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Active clinical trials for "Dyslipidemias"

Results 191-200 of 883

Safety, Pharmacokinetic Study of RVX000222 in Healthy Subjects and Subjects With Low HDL Cholesterol...

DyslipidemiaAtherosclerosis2 more

The purpose of this study is to investigate an oral formulation of RVX000222 for safety, pharmacokinetic and efficacy in healthy subjects.

Completed13 enrollment criteria

Safety Study to Evaluate the Effects of Mild and Moderate Renal Impairment on the Pharmacokinetics...

DyslipidemiaRenal Insufficiency

Safety Study to Evaluate the Effects of Mild and Moderate Renal Impairment on the Pharmacokinetics of ABT-335 and Rosuvastatin When Administered Concomitantly

Completed4 enrollment criteria

Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin,...

Coronary Artery DiseaseCoronary Heart Disease1 more

The primary purpose of this study is to test the effect and safety of once daily ABT-335 on the thickness of the lining of the carotid artery (a blood vessel to the brain) in patients with abnormal blood lipids who have optimal levels of low density lipoprotein cholesterol ("bad cholesterol") after taking atorvastatin.

Completed6 enrollment criteria

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia...

Lipid MetabolismInborn Errors18 more

The purpose of this study is to evaluate the safety and efficacy of mipomersen (ISIS 301012) in subjects with homozygous familial hypercholesterolemia on lipid-lowering therapy. This study consisted of a 26-week treatment period and a 24-week post-treatment follow-up period. Following treatment and Week 28 evaluations, participants could elect to enroll in an open-label extension study (301012-CS6; NCT00694109). Participants who were not eligible or elected not to enroll in the open-label extension study or who discontinued during the 28-week treatment period were followed in this study for 24 weeks from administration of the last dose of study drug.

Completed5 enrollment criteria

TTA in Treatment of Diabetes and Dyslipidemia

Type 2 Diabetes MellitusDyslipidemia

The aim of the study is to evaluate the short-term effects of tetradecylthioacetic acid (TTA) on plasma lipids and glucose in male patients with type 2 diabetes mellitus and dyslipidemia

Completed7 enrollment criteria

IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin

Fredrickson Type IIa & Type IIb Dyslipidaemia

The purpose of this study is to assess the effects on the kidney of rosuvastatin and simvastatin in subjects with Fredrickson Type IIa & Type IIb Dyslipidaemia

Completed6 enrollment criteria

Open Label Study Evaluating The Use Of Combination Therapy Of Ezetimibe And Statins In Patients...

Lipid Metabolism Disorder

Gather additional efficacy and safety (pharmacovigilance) information in the usual daily care in patients with Dyslipidemia on ezetimibe under real conditions in Colombia associated with statins.

Completed10 enrollment criteria

Atorvastatin Study For The Treatment Of High Cholesterol In Patients From Thailand

Dyslipidemias

The purpose of this study is to evaluate the efficacy of atorvastatin in lowering cholesterol on patients from Thailand with high cholesterol.

Completed5 enrollment criteria

A Study Of Atorvastatin For The Treatment Of High Cholesterol In Patients At High Risk Of Coronary...

Dyslipidemias

A study of the long-term (1 year) effectiveness of atorvastatin to keep patients of high cardiovascular risk at the LDL cholesterol goal of <115 mg/dL

Completed4 enrollment criteria

Evaluate Safety and Efficacy of ABT-335 in Combination With Atorvastatin in Subjects With Multiple...

Mixed DyslipidemiaCoronary Heart Disease1 more

The purpose of this study is to compare the safety and efficacy of fenofibric acid (ABT-335) + atorvastatin combination therapy with ABT-335 and atorvastatin monotherapy in subjects with multiple abnormal lipid levels in the blood.

Completed5 enrollment criteria
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