Lenvatinib and Capecitabine in Patients With Advanced Malignancies
Advanced CancerMalignant Neoplasm of Breast12 moreThere are 2 phases in this study: Phase 1 (dose escalation) and Phase 2 (dose expansion). The goal of Phase 1 of this clinical research study is to find the highest tolerable dose of lenvatinib and Xeloda (capecitabine) that can be given to patients with advanced cancer. The goal of Phase 2 of this study is to learn if the dose of lenvatinib and capecitabine found in Phase 1 can help to control advanced cancer. The safety of this drug combination will be studied in both phases of the study.
Intra-arterial Chemotherapy for Advanced Intraocular Retinoblastoma
RetinoblastomaEye CancerPhase II study of selective intra-arterial infusion of chemotherapy for intraocular retinoblastoma
Pain Relief - Tramadol Versus Ibuprofen
Choroidal MelanomaMelanoma1 moreThe purpose of this study is to assess post operative pain following the insertion of radioactive plaque for choroidal melanoma in patients after receiving either ibuprofen or tramadol.
BCC Excision Revisited
Basal Cell CarcinomaEye Diseases1 moreTo readdress basal cell carcinoma (BCC) in the periocular region to prove histologically controlled surgical treatment efficacy and to identify high-risk characteristics.
B-Receptor Signaling in Cardiomyopathy
CarcinomasAmyloidosis37 moreWe hope to determine the importance of different genes (including B receptors) in anthracycline-induced cardiomyopathy. This has important benefits to patients exposed to anthracyclines, as this could help determine whether certain individuals have increased susceptibility to cardiac injury.
Quality of Life of Eye Amputated Patients in Denmark
Eye CancerPainful Blind Eye2 moreThe purpose of this study is to evaluate eye amputated patients health related quality of life, perceived stress, self-rated health, labour marked participation and socio-economic position. The investigators hypothesis is that quality of life, perceived stress and self- rated health of many eye amputated patients are drastically changed. Eye amputation has a marked negative influence on labour marked participation and socio-economic position of the patients.
Superb Microvascular Intraocular Tumor Imaging Study (SMITIS)
Ocular TumorThe diagnosis and monitoring of intraocular tumors are based on multimodal imaging in addition to the clinical examination (ultra-widefield retinal imaging, echography, angiography). Nevertheless, it may be difficult in cases of retinal hemorrhage, small tumor size or atypical presentation. The study of microvascular flow (Superb Microvascular Imaging, SMI) of intraocular tumors could improve the confidence of differential diagnosis when evaluating these suspicious lesions, or even determine whether a lesion is benign or malignant by describing the vascularization of the lesion. The investigators propose to study the microvascular flow patterns of intraocular tumors prior to proton therapy.
Social-Psychological Aspects of Orbital Exenteration
Eye CancerThe goal of this research study is to learn about the social and emotional factors that may affect the quality of life of patients with cancer of the eye or eye area who have had their facial appearance changed due to an orbital exenteration.
Research of Pathological Imaging Diagnosis of Ocular Tumors Based on New Artificial Intelligence...
Melanoma (Skin)Melanoma in Situ5 moreThe purpose of this study is to establish a standardized process for obtaining digital pathological image information of ocular tumors; use modern pathological techniques to obtain the co-expression information of multiple biomarkers in the pathological tissues of ocular tumors, and finally construct standardized digital ocular tumors with biomarkers Pathology image database.