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Active clinical trials for "Deafness"

Results 601-610 of 613

SoundBite Hearing System 24 Month Multi Site Patient Use Study

Single Sided DeafnessConductive Hearing Loss

The objective of this multi-site observational study is to further assess the long-term patient use of the Sonitus SoundBite Hearing System. Information can be gained by assessing benefit for the subjects that were enrolled in the SoundBite Hearing System Long Term Multi Site Study (Protocol CLN006) for an additional 12 months.

Unknown status11 enrollment criteria

SoundBite Hearing System Long Term Multi Site Patient Use Study

Single Sided DeafnessConductive Hearing Loss

This study is designed to collect data about the SoundBite™ Hearing System to answer specific questions. The hearing system has been cleared for commercial distribution by the Food and Drug Administration (FDA). Sonitus hopes to learn from a larger group of users what features and settings of this device provide the best hearing ability for people diagnosed with Single Sided Deafness (SSD) or Conductive Hearing Loss (CHL).

Unknown status10 enrollment criteria

Neonatal Hearing Screening in Assiut Hospital

Neonatal Hearing Impairment

Hearing loss is one of the most common congenital anomalies. Early Intervention at or before 6 months of age allows a child with impaired hearing to develop normal speech and language.Auditory brainstem response , otoacoustic emissions testing have all been used in newborn hearing-screening programs

Unknown status5 enrollment criteria

Prevalence and Associations of Paediatric Chronic Suppurative Otitis Media and Hearing Impairment...

Chronic Suppurative Otitis MediaHearing Impairment

This community-based cross-sectional survey will estimate the frequency and risk factors of Chronic Suppurative Otitis Media and Hearing Impairment in Children ages 4-6 years in the Chikwawa District. These data will be useful for service planning, disease prevention efforts and to guide future research in this field.

Unknown status6 enrollment criteria

Video HIT in Sudden Sensorineural Hearing Loss

Sudden Sensorineural Hearing Loss

The function of the vestibular system among patients with Sudden Sensori Neural Hearing Loss will be evaluted using the video Head Impulse Test

Unknown status7 enrollment criteria

Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome

SUSAC's SyndromeEncephalopathy2 more

SUSAC's Syndrome (SS) is characterized by the clinical triad of encephalopathy, hearing loss, and retinal artery branch occlusions. Since the first description of SS in 1979, hundreds of patients with SS, mostly young women, have been reported. However, comprehensive epidemiological, clinical and etiological features of SS have never been specifically addressed so far. The objective of this study is to characterize the epidemiological, clinical, and etiological features of SUSAC's Syndrome. In this aim, the investigators will constitute a national clinical-based cohort including all SS cases retrospectively reported in France since the last 20 years and all new cases prospectively observed. French Society of Neurology, Ophthalmology and Internal Medicine will be asked to collaborate. Every case will be reviewed by an expert comity of internists, neurologists and neuroradiologists to validate the diagnosis. The exhaustive and systematic analysis of each case will help to better define different aspects of the disease such as the incidence and prevalence, the clinical presentation, the diagnostic modalities and the impact of treatments. Diffusion tensor magnetic resonance imaging of the brain will be obtained to more carefully study the cerebral microvasculopathy of the disease. Serum, cerebrospinal fluid, and DNA samples from each patient will also be collected to study potential autoimmune, thrombotic and infectious markers.

Unknown status7 enrollment criteria

Exome Analysis in Hearing Impaired Patients

Hearing Impairment

Hearing impairment is the most frequent sensory deficit in humans and affects one newborn out of 500. The prevalence rises to 3,5/1000 in teenagers due to retarded forms. Most of hearing impairments (about two thirds) have a genetic origin, with recessive, dominant or X-linked mode of inheritance. Some rare forms can be linked to mitochondrial DNA. Molecular diagnosis (i.e. defining the molecular basis of the disease, genes and precise DNA variants) is essential for the follow-up of patients and families. The project intends to perform exome sequencing on 30 samples of families presenting with hearing impairment. Families have been included based on the genetic origin of the hearing impairment (familial cases) and the exclusion of the involvement of 74 known deafness genes. Exome sequencing (sequencing of the coding regions of all known genes, about 22,000) in these cases may underly new gene/disease relationships.

Unknown status2 enrollment criteria

Clinical Applications of Round Window Imaging Anatomy in Cochlear Implant Surgery

Sensorineural Hearing Loss (Disorder)

The purpose of this study is to measure the size of the round window niche and its relation to the mastoid segment of the facial nerve and the mastoid cortex, using high resolution computerized tomography of the temporal bone, in order to assess preoperatively what is the extent of obstruction of the round window membrane and whether there is a surgical possibility of round window approach in the insertion of electrode array into the cochlea

Unknown status8 enrollment criteria

The Accuracy of Automated Audiometry Application on Smart Phone to Screen Hearing Loss

Hearing Loss

The purpose of study is to determine the diagnostic value of Hearing test program on smart phone for detected patients who has hearing loss.

Unknown status3 enrollment criteria

Development and Clinical Application of Two New Genetic Deafness Gene Diagnostic Kit

Waardenburg SyndromeLarge Vestibular Aqueduct Syndrome

The purpose of this study is to develop and applicate two new genetic deafness gene diagnostic kit for Waardenburg syndrome and large vestibular aquduct syndrome.

Unknown status3 enrollment criteria
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