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Active clinical trials for "Venous Thrombosis"

Results 251-260 of 679

Oral Rivaroxaban in Children With Venous Thrombosis

Venous Thrombosis

The purpose of this study is to find out whether rivaroxaban is safe to use in children and how long it stays in the body. There will also be a check for bleeding and worsening of blood clots.

Completed12 enrollment criteria

Role of a Novel Exercise Program to Prevent Post-thrombotic Syndrome

Acute Deep Vein Thrombosis

Despite standard care, 25%-50% of patients with clots in the deep veins of the arms and legs progress to chronic post-clot problems resulting in significant disability, loss of productivity, and healthcare costs. Reverse flow in the veins from an organizing clot is the primary cause of post-clot problems. Veins with early clot breakdown have a lower incidence of reverse flow. The investigators have observed that clot breakdown is enhanced by increased blood flow and that moderate arm and leg exercise result in increased venous blood flow. Hence, the investigators predict that a supervised exercise program in patients with deep vein clots could increase leg vein blood flow, accelerate clot breakdown, and decrease the risk of post clot problems. The primary hypothesis is that increased blood flow across the clot (induced by supervised exercise) will increase clot breakdown and decrease severity of post clot problems. The investigators are conducting a randomized clinical trial of standard therapy compared to progressive exercise training in patients with leg deep vein clots.

Completed14 enrollment criteria

D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants...

Deep Vein ThrombosisPulmonary Embolism

The purpose of this study is to determine if the risk of recurrent venous thromboembolism (VTE) after stopping therapy is low and acceptable in patients with a first unprovoked proximal deep vein thrombosis (DVT) or pulmonary embolism (PE) who have completed 3 months of therapy and who have a negative D-dimer test on therapy and 1 month after stopping therapy.

Completed18 enrollment criteria

D-dimer to Establish Duration of Anticoagulation After Venous Thromboembolism

Deep Vein ThrombosisPulmonary Embolism

The optimal duration of oral anticoagulant treatment in patients with idiopathic venous thromboembolism is still uncertain. The present study addresses the possible role of the D-dimer test in assessing the need for continuation of anticoagulation.The study aims at assessing whether D-dimer assay may have a role in guiding the duration of anticoagulation in these patients

Completed17 enrollment criteria

PeriOperative ISchemic Evaluation-3 Trial

Perioperative BleedingVenous Thrombosis1 more

This study is a multicentre, international, randomized controlled trial of tranexamic acid (TXA) versus placebo and, using a partial factorial design, of a perioperative hypotension-avoidance versus hypertension-avoidance strategy.

Completed18 enrollment criteria

Deep Vein Thrombosis Treatment With the Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients...

Venous ThrombosisDeep Vein Thrombosis

This is a multicenter, cohort study evaluating an adapted rivaroxaban dose regimen in patients with acute, proximal deep-vein thrombosis (DVT) or acute pulmonary embolism (PE) who concomitantly use a strong cytochrome P450 isoenzyme 3A4 (CYP 3A4) inducer for the entire 3-month study duration.

Completed7 enrollment criteria

Prospective Assessment of the Deep Vein Thrombosis (DVT) in Hospitalized Obstetrics Patients

Venous ThrombosisPregnancy

The purpose of the study is to prospectively assess the prevalence of venous thrombosis in women hospitalized for Cesarean Section, vaginal delivery or extended antepartum hospitalization by using Compression ultrasound of the entire proximal venous system of the lower limb veins.

Active6 enrollment criteria

Nifedipine vs Placebo for Maintenance Tocolysis of Preterm Labor.

Obstetric LaborPremature1 more

Comparing nifedipine to placebo for the maintenance tocolysis of preterm labor

Completed2 enrollment criteria

Personalized Warfarin Dosing by Genomics and Computational Intelligence

Venous ThrombosisAtrial Fibrillation1 more

This study will create a computer program that can be used to help dose a drug called warfarin for the prevention of blood clotting. The study will collected specific information about those patients receiving this drug and use that information to create a computer program that will predict the effects of the drug. With this prediction program in place, the investigators can perform a series of "what if I gave this amount of drug" simulations to determine the best dose of drug for that patient. Once the computer programs are developed, the investigators will test the program in patients that actually need this drug. They will also include genetic information into the prediction since it has been shown that this information can affect how well the drug works. Patients will have this genetic information determined during this study.

Terminated4 enrollment criteria

Anticoagulation Length in Cancer Associated Thrombosis

CancerThrombosis3 more

This is a two year, multicentre, mixed methods feasibility study including a randomised controlled two-arm interventional trial, a nested qualitative study, focus groups and a United Kingdom (UK) wide survey exercise.

Terminated9 enrollment criteria
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