An Evaluation of a Novel Glucose Sensing Technology in Type 2 Diabetes
Type 2 Diabetes MellitusTo evaluate the impact of the Abbott Sensor Based Glucose Monitoring System on glycaemic control (HbA1c) compared to Self Monitoring Blood Glucose (SMBG) testing using a randomised controlled study design in adults with Type 2 diabetes using insulin.
Cardiovascular Oscillations in Coronary Patients With and Without Type 2 Diabetes
Coronary Artery DiseaseDiabetes Mellitus1 moreCoronary artery disease (CAD) and diabetes mellitus (DM) may promote alterations in heart responses during exercise or postural maneuver. Thus, the purpose of this study is to observe the influence of different postures (supine, seated and standing) and different percentages (15, 30, 45 and 60%) of the maximum voluntary contraction (MVC) of handgrip in the responses of heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), cardiac output (CO), stroke volume (SV) and peripheral vascular resistance (PVR) in coronary patients with and without type 2 diabetes.
Continuous Glucose Monitoring Self-Monitored Blood Glucose Type 2 Therapy Matrix Definition
Diabetes MellitusType 21 moreThe purpose of this study is to use data from the Continuous Glucose Monitoring (CGM) device and your Self-Monitored Blood Glucose (SMBG) levels to determine the best times to test blood glucose levels using SMBG.
Observational Study on Effectiveness and Safety of Liraglutide in Subjects With Type 2 Diabetes...
DiabetesDiabetes Mellitus1 moreThe study is conducted in Europe. The aim of this observational study is to assess glycaemic control while using liraglutide under normal clinical practice conditions in Belgium.
Diet, Insulin Sensitivity And the Brain
ObesityDiabetes Mellitus Type 2Obesity and insulin resistance may be in part explained by an altered reward system with changes in the serotonin/dopamine system. These changes might be caused by changes in dietary habits, especially by an increased intake of liquid sugar and an increase in meal frequency. The investigators hypothesize that increasing meal frequency compared to increasing meal size and when consuming a hypercaloric high-sugar diet (HS) compared to a hypercaloric high-fat-high-sugar diet (HFHS) will result in a reduction in cerebral serotonin and dopamine transporters and in a more prominent increase in insulin resistance. In addition, the investigators hypothesize that the changes in insulin sensitivity will be independent of changes in abdominal (visceral) and liver fat and that changes in insulin sensitivity due to the dietary manipulation will co-occur with changes in insulin signaling pathways in peripheral fat and muscle tissue.
Point of Care HbA1c as a Screening Test for Type 2 Diabetes in First Nations
Type 2 DiabetesPurpose to estimate the prevalence of undiagnosed diabetes mellitus and pre-diabetes in a BC First Nation community to determine the utility of community based screening by examining how many positively screened people follow up with the recommended subsequent testing and family physician visit to determine if point-of-care HbA1c test (Ames/Bayer DCA 2000) correlates with the confirmatory fasting and 2 hour post challenge blood glucose tests. Hypothesis The Point-of-Care test will correlate well with the gold standard diagnostic tests and prove to be a useful tool for community-based screening. This test obviates the need for fasting and repeat glucose tolerance testing.
Observational, Safety Study of NovoNorm® (Repaglinide) and Insulin Analogue Combination Therapy...
DiabetesDiabetes Mellitus1 moreThis trial is conducted in Asia. The primary objective of this study is to evaluate the clinical safety profile during 26 weeks of NovoNorm® (repaglinide) and insulin analogue combination therapy in type 2 diabetes under normal clinical practice conditions in Korea while the secondary objective is to evaluate the safety and efficacy after 13 and 26 weeks of NovoNorm® and insulin analogue combination therapy in type 2 diabetes under normal clinical practice conditions in Korea.
Long-term Daily Use of Trazenta® Tablets in Patients With Type 2 Diabetes Mellitus
Diabetes MellitusType 2Study to investigate the safety and efficacy of long-term daily use of Trazenta® Tablets as monotherapy in patients with type 2 diabetes mellitus and to assess baseline characteristics of patients with type 2 diabetes mellitus starting Trazenta® Tablets or any other oral antidiabetic monotherapy (naïve or switched from prior therapy of different oral antidiabetic drug).
The Effects of Micronutrients in Combination With Usual Care in Type 2 Diabetes
Type 2 DiabetesThis study is evaluating the impact of antioxidant supplements on blood sugar control and cardiovascular risk factors in adults over the age of 50 with at 3 months of Type 2 diabetes. The investigators hypothesize that daily supplementation with a multiple micronutrient formulation containing dietary and endogenous antioxidants in combination with usual care will reduce markers of oxidative stress and inflammation in Type 2 diabetes.
French Observational Survey to Assess Hypoglycaemia in Insulin-treated Diabetic Patients
DiabetesDiabetes Mellitus3 moreThis non-interventional study is conducted in Europe. The study is both retrospective and prospective. The purpose of the study is to assess the frequency of hypoglycaemia (low blood glucose) in insulin-treated patients with type 1 and type 2 diabetes.