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Active clinical trials for "Dermatitis"

Results 591-600 of 1499

A Phase 2 Study of CIM331 for Atopic Dermatitis Patients

Atopic Dermatitis

To assess the safety, tolerability and efficacy of CIM331, compared to placebo, in atopic dermatitis patients who are inadequately controlled by or intolerant to topical therapy

Completed12 enrollment criteria

Tofacitinib Ointment For Atopic Dermatitis (Atopic Eczema)

DermatitisAtopic

The study is being conducted to evaluate the efficacy, safety and tolerability of 2% tofacitinib ointment (20 mg/g) BID (twice daily) in subjects with mild to moderate atopic dermatitis compared to placebo (vehicle) BID for 4 weeks.

Completed7 enrollment criteria

Bleach Bath Treatment of Adults With Atopic Dermatitis

Atopic Dermatitis

This is pilot, mechanistic study to address whether bleach baths given to adult subjects with atopic dermatitis or eczema, who are colonized with the bacteria Staphylococcus aureus, will significantly alter their skin microbiome and in so doing improve their skin barrier, diminish expression of inflammatory proteins in the skin and improve itch. To answer these questions the investigators will perform a 3-month, pilot, investigator-initiated, single-center, open-label clinical study. This study will allow us to test the following hypothesis: 1) that bleach baths will normalize skin barrier function, 2) that bleach baths will diminish the local inflammatory response in the skin, and 3) that bleach baths will improve validated measures of itch (also called pruritus).

Completed7 enrollment criteria

The Effect of Bathing and Moisturizers on Skin Hydration in Atopic Dermatitis: an in Vivo Study...

DermatitisAtopic

The purpose of this study is to determine the hydration effect of various regimens of skin bathing and moisturizer application on atopic dermatitis

Completed10 enrollment criteria

Human Testing of an Over-the-Counter (OTC) Cream in Children With Eczema

Atopic Dermatitis

This three week study will be conducted to determine the safety and efficacy of an over-the-counter (OTC) cream in children with mild to moderate atopic dermatitis.

Completed11 enrollment criteria

Investigation of the Efficacy of 2.5% and 5% Cis-urocanic Acid in Patients With Moderate or Severe...

Atopic Dermatitis

The purpose of this study is to evaluate dose response, safety, tolerability and efficacy of 2.5% and 5% cis-UCA in comparison to placebo and active comparator in the treatment of adult patients with moderate or severe chronic atopic dermatitis.

Completed22 enrollment criteria

Safety and Tolerability of Dupilumab in Participants With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

The purpose of this study is to assess the safety and tolerability of repeated subcutaneous (SC) doses of Dupilumab in participants with moderate-to-severe atopic dermatitis (AD).

Completed19 enrollment criteria

Safety, Tolerability, and PK of AN2728 in Adolescents With Atopic Dermatitis

DermatitisAtopic

The purpose of this study is to investigate the safety, tolerability, and systemic exposure of AN2728 Topical Ointment, 2%, in subjects with atopic dermatitis.

Completed20 enrollment criteria

A Study Comparing the Efficacy of Two Topical Steroid Application Regimens in Pediatric Patients...

Atopic Dermatitis

The purpose of this study is to investigate the efficacy of two different corticosteroid ointment application regimens for the treatment of eczema (atopic dermatitis).

Completed9 enrollment criteria

Single Center Study Using Omalizumab in Subjects With Atopic Dermatitis

Atopic Dermatitis

A phase 1 single center study in which omalizumab is dosed normally (according to the product insert) in subjects with atopic dermatitis.

Completed23 enrollment criteria
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