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Active clinical trials for "Drug-Related Side Effects and Adverse Reactions"

Results 371-374 of 374

A Pharmacogenomics Study of Simvastatin-Induced Adverse Drug Reaction

Simvastatin Adverse ReactionPharmacogenomics1 more

Adverse reactions of simvastatin are mostly slight and transient, however, the incidence of simvastatin-induced hepatic impairment and myopathy are obviously higher in Chinese population than other racial groups. There is still lack of research data in Chinese. In this study, we will investigate whether there are specific genotypes which may predict the incidence of simvastatin-induced hepatic impairment and myopathy in Chinese so as to provide a basis for developing guidelines on precise medication in simvastatin therapy apply to Chinese population.

Unknown status4 enrollment criteria

Clinical Analysis of Safety in Latent Tuberculosis Infection Prophylaxis Treatment

Adverse Reaction to Drug3HP

The treatment of latent TB with 3HP is an important issue for the prevention of active TB. However, significant proportion of subjects receiving 3HP had adverse reaction. The main purpose of this observation study is to identify subjects who have higher risk to develop adverse reaction. Clinical characteristics and biomarker will be used to predict adverse reaction.

Unknown status12 enrollment criteria

Neonatal Hypotonia Associated With in Utero Exposure to Antidepressant

Neonatal HypotoniaAntidepressant Drug Adverse Reaction1 more

To better characterize the neonatal hypotonia associated with in utero exposure to antidepressants, so far limited to clinical cases, we will perform an observational retrospective pharmacovigilance study, using two databases. First, disproportionality analysis in Vigibase®, the World Health Organization global database, will be perform between antidepressant drugs and neonatal hypotonia . Second, narratives from the French National Pharmacovigilance Database will be extracted.

Unknown status2 enrollment criteria

Severe Cutaneous Adverse Reactions in Thailand

Steven-Johnson SyndromeToxic Epidermal Necrolysis3 more

The multicenter registry of patients with severe cutaneous adverse reactions among tertiary medical institutes in Thailand to study clinical characteristics, etiologies, therapeutic outcomes, quality of life, and the values of in vitro drug allergy diagnosis for the confirmation of the causative drugs

Unknown status2 enrollment criteria
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