search

Active clinical trials for "Geographic Atrophy"

Results 51-60 of 126

EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

Dry Age-related Macular Degeneration

The purpose of this clinical study is to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age-related macular degeneration (AMD).

Terminated26 enrollment criteria

A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants...

Geographic Atrophy

This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Terminated7 enrollment criteria

A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants...

Geographic Atrophy

This study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Terminated9 enrollment criteria

CLG561 Proof-of-Concept Study as a Monotherapy and in Combination With LFG316 in Subjects With Geographic...

Geographic Atrophy

The purpose of this study is to evaluate the safety and efficacy of 12 (every 28 days) intravitreal (IVT) injections of CLG561 as a monotherapy and in combination with LFG316 as compared to sham in subjects with geographic atrophy.

Completed10 enrollment criteria

Study to Evaluate the Safety of Intravitreal APL-2 in Patients Diagnosed With Geographic Atrophy...

Geographic Atrophy

Safety Assessment of APL-2 in Patients with Geographic Atrophy

Completed45 enrollment criteria

A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)...

Geographic AtrophyMacular Degeneration

The objectives of this study are to evaluate the safety and efficacy of Zimura (avacincaptad pegol) intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)

Completed8 enrollment criteria

Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration...

Age Related Macular DegenerationMacular Degeneration1 more

The purpose of this Phase I/II study is to investigate the safety and preliminary efficacy of unilateral subretinal transplantation of HuCNS-SC cells in subjects with geographic atrophy secondary to age-related macular degeneration.

Completed16 enrollment criteria

A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degeneration

Age-related Macular Degeneration

The main purpose of this study to evaluate the safety and tolerability of CNTO 2476 administered subretinally (beneath the retina) using the iTrack Model 275 micro catheter in patients with visual acuity (acuteness or clearness of vision) impairment associated with the geographic atrophy (GA: partial or complete wasting away of retinal layer below the retina) manifestation of age-related macular degeneration (AMD: medical condition which usually affects older adults and results in a loss of vision in the center of the visual field [the macula] because of damage to the retina).

Completed8 enrollment criteria

Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic...

AtrophyGeographic

The purpose of this study is to determine the safety and efficacy of GSK933776 in the treatment of geographic atrophy secondary to age-related macular degeneration.

Completed14 enrollment criteria

Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular...

Geographic AtrophyDry Age Related Macular Degeneration

The purpose of this phase II study is to determine the efficacy of fenretinide in the treatment of geographic atrophy (GA) in subjects with the dry form of age-related macular degeneration (AMD).

Completed3 enrollment criteria
1...567...13

Need Help? Contact our team!


We'll reach out to this number within 24 hrs