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Active clinical trials for "Dry Eye Syndromes"

Results 121-130 of 976

Objective Measurement With TCM Pattern for AIDDES

Sjögren's SyndromeSystemic Lupus Erythematosus1 more

To explore the association with TCM pattern and TCM tongue diagnosis for Autoimmune disease and Dry eye syndrome.

Recruiting12 enrollment criteria

Traditional Chinese Medicine Ultrasonic Atomization Treatment for Dry Eye Disease: A Randomized...

Dry Eye Syndromes

Dry eye disease (DED) is the most prevalent ocular surface disease worldwide. Standard treatments like artificial tears show limited effect. Regarding the ultrasonic atomization, the ultrasonic nebulizer produces consistent steam from the solution with a treatment effect delivered to the ocular surface. We aim to evaluate the effectiveness and safety of traditional Chinese medicine (TCM) ultrasonic atomization as an adjuvant treatment for DED. This is a randomized double-masked, active- and placebo-controlled trial. 200 subjects will be equally assigned to the herbal compound decoction(CD) group, dendrobium caulis (DC) group, houttuynia cordata (HC) group, placebo atomization(PA) group, and artificial tear (AT) group by stratified permuted block randomization. Subjects of CD, DC, HC, and PA groups will receive TCM ultrasonic atomization treatment (6 times/week). All patients will receive hypromellose 0.3% w/v lubricant eye drops for a 1-week wash-out and a 4-month follow-up period. Outcomes included non-invasive tear break-up times, corneal and conjunctival fluorescein staining, and other dry eye-related parameter examined by LipiView II Ocular Surface Interferometer, OCULUS® Keratograph 5M, and slit lamp biomicroscope evaluated by masked clinical assessors at baseline, week 1, 2, 3, 4 and month 2, 3, 4. The other subjective questionnaires like the Ocular Surface Disease Index (OSDI) questionnaire are also selected.

Not yet recruiting17 enrollment criteria

Changes of Clinical Characteristics and Tear Film Biomarkers Following FS-LASIK

Dry Eye

to analyze the clinical and tear molecular profile up to 6 months after FS-LASIK surgery

Recruiting7 enrollment criteria

Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects...

Eyelid DiseasesEyelid Movement Disorders3 more

To demonstrate that DMSt + RF improves eye blink quality in subjects with dry eye disease

Not yet recruiting21 enrollment criteria

Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals

Dry Eye SyndromesAge-Related Macular Degeneration1 more

The purpose of this study is to determine increases in the Omega Index test indicating optimal Omega-3s particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) levels for overall systemic benefits including healthy cardiovascular health and cholesterol levels as shown in the OmegaIndex (OmegaQuant) research.

Active7 enrollment criteria

Epidemiological Study of Dry Eye Disease in Stavanger: Dry Eye Disease in Patients Treated With...

Dry Eye

To investigate prevalence of dry eye disease in Norwegian patients with age-related macular degeneration receiving intravitreal injections, as well as to reveal possible risk factors of DED in this population.

Enrolling by invitation3 enrollment criteria

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101...

Dry Eye Disease

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, versus Vehicle Control in the treatment of Dry Eye Disease in Patients with Autoimmune Disease

Suspended13 enrollment criteria

Study of Platelet Rich Plasma Drops to Moderate Clinically Significant Dry Eye

Dry Eye Syndromes

This is a single center double-masked study with up to four visits. Subjects who have been diagnosed with dry-eye syndrome at Flaum Eye Institute will be enrolled. The purpose of the study is to determine if using platelet rich plasma drops can improve clinically significant dry eye in patients and determine if there is a difference with using two different uses of the plasma tear drops: platelet rich plasma tears and plasma tears without platelets.

Suspended10 enrollment criteria

Three-dimensional Analysis of EMMPRIN on Conjunctival Epithelial Cells Surface in Severe Dry Eye...

Conjunctival DiseasesDry Eye Syndromes

Modifications of cell surface markers (including EMMPRIN) were observed in conjunctival epithelial cells during dry eye syndrome ; this study aims to describe the modifications of the repartition of these cell surface markers before and after initiation of a treatment.

Recruiting16 enrollment criteria

Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface

Dry Eye SyndromeInfectious Keratoconjunctivitis2 more

This study aims to obtain the lacrimal fingerprint for frequent pathologies of the ocular surface and establish a normative base for each of them.

Recruiting4 enrollment criteria
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