EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005
Dry Age-related Macular DegenerationThe purpose of this clinical study is to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age-related macular degeneration (AMD).
A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants...
Geographic AtrophyThis study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).
A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants...
Geographic AtrophyThis study is a Phase III, double-masked, multicenter, randomized, sham injection-controlled study evaluating the efficacy and safety of lampalizumab administered by intravitreal injections in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).
CLG561 Proof-of-Concept Study as a Monotherapy and in Combination With LFG316 in Subjects With Geographic...
Geographic AtrophyThe purpose of this study is to evaluate the safety and efficacy of 12 (every 28 days) intravitreal (IVT) injections of CLG561 as a monotherapy and in combination with LFG316 as compared to sham in subjects with geographic atrophy.
Study to Evaluate the Safety of Intravitreal APL-2 in Patients Diagnosed With Geographic Atrophy...
Geographic AtrophySafety Assessment of APL-2 in Patients with Geographic Atrophy
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)...
Geographic AtrophyMacular DegenerationThe objectives of this study are to evaluate the safety and efficacy of Zimura (avacincaptad pegol) intravitreal administration in patients with geographic atrophy secondary to age-related macular degeneration (AMD)
Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration...
Age Related Macular DegenerationMacular Degeneration1 moreThe purpose of this Phase I/II study is to investigate the safety and preliminary efficacy of unilateral subretinal transplantation of HuCNS-SC cells in subjects with geographic atrophy secondary to age-related macular degeneration.
A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degeneration
Age-related Macular DegenerationThe main purpose of this study to evaluate the safety and tolerability of CNTO 2476 administered subretinally (beneath the retina) using the iTrack Model 275 micro catheter in patients with visual acuity (acuteness or clearness of vision) impairment associated with the geographic atrophy (GA: partial or complete wasting away of retinal layer below the retina) manifestation of age-related macular degeneration (AMD: medical condition which usually affects older adults and results in a loss of vision in the center of the visual field [the macula] because of damage to the retina).
Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic...
AtrophyGeographicThe purpose of this study is to determine the safety and efficacy of GSK933776 in the treatment of geographic atrophy secondary to age-related macular degeneration.
Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular...
Geographic AtrophyDry Age Related Macular DegenerationThe purpose of this phase II study is to determine the efficacy of fenretinide in the treatment of geographic atrophy (GA) in subjects with the dry form of age-related macular degeneration (AMD).