To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After...
Gastroesophageal Reflux DiseaseGERD1 moreAdministration of esomeprazole 20 mg to subjects who still had heartburn after receiving rabeprazole 10 mg once daily for at least 4 weeks will result in statistically significant improvement of heartburn after 8-week treatment.
Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole...
Erosive EsophagitisTo investigate the impact of initial treatment duration (4-week versus 8-week)of Esomeprazole (40mg) on the rate of symptom relapse and sustained healing of esophagitis in patients with symptomatic erosive esophagitis
Morphological Markers of Gastroesophageal Reflux Disease (GERD)
Eosinophilic EsophagitisGastroesophageal Reflux DiseaseThe purpose of this project is to learn more about a new and promising way to diagnose acid reflux disease using a very high-powered microscope. This special microscope provides much finer detail than typical microscopes previously used for diagnosing reflux, and may help doctors to better identify children with acid reflux.
Study Comparing a Pantoprazole Formulation to the Currently Marketed Tablet for GERD and Erosive...
Gastroesophageal RefluxEsophagitisThe purpose of this study is to demonstrate pharmacodynamic comparability between the pantoprazole spheroid formulation and the marketed tablet formulation.
Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome
Esophageal AdenocarcinomaBarrett's Esophagus1 moreThis is a randomized, open-label pilot study to assess whether treatment with chlorhexidine mouthwash can alter the esophageal and gastric cardia microbiome
Budesonide Orodispersible Tablet vs. Placebo in Active Eosinophilic Esophagitis
Eosinophilic EsophagitisThe purpose of this study is to prove the superiority of a 6-weeks treatment with budesonide effervescent tablets versus placebo for the induction of clinico-pathological remission in patients with acute eosinophilic esophagitis.
OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled,...
Eosinophilic Esophagitis (EoE)This is a clinical trial to test an experimental drug for the treatment of Eosinophilic Esophagitis (EoE)
Study to Confirm the Safety and Efficacy of Tegoprazan in Patients With Healed Erosive Esophagitis...
Healed Erosive EsophagitisThis study is designed to confirm the non-inferiority of Tegoprazan 25mg, compared to Lansoprazole 15mg as maintenance therapy in patients with healed erosive esophagitis confirmed by endoscopy following oral administration once daily(QD) for 6 months.
A Study to Compare the Pharmacokinetic Characteristics of CJ-12420
Erosive EsophagitisTo compare the pharmacokinetics after administration of different formulation of CJ-12420
Maintenance of Remission With Budesonide Orodispersible Tablets vs. Placebo in Eosinophilic Esophagitis...
Eosinophilic EsophagitisThe purpose of this study is to prove the superiority of a 48-weeks treatment with budesonide orodispersible tablets versus placebo for the maintenance of clinico-pathological remission in patients with eosinophilic esophagitis.