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Active clinical trials for "Acidosis, Renal Tubular"

Results 1-9 of 9

Extension Study in Primary Distal Renal Tubular Acidosis

AcidosisRenal Tubular

Open-label study involving longitudinal assessment of the continued safety, tolerability, and efficacy of ADV7103 in maintaining targeted serum bicarbonate levels, preventing metabolic acidosis, and preventing hypokalemia in the following groups of subjects with primary dRTA: subjects who participated in Study B23CS and were adherent to the protocol; subjects ≥ 6 months of age who are living in Europe and did not participate in Study B23CS; and infants younger than 6 months of age

Not yet recruiting27 enrollment criteria

National Registry of Rare Kidney Diseases

Adenine Phosphoribosyltransferase DeficiencyAH Amyloidosis85 more

The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research. The purpose of this research is to: Develop Clinical Guidelines for specific rare kidney diseases. These are written recommendations on how to diagnose and treat a medical condition. Audit treatments and outcomes. An audit makes checks to see if what should be done is being done and asks if it could be done better. Further the development of future treatments. Participants will be invited to participate on clinical trials and other studies. The registry has the capacity to feedback relevant information to patients and in conjunction with Patient Knows Best (Home - Patients Know Best), allows patients to provide information themselves, including their own reported quality of life and outcome measures.

Recruiting4 enrollment criteria

Study Evaluating Subjects With Distal Renal Tubular Acidosis

Distal Renal Tubular Acidosis

This is a phase 3, prospective, multicenter, randomized, double-blinded, placebo-controlled withdrawal study comparing the efficacy of ADV7103 versus placebo in preventing the development of metabolic acidosis defined by serum bicarbonate levels in pediatric (6 months to < 18 years of age) and adult (18 to 65 years of age) subjects with primary Distal Renal Tubular Acidosis (dRTA).

Not yet recruiting26 enrollment criteria

Use of Sodium Bicarbonate in Patients Treated With Topiramate

EpilepsyMetabolic Acidosis1 more

Effect of oral sodium bicarbonate therapy on renal tubular acidosis in epilepsy patients taking topiramate.

Unknown status3 enrollment criteria

A Study Of Mircera In Patients With Kidney Disease Who Are Not On Dialysis

Renal Tubular AcidosisDistal1 more

This open-label, non-randomized, retrospective-prospective, non-interventional study will evaluate the efficacy and safety of Mircera in patients with stage III-IV chronic kidney disease (CKD) not on dialysis. Patients will receive open-label treatment with Mircera for 12 months at a dose to be determined by the investigator.

Completed10 enrollment criteria

Renal Tubular Acidosis is Highly Prevalent in Critically Ill Patients

AcidosisRenal Tubular

The aim of this study was to investigate the prevalence, type, and possible risk factors of RTA in critically ill patients using a physical-chemical approach.

Completed5 enrollment criteria

Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal...

AcidosisRenal Tubular2 more

Purpose To compare the performance of the two currently employed urinary acidifications tests in stone formers, the furosemide/fludrocortisone and ammonium chloride loading test. To study the impact of polymorphisms in the genes ATP6V1B1, ATP6V0A4 and SLC4A1 on urinary acidification in stone formers.

Completed5 enrollment criteria

Incidence of Renal Tubular Acidosis in Nephrology Unit in Assiut University Childern Hospital

Renal Tubule Acidosis

Providing summarized information on the clinical and biochemical characteristics and types of renal tubular acidosis in children in Assiut University Childern Hospital.

Unknown status10 enrollment criteria

Renal Tubular Acidosis in Incident Renal Transplant Recipients

Renal Transplant Disorder

Metabolic acidosis is a common complication in incident renal transplant recipients. Protracted acidosis may be associated with osteoporosis, inflammation, negative protein balance and malnutrition, and last but not least may cause renal dysfunction. Preliminary data indicate an increased prevalence of nephrocalcinosis in renal transplant biopsies of incident patients presenting with metabolic acidosis. The present study aims (1)evaluate the prevalence and type of renal tubular acidosis (RTA) in incident renal transplant recipients and to identify clinical correlates and (2) to find associations between RTA, nephrolithiasis and nephrocalcinosis

Unknown status5 enrollment criteria
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