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Active clinical trials for "Seizures"

Results 471-480 of 775

A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients...

EpilepsySeizures

The purpose of this study is to compare the effectiveness and safety of topiramate to standard antiepileptic drugs in children and adults with newly diagnosed epilepsy.

Completed9 enrollment criteria

An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis...

Tuberous Sclerosis ComplexSeizures

This trial consists of 2 parts: a double-blinded phase and an open-label extension phase. The open-label extension phase only will be described in this record. All participants will receive the same dose of GWP42003-P. However, investigators may subsequently decrease or increase the participant's dose until the optimal dose is found.

Completed2 enrollment criteria

Follow-up Study of L059 (Levetiracetam) in Epileptic Patients With Partial Onset Seizures by Open...

EpilepsyPartial

The safety and efficacy of L059 was evaluated in patients who completed "N165 Clinical Trial of L059". They received L059 at a daily dose from 1,000 mg to 3,000 mg in addition to their standard concomitant AEDs

Completed5 enrollment criteria

Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsions

Status EpilepticusConvulsions

The purpose of this study is to evaluate intranasal lorazepam in paediatric status epilepticus. This is a potentially, more effective, safer and cheaper treatment for a common paediatric medical emergency compared to our present first line therapy intramuscular paraldehyde.

Completed5 enrollment criteria

A Study for Treatment of Partial Seizures in Children

Partial Seizures

The purpose of the study is to assess the safety profile of the investigational medication, Depakote Sprinkle Capsules, in the treatment of partial seizures in children ages 3-10.

Completed19 enrollment criteria

Multicenter Trial for Adults With Partial Seizures

Epilepsy

To compare seizure frequency in patients with refactory partial seizures (with or without generalization) who are taking Talampanel versus placebo as an add-on therapy to other licensed concomitant antiepileptic drugs (AEDs) and to determine the safety of Talampanel in this group of patients.

Completed6 enrollment criteria

Study With Subjects 18-65 Years Old With Partial Onset Seizures Who Are Currently Taking Levetiracetam...

EpilepsyPartial

This trial will evaluate the efficacy and safety of UCB44212 as add-on therapy in subjects with focal epilepsy.

Completed12 enrollment criteria

Long-Term, Follow-Up Study Of the Safety And Efficacy Of Levetiracetam In Children With Partial...

EpilepsyPartial

To allow pediatric patients with partial onset seizures an opportunity to receive (as follow-up to studies N01009(NCT00105040)/N01103(NCT00175890) or by direct enrollment) open-label levetiracetam treatment, continue studying cognition and behavior in children, and continue collection of safety/efficacy data.

Completed6 enrollment criteria

Pregabalin Epilepsy Add-On Trial

Partial Seizures

To evaluate the efficacy of pregabalin as adjunctive therapy, using a flexible, optimized dose schedule with dose adjustment based on clinical response and tolerability, compared to placebo in subjects with partial seizures

Completed4 enrollment criteria

To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.

Seizure DisorderPartial

To evaluate the long-term safety and tolerability of pregabalin in patients with partial seizures.

Completed3 enrollment criteria
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