Single-photon Emission Computed Tomography (SPECT) to Predict Peritoneal Chemotherapy
Peritoneal CarcinomatosisSPECT was performed in 51 patients after cytoreductive surgery in combination with intraperitoneal chemotherapy. The detected volume was compared to the number of subsequent sequential postoperative intraperitoneal chemotherapy courses that could be performed without further surgical intervention. SPECT data was found to predict feasibility of sequential postoperative intraperitoneal chemotherapy.
Early Screening of Hepatocellular Carcinoma in Cirrhotic Patients: a Prospective Study
CirrhosisHepatocellular CarcinomaAlthough serum alpha-fetoprotein level and abdominal sonography are the main methods to screening hepatocellular carcinoma (HCC) in cirrhotic patients, the adequate time and methods used are not completely well-defined. This study aims to assess the better timing and methods for prospectively screening HCC in patients with cirrhosis
Confocal Reflectance Microscopy of Shave-Biopsy Sites on Skin in Vivo.
Basal Cell CarcinomaMelanoma2 moreThe purpose of this study is to evaluate a new instrument that shines light and takes digital pictures of skin. The goal is to develop a technique that may enable fast and accurate detection of skin disorders and cancers for future clinical diagnosis and surgical use.
Molecular Genetic Basis of Invasive Breast Cancer Risk Associated With Lobular Carcinoma in Situ...
Breast CancerLobular Carcinoma1 moreThis study is being done in order to better understand the biology of an abnormal lesion found in breast tissue called "lobular carcinoma in situ" (LCIS). We are interested in studying LCIS. The LCIS is not a cancer itself, but is a marker for an increased risk of cancer. We would like to look for LCIS in breast tissue removed during surgery from patients with cancer or at high risk for cancer. If LCIS is found, we will search for genes that are expressed (turned on or off) differently than in normal breast tissue. The identification of such genes would help us better understand the biology of LCIS, and its possible relationship to breast cancer.
Patient Selection for Hypoxia Modifying Treatments in Larynx Carcinomas
Larynx CancerThe purpose of this study is to identify in a prospective manner microregional profiles of oxygenation and proliferation based on exogenous and endogenous markers that are predictive for outcome of radiotherapy in squamous cell carcinoma of the larynx and to investigate if these profiles can identify patients that are most likely to benefit from hypoxia modifying treatment strategies like ARCON (Accelerated radiotherapy combined with carbogen breathing and nicotinamide).
Expression Analysis of the COPB 2 and Bcl-2 in Early Stages of Endometrial Carcinoma
Endometrial Carcinoma Cellular DiagnosisCOPB2 is a subunit of the intracellular transport system between cell organelles that participates in the regulation of cell division and differentiation. Bcl-2 is a protein that participates in regulating the process of apoptosis. Through the research,investigators tried to examine and establish the correlation of the expression of these two genes in endometrial cancer at an early stage.
An Expanded Access Treatment Protocol of Enfortumab Vedotin in Subjects With Locally Advanced or...
Locally Advanced or Metastatic Urothelial Carcinoma (UC)The primary purpose of this expanded access program is to evaluate safety and tolerability of enfortumab vedotin (EV) in participants in the United States with locally advanced or metastatic urothelial carcinoma (UC) who have exhausted standard of care therapies and are not eligible to participate in an ongoing EV clinical study. This program will also evaluate the efficacy of EV.
Hypermethylation of VTRNA2-1 Promoter in HCC Outcome
Hepatocellular Carcinoma ResectableThe clinic-pathological data were retrieved from the cancer registry database from the Cancer Center of Chang Gung Memorial Hospital, Linkou branch. Of the 92 HCC patients with partial hepatectomies enrolled. The biological specimen was studied with approval.
Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human...
Cervical Intraepithelial Neoplasia Grade 2/3Neoplasm Cervix4 moreThe European VALHUDES study is a Clinical Performance /Diagnostic Test Accuracy Study that aims to evaluate whether HPV testing with new assays performed on self-samples, collected by means of a vaginal and a urine collection device is as accurate to detect cervical pre-cancer as on cliniciantaken cervical samples.
The Incidence of Pulmonary Embolism During Nephrectomy
Pulmonary EmbolismRenal Cell Carcinoma1 morePatients with renal carcinoma was reported at high incidence of perioperative pulmonary embolism from current study. The investigators aimed to determine the incidence and outcome of this group of patient in the tertiary-care, university hospital and the rate of intraoperative transesophageal echocardiography utility and outcome.