Influence of Skeletal Muscle Paralysis on Metabolism in Hypothermic Patients After Cardiac Arrest...
Critical IllnessCardiac ArrestThe purpose of this study is to evaluate the impact of muscle relaxing drugs on the energy rate during hypothermia after cardiac arrest.
Informing Decisions in Chronic Critical Illness: A Randomized Control Trial (RCT)
Chronic Critical IllnessProlonged Mechanical VentilationThe purpose of this study is to test a communication intervention to support family decision-making for patients with chronic critical illness.
Evaluation of Two Methods of Jejunal Placement of Enteral Feeding Tubes in Critically Ill Patients...
Critically IllIn patients with high gastric residual volumes jejunal feeding is recommended. Jejunal feeding tubes can be placed in different ways. The endoscopic technique yields a success rate between 90 and 98% for a correct jejunal placement. However, it requires endoscopic equipment and trained staff. In contrast in small uncontrolled trials different unguided techniques resulted in success rates up to 75%, only. In this prospective randomized trial the success rate of a correct jejunal placement with the endoscopic technique is compared with the unguided frictional technique. The investigators hypothesize that the success rate of the unguided frictional placement method will be lower than the success rate of the endoscopic method.
A Study in Critically Ill Patients Investigating Tolerability and Efficacy of Low-volume Pharmaconutrition...
Critical IllnessAdult2 moreThe aim of the study is to assess the efficacy and tolerability of the low-volume supplement. The investigators randomized critically ill patients to receive Intestamin plus Fresubin or Fresubin alone.
Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
Critical IllnessIntensive Care (ICU) Myopathy3 moreAn increasing number of patients survive critical illness and intensive care, but describe having impaired physical function several years after discharge as a consequence of extensive loss of muscle mass. Reasons for loss of muscle mass and physical function are multiple, but insufficient nutrition is likely to contribute. This randomised trial will investigate the effect of an optimised nutrition therapy during intensive care, on short term clinical outcome and physical quality of life. We hypothesise, that early nutritional therapy, directed towards patient-specific goals for energy and protein requirements, will improve both short- and long-term outcomes.
Safety and Dose Escalation Study of Zinc Supplementation in Critically Ill Children
Critical IllnessThe purpose of the study is 1) to determine whether administration of intravenous zinc to critically ill children is safe, and 2) to determine an appropriate dose of zinc supplementation.
Family Functioning and Child Behavior When a Sibling is Critically Ill
Child BehaviorThe goal of this study is to determine if there is a correlation between an efficacious family environment and sibling behavior in families with children who are critically ill.
Enhanced Recovery After Intensive Care (ERIC)
Critical IllnessThe primary objective of the multi-center stepped-wedge cluster-randomized controlled trial ERIC is to evaluate the effects of a multi-component telemedicine-based intervention delivered by the ICU on the adherence to quality indicators (QI) in intensive care medicine compared to usual care. Critically ill patients treated on the interventional condition receive daily tele-medical rounds during their ICU stay. Further secondary objectives are to demonstrate whether the intervention improves patient outcomes 3 and 6 months post ICU discharge, compared to usual care.
Evaluating the Effectiveness of an Electronic Medical Transfer Tool to Improve Communication During...
Critical IllnessTransitions of CareThe transfer of patients from the intensive care unit (ICU) to a medical or surgical hospital ward is a particularly high risk transfer that may expose patients to complications or adverse events if there are communication breakdowns between sending and receiving medical teams. Current dictation practice often falls short in producing optimal clinical documentation on patients being transferred from the ICU to the ward. The use of an electronic transfer of care tool to standardize communication may improve the quality of information exchanged between ICU and ward medical teams during ICU transfers, compared to dictation. This study will stagger implementation of a new electronic ICU medical transfer of care tool across four adult medical-surgical ICUs in one city. It is anticipated that the electronic ICU transfer tool will positively impact two inter-related goals: (1) improve the completeness and timeliness of clinical documentation on transfer, and (2) reduce the incidence of associated adverse patient clinical outcomes after transfer (e.g., adverse events, ICU readmission).
CPR Audiovisual Tool to Impact ICU Patients' Surrogate Anxiety Level.
Critical IllnessVideo or No Video to decrease HCPOA/LAR anxiety and increase knowledge as it pertains to CPR.