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Active clinical trials for "Ischemic Stroke"

Results 861-870 of 1835

Early Tracheostomy in Ventilated Stroke Patients

Ischemic StrokeIntracerebral Hemorrhage1 more

Patients with severe ischemic and hemorrhagic strokes, who require mechanical ventilation, have a particularly bad prognosis. If they require long-term ventilation, their orotracheal tube needs to be, like in any other intensive care patient, replaced by a shorter tracheal tube below the larynx. This so called tracheostomy might be associated with advantages such as less demand of narcotics and pain killers, less lesions in mouth and larynx, better mouth hygiene, safer airway, more patient comfort and earlier mobilisation. The best timepoint for tracheostomy in stroke, however, is not known. This study investigates the potential benefits of early tracheostomy in ventilated critically ill patients with ischemic or hemorrhagic stroke.

Completed17 enrollment criteria

Functional Magnetic Resonance Imaging (fMRI) and Robot-Assisted Practice of Activities of Daily...

HemiparesisIschemic Stroke1 more

The investigators will study motor recovery after robot-assisted therapy after stroke. A small clinical trial will be conducted to quantify the central nervous system changes associated with robotic or standard training, and identify trends across high and low responders in terms of patterns of change in cortical activity and type of white matter connectivity.The investigators hypothesize that robot training will lead to larger improvements as compared to standard occupational therapy. The investigators hypothesize that high responders to the robot training will have reduced compensatory activation in the bilateral area and will connectivity in the motor tracts.

Completed32 enrollment criteria

AXIS 2: AX200 for the Treatment of Ischemic Stroke

Acute Ischemic Stroke

The purpose of this study is to assess the efficacy of AX200 (filgrastim) in the treatment of acute ischemic stroke and to assess the safety and tolerability of AX200.

Completed18 enrollment criteria

Granulocyte-colony Stimulating Factor for Stem Cells Therapy for Acute Ischemic Stroke

Ischemic Stroke

The aim of the study is to investigate treatment with Leukostim (Filgrastim; granulocyte-colony stimulating factor; G-CSF) for acute ischemic stroke.

Completed16 enrollment criteria

Dose Escalation of Desmoteplase in Acute Ischemic Stroke (DEDAS)

Stroke

The purpose of this study was to explore trends in safety and efficacy, and to find the optimal dose for the subsequent phase III trial. The decision to initiate the phase III trial will depend on both safety (incidence of symptomatic intracranial hemorrhage) and efficacy (reperfusion measured by MRI and correlating with clinical outcome) profiles. The safety (incidence of symptomatic intracranial haemorrhage) and efficacy (reperfusion measured by MRI and correlating with clinical outcome) profiles gained from this study were the basis of planning the phase III.

Completed9 enrollment criteria

Safety/Feasibility of Autologous Mononuclear Bone Marrow Cells in Stroke Patients

Ischemic Stroke

The purpose of this research study is to find out if bone marrow treatment (bone marrow aspiration and infusion of stem cells) can be safely used in adults who have recently (within 24-72 hours)suffered an acute ischemic stroke.

Completed34 enrollment criteria

Multi MERCI (Mechanical Embolus Removal in Cerebral Ischemia [MERCI™])

Ischemic Stroke

The primary objectives of the Multi MERCI trial were: to evaluate the addition of the Merci L5 Retriever additionally permit use of the Merci Retrieval System in the setting of persistent clot following IV t-PA treatment (use in the 0-8 hour window for patients ineligible for IV t-PA was also permitted)

Completed14 enrollment criteria

AISTCM-Outcome Measurement of Acute Ischemic Stroke With Traditional Chinese Medicine

Cerebral Infarction

The purpose of this study is to determine whether Traditional Chinese Medicine (TCM) is able to improve the outcome of acute ischemic stroke and to observe its safety.

Completed17 enrollment criteria

Safety and Efficacy Study in Acute Ischaemic Stroke

Stroke

A Phase II study to evaluate the safety and efficacy of five dose levels of study drug in acute ischaemic stroke

Completed23 enrollment criteria

Randomized, Controlled Trial of Extended-Release Niacin (Niaspan®) to Augment Subacute Ischemic...

Ischemic Stroke

The purpose of this study is to determine the safety, tolerability, and to explore the possible benefit of extended-release niacin (Niaspan®) in attempting to improve the recovery of patients after ischemic stroke.

Completed32 enrollment criteria
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