Efficacy of Metronidazole Prophylaxis Against Clostridium Difficile-Associated Diarrhea in High...
Clostridium Difficile DiarrheaThe purpose of this study is to test if metronidazole prophylaxis is effective in decreasing the incidence of hospital induced Clostridium Difficile diarrhea among patients at high risk for this infection.
A Phase 2 Pilot Study to Assess ASP7147 in Patients With Diarrhea Predominant Irritable Bowel Syndrome...
Diarrhea Predominant Irritable Bowel SyndromeThis trial will evaluate the effect of ASP7147 on daily abdominal pain due to IBS-D during 4 weeks of treatment. It will also evaluate safety and tolerability in patients with IBS-D over the 4-week treatment period.
Nitazoxanide for the Treatment of Prolonged Diarrhea in Children
DiarrheaThe purpose of this study was to determine the efficacy of nitazoxanide suspension compared to placebo in treating prolonged diarrhea in children.
Effect of Herbal Extract Granules Combined With Probiotics on Irritable Bowel Syndrome With Diarrhea...
Irritable Bowel SyndromeThe aims of this study are to investigate the effect of famous herbal formula extract and probiotics on irritable bowel syndrome with diarrhea, and to determine whether these two experimental items affect intestinal permeability and the composition of intestinal microbiota.
An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage...
Early Stage HER2+ Breast CancerAn Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients with Early-Stage HER2+ Breast Cancer Treated with Neratinib and Loperamide or other prophylactic measures.
Fresh, Frozen or Lyophilized Fecal Microbiota Transplantation for Multiple Recurrent C. Difficile...
Recurrent C. Difficile Associated DiarrheaThe objective of the study is to investigate the efficacy of fresh, frozen or lyophilized fecal microbiota transplantation (FMT) via colonoscopy in patients with recurrent C. difficile associated diarrhea (RCDAD). Frozen, lyophilized or fresh fecal microbiota transplantation (FMT) inoculum will be generated from well-screened healthy volunteer donors of ≥150 gram/sample. Delivery of FMT will be performed colonoscopically. Fecal samples from donors and recipients will be saved for later metagenomic studies to characterize the microbiome of the gut in patients before and after FMT.
Effects of Pectin Supplementation in Diarrhea-predominant Irritable Bowel Syndrome
Irritable Bowel SyndromeThe purpose of this study is to investigate the effect of pectin, a kind of soluble dietary fiber, on clinical symptoms, gut microbiota and the immune status in patients with diarrhea-predominant irritable bowel syndrome
Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants
Acute DiarrheaAcute GastroenteritisThe purpose of this study is to determine the effect of zinc in acute watery diarrhea in children. The investigators will evaluate the effect of product versus placebo.
Irritable Bowel Syndrome With Diarrhea (IBS-D) Rifaximin Re-Treatment Study
Irritable Bowel Syndrome With DiarrheaThis study will evaluate the effectiveness and safety of repeat treatment with rifaximin 550 mg three times a day in patients with IBS with diarrhea who respond to initial treatment of rifaximin 550 mg three times a day.
Llama Antibody, Rotavirus Diarrhoea, Children
Male Children6-24 Months Old With Rotaviral Diarrhoea1 moreThe investigators hypothesize that : oral administration of VHH batch 203027 will be safe and tolerable for healthy Bangladeshi humans of all age groups (Part I) effective in reducing severity of diarrhoea in children with proven rotavirus infection (Part II). This entry only covers Part II.