A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients...
EpilepsySeizuresThe purpose of this study is to compare the effectiveness and safety of topiramate to standard antiepileptic drugs in children and adults with newly diagnosed epilepsy.
An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis...
Tuberous Sclerosis ComplexSeizuresThis trial consists of 2 parts: a double-blinded phase and an open-label extension phase. The open-label extension phase only will be described in this record. All participants will receive the same dose of GWP42003-P. However, investigators may subsequently decrease or increase the participant's dose until the optimal dose is found.
Follow-up Study of L059 (Levetiracetam) in Epileptic Patients With Partial Onset Seizures by Open...
EpilepsyPartialThe safety and efficacy of L059 was evaluated in patients who completed "N165 Clinical Trial of L059". They received L059 at a daily dose from 1,000 mg to 3,000 mg in addition to their standard concomitant AEDs
Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsions
Status EpilepticusConvulsionsThe purpose of this study is to evaluate intranasal lorazepam in paediatric status epilepticus. This is a potentially, more effective, safer and cheaper treatment for a common paediatric medical emergency compared to our present first line therapy intramuscular paraldehyde.
A Study for Treatment of Partial Seizures in Children
Partial SeizuresThe purpose of the study is to assess the safety profile of the investigational medication, Depakote Sprinkle Capsules, in the treatment of partial seizures in children ages 3-10.
Multicenter Trial for Adults With Partial Seizures
EpilepsyTo compare seizure frequency in patients with refactory partial seizures (with or without generalization) who are taking Talampanel versus placebo as an add-on therapy to other licensed concomitant antiepileptic drugs (AEDs) and to determine the safety of Talampanel in this group of patients.
Study With Subjects 18-65 Years Old With Partial Onset Seizures Who Are Currently Taking Levetiracetam...
EpilepsyPartialThis trial will evaluate the efficacy and safety of UCB44212 as add-on therapy in subjects with focal epilepsy.
Long-Term, Follow-Up Study Of the Safety And Efficacy Of Levetiracetam In Children With Partial...
EpilepsyPartialTo allow pediatric patients with partial onset seizures an opportunity to receive (as follow-up to studies N01009(NCT00105040)/N01103(NCT00175890) or by direct enrollment) open-label levetiracetam treatment, continue studying cognition and behavior in children, and continue collection of safety/efficacy data.
Pregabalin Epilepsy Add-On Trial
Partial SeizuresTo evaluate the efficacy of pregabalin as adjunctive therapy, using a flexible, optimized dose schedule with dose adjustment based on clinical response and tolerability, compared to placebo in subjects with partial seizures
To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.
Seizure DisorderPartialTo evaluate the long-term safety and tolerability of pregabalin in patients with partial seizures.