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Active clinical trials for "Intervertebral Disc Degeneration"

Results 351-360 of 415

Calculating the Volume of the Paravertebral Space

Vertebral Disc Degenerative Disease

Volume of the paravertebral spaces of the tharic and lumbar regions will be measured.

Completed2 enrollment criteria

Study Using the CervicalStim Device Following Cervical Fusion

Vertebral Cervical Fusion SyndromeDegenerative Disc Disease

This study examines the effect of adjunctive use of the CervicalStim bone growth stimulator on cervical fusion rate in high risk subjects who have undergone cervical fusion surgery. All participants will wear the bone growth stimulator every day for 4 hours/day for 6 months.

Completed19 enrollment criteria

Osteocel® Plus in Anterior Lumbar Interbody Fusion (ALIF)

Degenerative Disc DiseaseLumbar

This study is being conducted to determine the percentage of patients with solid spinal fusions after being treated with Osteocel Plus in an ALIF procedure. Due to the unique processing conditions, Osteocel Plus retains a high concentration of stem cells in conjunction with the allograft bone matrix, so it is hypothesized that the fusion rate with Osteocel Plus will be comparable to published data for autograft. The Osteocel product family has already been used in approximately 15,000 cases worldwide.

Completed19 enrollment criteria

A Prospective Non-concurrent Controlled Evaluation of Open and MAS® PLIF

Lumbar Degenerative Disc Disease

The study is a prospective non-concurrent controlled observational evaluation of short-term operative results. As such, study sites will capture perioperative (through 6-week postoperative follow-up) case data associated with 10 standard open PLIF (posterior lumbar interbody fusion) procedures. After this open experience, these same sites will capture the corresponding data from 10 subsequent cases where the MAS (Maximum Access Surgery) PLIF variant was performed. The data from both series of cases will be compiled to identify similarities and differences between the techniques.

Completed13 enrollment criteria

A Study Comparing Fusion Rates of Two Lumbar Fusion Procedures

PseudoarthrosisSpinal Stenosis2 more

The purpose of this study is to demonstrate the relative efficacy of two lumbar fusion procedures: transacral lumbar interbody fusion when used in conjunction with unilateral or bilateral posterior pedicle screw fixation as an adjunct to fusion, in comparison to transforaminal lumbar interbody fusion (TLIF) when used in conjunction with unilateral or bilateral supplemental screw fixation as an adjunct to fusion. Subject candidates are those who had previously required and received fusion at L4-L5-S1 where these were the only lumbar levels treated for pseudoarthrosis, spinal stenosis, spondylolisthesis, or degenerative disc disease (DDD).

Completed6 enrollment criteria

Facet Wedge Post Market Study

Chronic Low Back PainDegenerative Disc Disease2 more

A Multi-centre, Prospective, single-arm post market clinical follow up study (PMCF) of the FACET WEDGETM spinal system to assess outcomes in subjects with chronic low back pain due to Degenerative Disc Disease (DDD), facet joint disease and/or pseudo arthrosis post anterior instrumentation. The objective of this study is to assess outcomes following implantation of the FACET WEDGE spinal system when used to provide fixation of lumbar motion segments. The primary objective of this study is to determine the rate of re-operations at the index level(s). The secondary objectives of this study are to confirm the safety and performance of the device and to collect patient reported outcome data.

Completed19 enrollment criteria

Retrospective/Prospective Data Collection on the LDR ROIA Interbody Fusion Device With VerteBRIDGE...

Degenerative Disc Disease

The purpose of this combination retrospective and prospective post market study is to examine the short term safety and efficacy of the ROI-A® interbody fusion device with VerteBRIDGE® plates to treat single and two-level degenerative disc disease between L2 and S1, with a focus on fusion rates and patient outcomes.

Completed11 enrollment criteria

An ACDF Multi-Center Study Using ViviGen Cellular Bone Matrix

Cervical SpondylosisDegenerative Intervertebral Discs1 more

The purpose of this post-market study is to collect data on ViviGen and how its use affects fusion rates in the cervical spine when used as additional grafting material to fill the cervical spacer. The patient population of interest is patients who have already elected to undergo a 2-3 level ACDF surgical procedure using ViviGen, per standard of care.

Completed29 enrollment criteria

CARES Lumbar Artificial Disc Registry

Lumbar Degenerative Disc Disease

The purpose of the registry is to assess outcomes following treatment with lumbar total disc replacement (TDR) in patients outside the clinical trial setting.

Terminated5 enrollment criteria

A Clinical Trial Evaluating a Total Disc Replacement in Patients With Cervical Disc Disease

Cervical Disc Disease

This study will be a non-randomized trial consisting of patients with single level (C3 to C7) symptomatic cervical disc disease who have not previously received fusion surgery at the same level, and have failed to improve with conservative treatment for at least 6 weeks prior to enrollment, or who present with progressive neurological symptoms or signs in the face of conservative treatment.

Terminated37 enrollment criteria
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