
Lanreotide (Somatuline Autogel) in Thyroid-associated Ophthalmopathy Treatment
Thyroid-Associated OphthalmopathyThe main purpose of this study is to evaluate the efficacy and safety of 3 doses of Somatuline Autogel 60mg to control the muscle infiltration and edema, eyelid retraction and extraocular muscular contraction in patients with active thyroid-associated ophthalmopathy of moderate intensity.

ASCEND GO-2: Study of RVT-1401 for the Treatment of Participants With Active, Moderate to Severe...
Graves' Ophthalmopathy (GO)The purpose of the current study is to assess the efficacy and safety/tolerability of three dose regimens of RVT-1401 in the treatment of active, moderate to severe GO participants. In addition, the study is designed to characterize the effect of RVT-1401 exposure on reduction in anti-TSHR IgG

Management of Signs and Symptoms Associated With Dry Eye Disease
Dry Eye SyndromesA prospective randomized, and controlled study to compare the effectiveness of PROKERA® SLIM plus standard of care (SOC) in the PROKERA® SLIM Arm to SOC alone in the Control Arm. Subjects presenting with moderate DED defined as corneal fluorescein staining score of ≥ 3 points out of 9 will be recruited.

Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease
Dry EyeThe purpose of this clinical trial is to investigate the efficacy of a single iLux® treatment in symptomatic CL wearers who have DED (according to the TFOS DEWS II diagnostic criteria), of the evaporative dry eye disease subtype (EDE).

Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms...
Dry Eye SyndromesIn this study, the TearCare System will be compared with standard-of-care warm compress treatment and lid massage in patients with dry eye disease. The objective is to demonstrate that the TearCare System is safe and effective in relieving the signs and symptoms of dry eye disease and that it is superior to a commonly prescribed, standard treatment of warm compress and lid massage. NOTE: All sites have been selected for this study.

Glucocorticoids and Bone in Graves' Ophthalmopathy
Graves OphthalmopathyContinuous use of systemic glucocorticoids decreases bone mineral density and increases fracture risk. Graves' orbitopathy is treated with weekly infusion of high-dose intravenous glucocorticoid. The investigators aim at investigating whether this treatment regimen also affects bone metabolism.

Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease
Dry Eye DiseaseThe purpose of this study is to evaluate the effect of treatment with 0.017% P-321 on Dry Eye Symptoms.

AS-OCT of the Cornea in Thyroid Diseases
Thyroid Eye Diseaseuse the anterior segment optical coherence tomography (AS-OCT) to evaluate the tear meniscus parameters, total corneal thickness (CT), and epithelial thickness in active and inactive thyroid eye diseases (TED) patients and compare them with age-matched controls.

Autologous Blood for Full-thickness Macular Hole
OphthalmopathyAutologous blood for primary and recurrent holes

Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease
Dry Eye SyndromesTo evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in patients with dry eye who are beginning treatment with Xiidra (lifitegrast ophthalmic solution) to reduce the signs and symptoms of dry eye disease.