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Active clinical trials for "Cystic Fibrosis"

Results 91-100 of 1428

FEED-Cystic Fibrosis (FEED-CF)

Cystic FibrosisCystic Fibrosis-related Diabetes

The goal of this study is to determine the extent to which excess dietary sugars serve as a precipitating factor in glucose intolerance in adults with cystic fibrosis (CF), a population at especially high risk for a unique form of diabetes (CF-related diabetes, CFRD) and with standard-of-care dietary recommendations (high-calorie, high-fat) that conflict with recommendations for other forms of diabetes. This trial will investigate if the typical high-sugar, high-fat CF diet plays a role in diabetes risk and visceral fat accumulation in people with CF. A total of 30 participants will get a low-added sugar, high-fat diet and the other 30 will get a standard CF diet with no sugar restrictions. Participants will be randomized to the diet group they are assigned. All foods will be provided for 8 weeks.

Recruiting19 enrollment criteria

ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2

Type 1 DiabetesType 2 Diabetes1 more

The purpose of this study is to determine if use of a nonmydriatic fundus camera using autonomous artificial intelligence software at the point of care increases the proportion of underserved youth with diabetes screened for diabetic retinopathy.

Recruiting4 enrollment criteria

Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF

Cystic Fibrosis

Cystic fibrosis has many health consequences. A reduction in the ability to perform exercise in patients with CF is related to greater death rates, steeper decline in lung function, and more frequent lung infections. However, the physiological mechanisms for this reduced exercise capacity are unknown. The investigators recently published the first evidence of systemic vascular dysfunction in patients with CF. Therefore, it is reasonable to suspect that the blood vessels are involved with exercise intolerance in CF. This study will look at how and if oxidative stress contributes to both artery dysfunction and exercise intolerance in CF.

Active19 enrollment criteria

Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision...

Cystic Fibrosis

The objective of this study is to evaluate the relevance of Porphyromonas as a biomarker predicting the risk of P. aeruginosa primocolonization in children form 0 to 18 years old with cystic fibrosis.

Recruiting10 enrollment criteria

Markers of Osteoporosis in Cystic Fibrosis

Cystic Fibrosis

Main Study Up to 100 subjects, both non-CF volunteers and Cystic Fibrosis (CF) patients, will participate in a single study visit that will include a DEXA scan, micro CT, and blood collection. Denosumab (Prolia) Sub study Approximately 10 adult subjects with CF who participated in the main study and have results indicating bone disease will receive treatment with Denosumab for up to 5 years. They will be asked to return annually for repeat DEXA scans, micro CT, and blood collection.

Recruiting9 enrollment criteria

Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis...

Cystic FibrosisLung Transplant; Complications

Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis

Recruiting6 enrollment criteria

Video Telehealth Exercise Training in Cystic Fibrosis

Cystic Fibrosis

The purpose of this research study is to begin an exercise program for patients with a cystic fibrosis (CF) exacerbation.

Recruiting3 enrollment criteria

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary...

AsthmaCOPD5 more

The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.

Recruiting15 enrollment criteria

Xenon-129 Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmonary...

Cystic FibrosisAsthma

Aim of this study is to evaluate image quality and reproducibility of Xenon-129 Magnetic Resonance Imaging (MRI) and to evaluate changes in lung structure and function in participants with cystic fibrosis (CF) and asthma compared to healthy controls using Xenon-129 MRI.

Recruiting17 enrollment criteria

Baby Detect : Genomic Newborn Screening

Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1134 more

Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions. With a simple blood test, rare genetic conditions can be easily detected, and the early start of transformative treatment will help avoid severe disabilities and increase the quality of life. Baby Detect Project is an innovative NBS program using a panel of target sequencing that aims to identify 126 treatable severe early onset genetic diseases at birth caused by 361 genes. The list of diseases has been established in close collaboration with the Paediatricians of the University Hospital in Liege. The investigators use dedicated dried blood spots collected between the first day and 28 days of life of babies, after a consent sign by parents.

Recruiting4 enrollment criteria
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