metabolism in an erythrocyte. However, it is not clarify the effects of the novel coronavirus on mean corpuscular volume (MCV), mean corpuscular of haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC).

Unknown status3 enrollment criteria
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