Study of the Effect of the Drug Gabapentin on Postoperative Pain and Incidence of Postoperative...
ObesityMorbid2 moreThe purpose of this research study is to evaluate the drug gabapentin (Neurontin®) for its ability to reduce postoperative pain, the need for morphine-like pain medication, and the severity and frequency of postoperative nausea and vomiting in laparoscopic gastric bypass surgery patients.
Analgesic Effect of Preoperative Dexamethasone in Gynecological Laparotomies - a Dose-ranging Study...
Postoperative PainPostoperative Nausea and Vomiting1 moreThe objective of the study is to examine the effect of the addition of intravenous dexamethasone 1.5 hours prior to induction of anesthesia on the post-operative opioid consumption, pain scores, fatigue, and recovery in patients undergoing gynecological surgery with laparotomy under general anesthesia. This is a dose finding study with two different doses (0.1 mg/kg vs. 0.2 mg/kg) of dexamethasone to find out the optimal efficacious dose of dexamethasone with minimal side effects. Dexamethasone has anti-inflammatory, immunomodulatory, and analgesic effects; and is superior to placebo in providing post-operative pain control, lower analgesic consumption, prevention of postoperative nausea and vomiting, lesser post-operative fatigue, and better recovery profile. No dose response study has been done. The investigators hypothesize that a higher dose of dexamethasone may have an incremental beneficial effect.
Dronabinol Versus Placebo in Treatment and Prevention of Highly Active Anti-Retroviral Therapy (HAART)-Related...
Highly Active Antiretroviral Therapy (HAART)-Related Nausea and VomitingHIV InfectionsThe primary purpose of this study is to determine if dronabinol is effective in preventing or treating nausea caused by HAART (highly active anti-retroviral therapy) in HIV and AIDS patients
Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department
Nausea and VomitingThis study will compare the effect of prochlorperazine and ondansetron for the treatment of nausea and vomiting in the emergency department.
Exteriorized Versus In Situ Uterine Repair at Cesarean Delivery
VomitingNausea3 moreThis study was undertaken to compare the two techniques (exteriorized vs in situ) of uterine repair with respect to patient comfort, hemodynamic changes, surgical time and blood loss, in patients undergoing elective CD under a strictly standardized spinal anesthetic. We hypothesized that in situ uterine repair would be more comfortable for the patients.
Topiramate for the Prophylactic Treatment of Cyclic Vomiting Syndrome in Children
VomitingThe purpose of this study is to assess the effectiveness, tolerability and safety of oral topiramate for the preventative management of Cyclic Vomiting Syndrome. It is believed that topiramate will decrease the frequency, duration and severity of attacks experienced by children and adolescents with Cyclic Vomiting Syndrome.
Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients...
Multiple MyelomaThe primary purpose of this study is to explore the efficacy of three different dose schedules of palonosetron for the prevention of emesis over a 7-day study interval in multiple myeloma patients.
A Pilot Study of Dronabinol for Adult Patients With Primary Gliomas
Brain NeoplasmsNausea1 moreThis study seeks to define the tolerability and safety associated with the administration of Dronabinol in the treatment of adults with nausea, vomiting and appetite loss in patients with primary gliomas who are undergoing chemotherapy treatment. The study will also describe the effect of Dronabinol on the quality of life in terms of nausea, vomiting and anorexia in this patient group.
Olanzapine for Chemotherapy-induced Nausea and Vomiting Prophylaxis
Complete Response Rate to Chemotherapy-induced Nausea and Vomiting ProphylaxisTo investigate that olanzapine can reduced side effect about nausea and vomiting in women with gynecologic cancers receiving carboplatin-based regimen by using olanzapine and placebo
High-Dose Steroid for Hip Arthroplasty Patients Expected to Have Postoperative Pain
Postoperative PainPostoperative Nausea and Vomiting6 moreThe purpose of the Study is to test a higher dose of steroids(Dexamethasone) given just prior to surgery in the setting of Fast-Track Hip-surgery with Arthroplasty in a group of expected High Pain Responders and the effect on postoperative pain and postoperative inflammation.