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Active clinical trials for "Equinus Deformity"

Results 41-50 of 56

Clonidine for Tourniquet-related Pain in Children

Polydactyly ToeThumb Hypoplasia30 more

This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of opioid administered under and 24 hours after surgery in children undergoing orthopedic limb surgery with the use of tourniquet. The investigators hypothesize that administration of clonidine to children undergoing limb surgery with the use of inflatable tourniquets would reduce post-procedural pain. This study is a pilot to obtain an effect size. Based on this the investigators will calculate a sample size for the main trial enabling us to reach a power of 0.8 with a significans level of 0.05.

Unknown status12 enrollment criteria

Bracing Compliance and Personality Traits: A Compliance Assessment Program for Scoliosis and Clubfeet...

ClubfeetAdolescent Idiopathic Scoliosis

While studies have shown that better outcomes are associated with brace wear compliance in the scoliosis and clubfoot populations, compliance rates are still poor. Reasons identified by patients, parents and research for not complying with prescribed brace wear include the inconvenience or irritability of the child when in the brace in the case of clubfeet, and fear of looking different from peers, clothes not fitting properly, or discomfort in the case of scoliosis. While reasons for noncompliance are many and can be complex, there has been some research to indicate that personality traits may play a role in brace wear compliance. The primary purpose of the proposed study is to determine if personality traits are related to compliance patterns for individuals undergoing brace treatment for AIS or Clubfeet.

Completed14 enrollment criteria

Exploring the Causes of Clubfoot Using Magnetic Resonance Imaging, MRI

Clubfoot

The purpose of this study is to: compare structural variations observed in the calf and foot of the clubfoot mouse model(pma)with human clubfoot patients antenatally and postnatally; identify features that might be used in future large scale studies to delineate a subtype of human clubfoot associated with lack of response to standard 'Ponseti' manipulation treatments.

Completed3 enrollment criteria

Development of Child With Equinus Deformity Idiopathic

Equinus Deformity

Identification and characterization of the link between psychomotor development and the appearance of associated signs in children with "Equinus Deformity " considered isolated at birth.

Completed5 enrollment criteria

Gait Analysis in Children With Clubfoot Treated With Tibialis Anterior Tendon Transfer

Clubfoot

Patients with clubfoot treated with the Ponseti method and undergoing Tibialis Anterior tendon transfer from a prospective database are evaluated using gait analysis including the Oxford foot model and compared to a group of healthy children.

Completed6 enrollment criteria

Clubfoot DNA Repository

Clubfoot

To build a DNA repository to enable participation in ongoing and future Clubfoot genetic linkage studies.

Completed3 enrollment criteria

Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot)

Clubfoot

The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus (clubfoot). The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be identified in defined populations. Towards this goal, in preliminary studies, Dr. Hecht's group has identified two genes, NAT2 and CASP10, which demonstrate evidence for linkage and association to ITEV.

Completed1 enrollment criteria

Pedobarographic Assessments of Clubfoot Treated Patients

Clubfoot

The purpose of this study is to determine the utility of pedobarographs in evaluating clubfoot post-treatment.

Completed0 enrollment criteria

Gait Analysis in Ponseti Clubfoot

Clubfoot

Patients with clubfoot treated with the Ponseti method from a prospective database are evaluated using gait analysis including a foot model and a disease specific instrument score and compared to a group of healthy children.

Completed6 enrollment criteria

Outcomes of Compliance With Brace Wear in Clubfoot

Clubfoot

It has been shown that compliance with brace wear can significantly improve the treatment outcome of idiopathic clubfoot deformities. Noncompliance rates have been estimated to be around 30-41% with initial orthosis wear after successful treatment with serial castings. These studies have depended on family logs and not objective data. With the development of a monitoring device, this study hopes to examine: (1) actual patient compliance, (2) comparisons of actual wear time and assumed wear time and (3) the relationship of patient wear with clinical outcomes. Hypothesis: Actual patient compliance in foot abduction orthoses (FAO) wear is less than self-reported compliance and noncompliance is correlated to future surgeries.

Completed5 enrollment criteria
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