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Active clinical trials for "Epilepsies, Partial"

Results 71-80 of 222

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

Partial EpilepsyCatamenial Epilepsy

The study will evaluate the effectiveness and safety of an investigational drug-ganaxolone - on partial seizure frequency in adults with epilepsy taking a maximum of 3 antiepileptic medications (AEDs). The study will also evaluate the effectiveness of ganaxolone in females with catamenial epilepsy. Catamenial epilepsy refers to a relationship between seizure frequency and a woman's menstrual cycle, where the number of seizures increases around the time of a woman's menstrual cycle.

Completed41 enrollment criteria

Effect of Repeat Administration of Eslicarbazepine Acetate on the Pharmacokinetics of a Combined...

Partial Epilepsy

The purpose of this study is to investigate whether multiple-dose administration of eslicarbazepine acetate (ESL, BIA 2-093) 800 mg once-daily (QD) affects the pharmacokinetics and tolerability of the components of a combined oral contraceptive (ethinyloestradiol and levonorgestrel).

Completed11 enrollment criteria

Study of PK and Safety of OXC (Oxcarbazepine) XR (Extended Release) as Adjunctive Therapy in Pediatric...

EpilepsiesPartial

Study to evaluate the pharmacokinetics, safety, and tolerability of OXC XR as adjunctive therapy in pediatric subjects with refractory partial epilepsy.

Completed30 enrollment criteria

Efficacy and Safety Study of BIA 2-093 in Combination With Other Anti-Epileptic Drugs to Treat Partial...

Partial Epilepsy

The primary objective of the study is to evaluate the efficacy of eslicarbazepine acetate once-daily at doses of 400 mg, 800 mg and 1200 mg compared with placebo as adjunctive therapy in patients with refractory partial epilepsy over a 12-week maintenance period. Patients who complete Part I may enter a 1-year open-label extension.

Completed19 enrollment criteria

Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy...

EpilepsyPartial

The purpose of this study is to assess whether Lyrica is a safe and effective treatment for partial epilepsy in comparison with an established treatment, Lamictal.

Completed3 enrollment criteria

A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy...

EpilepsyEpilepsies2 more

The purpose of this study is to evaluate the efficacy and safety of topiramate as add-on therapy in epilepsy patients with difficult to treat, partial-onset seizures who are taking one or two standard anti-epileptic drugs.

Completed10 enrollment criteria

Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients...

EpilepsyEpilepsies4 more

The purpose of this study is to assess a possible predictor for weight loss seen in epilepsy patients treated with topiramate.

Completed10 enrollment criteria

Efficacy, Safety, and Tolerability of Oxcarbazepine Monotherapy in Children With Partial Seizures...

EpilepsyPartial Seizures

This study is aimed to collect additional data regarding the efficacy in reducing the frequency of partial seizures, as well as the safety and tolerability, of oxcarbazepine monotherapy in children.

Completed7 enrollment criteria

An Open-Label Extension Study of the Effectiveness and Safety of the Investigational Compound RWJ-333369...

EpilepsyEpilepsies1 more

The purpose of this study is to evaluate the effectiveness and safety of the novel compound RWJ-333369 in reducing the frequency of seizures in patients with epilepsy.

Completed6 enrollment criteria

A Study of Brivaracetam in Subjects With Partial Onset Seizures

EpilepsyFocal

This trial will evaluate the efficacy and safety of brivaracetam (at doses of 50 and 150 mg/day in twice a day administration) as add on therapy in subjects with focal epilepsy

Completed9 enrollment criteria
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