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Active clinical trials for "Endometrial Hyperplasia"

Results 21-30 of 71

Patient-derived Tumor-like Cell Clusters Predict Progesterone Sensitivity in Patients With Early...

Endometrial Carcinoma Stage IAtypical Endometrial Hyperplasia

To construct a prediction model of progesterone sensitivity in patients with endometrial cancer treated with fertility preservation

Recruiting11 enrollment criteria

Metformin Plus Megestrol Acetate as a Fertility-sparing Treatment in Patients With Atypical Endometrial...

Atypical Endometrial Hyperplasia

To verify whether metformin could improve the effect of progestin as fertility-sparing treatment in patients with atypical endometrial hyperplasia(AEH).

Terminated16 enrollment criteria

Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia

High Grade Squamous Intraepithelial NeoplasiaStage 0 Uterine Corpus Cancer

This randomized phase II trial is studying how well megestrol works in treating patients with endometrial neoplasia or endometrial hyperplasia. Estrogen can cause the growth of endometrial cancer cells. Hormone therapy using megestrol may fight endometrial cancer by blocking the use of estrogen by the abnormal cells.

Terminated23 enrollment criteria

Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial...

Endometrial Hyperplasia

The investigators hypothesize that combined treatment with the GLP-1R agonist semaglutide 2.4 mg and levonorgestrel intrauterine device (LNG-IUD), compared to LNG-IUD alone, will result in improved likelihood of uterine preservation, sustained weight loss, improved endometrial and metabolomic response to progestin, and improved quality of life in premenopausal women with endometrial hyperplasia who desire uterine preservation.

Not yet recruiting27 enrollment criteria

Apoptotic Signaling Pathways in Rats With Endometrial Hyperplasia

Apoptotic Signal Pathways in Endometrial Hyperplasia

The purpose of the study is to determine apoptotic signaling pathways such as Survivin, Bcl-2, Bax, c-Myc and caspase-9 expression levels in rats model with iatrogenic endometrial hyperplasia after metformin and medroxyprogesterone acetate administration.

Completed2 enrollment criteria

MPA Versus Dydrogesterone for Management of Endometrial Hyperplasia Without Atypia

Endometrial Hyperplasia Without Atypia

To compare the efficacy of Medroxyprogesterone Acetate with dydrogesterone in patients having endometrial hyperplasia (EH) without atypia.

Completed12 enrollment criteria

Study Evaluating Safety and Efficacy of Bazedoxifene/Conjugated Estrogens Combinations in Postmenopausal...

Endometrial HyperplasiaOsteoporosis

The purpose of this study is to determine whether bazedoxifene/conjugated estrogens combinations are effective for the prevention of endometrial hyperplasia and for the prevention of osteoporosis in postmenopausal women.

Completed7 enrollment criteria

Vaginal Micronized Progesterone Versus Levonorgestrel for Treatment of Non-atypical Endometrial...

Endometrial Hyperplasia Without Atypia

The purpose of this study is to compare the efficacy of the vaginal micronized progesterone and Levonorgestrel-releasing Intrauterine System for treatment of non-atypical endometrial hyperplasia in premenopausal women.

Completed5 enrollment criteria

Metformin for the Treatment of Endometrial Hyperplasia

Endometrial HyperplasiaEndometrial Hyperplasia Without Atypia

The purpose of this study is to see if metformin will be effective in making endometrial hyperplasia without atypia better by returning the tissue to a normal state.

Completed15 enrollment criteria

Efficacy of LNG-IUS for Treatment of Non-atypical Endometrial Hyperplasia in Perimenopausal Women...

Endometrial Hyperplasia

The purpose of this study is to compare the efficacy of the Levonorgestrel releasing Intrauterine System (Mirena) and Norethisterone Acetate for treatment of non-atypical endometrial hyperplasia in perimenopausal women.

Completed3 enrollment criteria
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