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Active clinical trials for "Abortion, Spontaneous"

Results 111-120 of 276

Randomized Double-blind Controlled Trial of Use of Dydrogesterone in Threatened Miscarriage

Pregnancy

The aim of this study is to determine whether the dydrogesterone therapy is associated with reduction in miscarriage in women with first trimester threatened miscarriage. The hypothesis is that the dydrogesterone therapy will significantly reduce the risk of miscarriage in women with threatened miscarriage.

Completed12 enrollment criteria

ANXA5 M2 Haplotyping in IVF Patients and Embryos

InfertilityMiscarriage2 more

This study aims to characterize the association between history of pregnancy complications and M2 carrier status in IVF patients and the utility of M2 haplotype preimplantation genetic testing (PGT) in embryos produced by carrier couples. Participants in this study will be screened for the M2 variant. History of pregnancy complications and miscarriages will be studied in order to determine potential associations with M2 carrier-ship.

Active2 enrollment criteria

RPL: Interval to Live Birth and Adverse Perinatal Outcomes

AbortionSpontaneous5 more

This will be a retrospective observational cohort study utilizing the data from the British Columbia Perinatal Data Registry (BCPDR). The BCPDR is a provincially inclusive database that aggregates obstetrics and neonatal variables from all attended births in British Columbia. The primary objective of this study is to evaluate and contrast the average time interval from the first to second birth for patients with recurrent pregnancy loss compared to healthy controls. Secondarily, the investigators will calculate the cumulative live birth rate in the cohort of women with recurrent pregnancy loss who were </= 35 at age of first birth and delivered between the years 2000-2010. Finally, the investigators will compare the incidence of adverse perinatal outcomes for those with recurrent pregnancy loss and those without. The results of this study will be valuable for clinicians and patients as it will provide information for prognosis counselling. This will also help those desiring more than one child with long term family planning.

Active5 enrollment criteria

Treatment of Missed Miscarriage With TRUCLEAR Tissue Removal System, a Feasiblity Study

Miscarriage

the Aim of this study is to prospectively study the feasibility of evacuation of products of conception (POC) in missed miscarriages up to 10 weeks using the TRUCLEAR tissue removal system in order to achieve targeted treatment under direct vision of the POC and thus potentially reducing the risk of complications and intrauterine adhesions

Completed9 enrollment criteria

Group Interpersonal Psychotherapy for Treatment of Major Depressive Disorder Following Perinatal...

Major Depressive DisorderMiscarriage2 more

The purpose of this study is to conduct a randomized pilot trial in a sample of 60 women who meet criteria for Major Depressive Disorder (MDD) 1-18 months after a perinatal loss to demonstrate the feasibility of the proposed recruitment methods and research design, of the therapist training methods, and of delivering the adapted Interpersonal Psychotherapy group treatment. The investigators would like to examine preliminary evidence for the following hypotheses: Perinatal-loss specific IPT-G will be more acceptable to women who experience MDD following perinatal loss than will Coping with Depression (CWD). Perinatal-loss specific IPT-G will result in reduced time to remission from MDD and reduced depressive symptoms relative to CWD. Perinatal-loss specific IPT-G will result in increased social support and social functioning, reduced couple distress, and reduced grief relative to CWD.

Completed10 enrollment criteria

Medical Abortion With Single Daily Dose of Misoprostol

Miscarriage

Medical abortion using multiple vs single daily dose of misoprostol in first trimester miscarriage.

Completed17 enrollment criteria

Habitual Abortion Study: Oral Dydrogesterone Treatment During Pregnancy in Women With Recurrent...

Recurrent Miscarriage

The purpose of this clinical study is to demonstrate the shift from inflammatory cytokines to non-inflammatory cytokines in women suffering from habitual abortion treated with dydrogesterone (Duphaston).

Completed4 enrollment criteria

Oral Progesterone for Prevention of Miscarriage in Threatened Abortion

Threatened Abortion

This study evaluates the effectiveness of oral dydrogesterone in preventing miscarriage in threatened abortion. Half of participants will receive oral dydrogesterone, while the other half will receive oral placebo.

Completed10 enrollment criteria

Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia

AbortionHabitual

The prevalence of insulin resistance is increased in women with recurrent miscarriage compared with matched fertile controls,Insulin resistance (IR) in this syndrome is not only implicated toward early pregnancy loss (EPL) but also pathognomic for various obstetrical complications during pregnancy.An elevated free androgen index appears to be a prognostic factor for a subsequent miscarriage in women with recurrent miscarriage. There is insufficient evidence to evaluate the effect of metformin supplementation in pregnancy to prevent a miscarriage in women with recurrent miscarriage.

Withdrawn8 enrollment criteria

Timing of Initiation of LMWH Administration in Pregnant Women With APS

Recurrent MiscarriageAntiphospholipid Syndrome

Evaluation of the effect of altering the timing of initiation of low molecular weight heparin (LMWH) administration on the pregnancy outcomes in women with antiphospholipid syndrome (APS)

Completed5 enrollment criteria
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