search

Active clinical trials for "Fetal Membranes, Premature Rupture"

Results 81-90 of 122

Foley vs Propess for Induction of Labor in Women With Term PROM : Mode of Delivery, Maternal and...

Premature Rupture of Membranes at TermMode of Delivery

Premature rupture of membranes at term is a rupture that occurs at term (>37SA) before the start of labor. It complicates 5 to 10% of pregnancies and 6 to 22% of term pregnancies. Althought some studies support efficacy of the Foley catheter for cervical ripening at term in induction of labor with intact membranes, it has not been well studied in women with premature rupture of membranes at term. The aim of this retrospective study at the Montpellier University Hospital is to evaluate the effect of the Foley catheter compared to Propess in women with premature rupture of membranes at term, on the induction of labor and the maternal and fetal complications.

Completed15 enrollment criteria

Domiciliary Versus Hospital Management of PPROM

Preterm Premature Rupture of Membrane

This study is designed to compare efficacy & safety of planned domiciliary versus hospital care for women with preterm prelabor rupture of the membranes (PPROM) on fetal, neonatal and maternal outcome.

Completed7 enrollment criteria

Outpatient Management of Preterm Prelabor Rupture of Membranes

Management of Preterm Prelabor Rupture of Membranes

Home-care management is possible if patients are clinically stable forty-eight hours after Preterm Prelabour Rupture of the membrane with no clinical or biological signs suggestive of intrauterine infection. Several retrospective studies have highlighted the safety of such outpatient management for women with nonthreatening Preterm Prelabour Rupture of the membrane. This prospective cohort study will compare inpatient versus outpatient management of preterm Prelabour rupture of membrane regarding latency, intra-amniotic infection, birth weight, and neonatal complications at 28 to 34 weeks of gestation after 48 hours of admission to Ain-Shams University Maternity Hospital.

Completed7 enrollment criteria

Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes...

Premature Rupture of Membrane

The objective of the study is to compare a new antibiotic protocol with the current prophylactic treatment in routine use and to evaluate obstetric and neonatal outcome: preterm labor, chorioamnionitis and early onset sepsis

Unknown status7 enrollment criteria

Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications,...

Vaginal InfectionsBacterial Vaginosis3 more

The purpose of this study is to determine whether screening of pregnant women with history of previous preterm delivery, once a week, for bacterial vaginosis using VA-SENSE, and treatment of positive women will reduce the risk of spontaneous preterm birth. We will compare between the effectiveness of once a week screening and once during pregnancy screening.

Unknown status7 enrollment criteria

Core-temperature Monitoring in Patients With PPROM

Preterm Premature Rupture of Fetal Membranes

The most common reason for preterm prelabor rupture of membrane (PPROM) is an ascendance of infection. Moreover PPROM is one of the main risk factors for chorioamnionitis. PPROM-related morbidity and mortality is higher in the neonate than in the mother, especially in case of intrauterine inflammation. Of note, the most common biomarkers like CRP and leucocytes are not specific for uterine infections and have not been proven useful in these particular cases. Studies in intensive care medicine could show that there is a possible correlation between onset of infection and body-core-temperature. The OvulaRing® is a non-invasive thermometer measuring the intravaginal temperature every 5 minutes. It was originally invented to assess the moment of ovulation and optimize fertility. Twenty patients with verified PPROM between gestation week 22 and 27 should be included in this study. After gynecological and physical examination within verification of PPROM women will be informed and invited to participate in this study. Subsequently informed consent will be obtained and the OvulaRing® placed into the vaginal fornix. The investigators aim to describe a possible correlation between core-temperature and common biomarkers in clinical use for the detection of chorioamnionitis in patients with PPROM to possibly assess the optimal time for delivery subsequently.

Withdrawn7 enrollment criteria

The Cervical Cap in the Diagnosis of Rupture of Membranes in the Second Trimester

Fetal MembranesPremature Rupture1 more

Early preterm premature rupture of membranes (PPROM) complicates 0.7% of pregnancies. When PPROM occurs before the 24th week,the risk of fetal and neonatal death is 70%. There is also a high risk of neonatal and maternal morbidity. When the diagnosis of PPROM is uncertain by physical examination, additional tests are needed. These tests have false positive and false negative rates. The gold standard for diagnosing PPROM is amniocentesis and dye test. This procedure has a risk of infection and abortion.Our hypothesis is that by using a cervical cap for 6 hours and repeated ultrasound exams we can diagnose or rule out PPROM in cases which are uncertain. Our study group will be pregnant women gestational age 14-23, suspected of having PPROM.

Withdrawn6 enrollment criteria

Does Nipple Stimulation Shorten Time to Vaginal Birth in Women With Term PROM?

Premature Rupture of Fetal Membranes

Premature Rupture of Membranes (PROM) is defined as the rupture of membranes before the onset of regular uterine contractions. PROM occurs in approximately 10% of all pregnancies (ranging from 2.7% to 17%), with 60% to 80% of cases occurring at term. Approximately 90% of patients' experience PROM enter spontaneous labor within 24 hours, but disagreement exists among health care providers on the optimal management of women with PROM, particularly the need for and timing of inductions. Nipple stimulation is a non-medical natural method for induction of labor. Previous studies demonstrated its effectiveness for initiating labor within 72 hours in women with favorable cervices. The actual mechanism by which such a technique results in cervical ripening is not well understood. In this study, we aim to assess the effectiveness of nipple stimulation in gravid women with term PROM choosing expectant management.

Unknown status11 enrollment criteria

Identification of Microbial DNA in Maternal Plasma After PPROM

Preterm Rupture of Membranes

This study evaluates the use of metagenomic next generation sequencing in identifying microbial DNA in plasma samples of patients with preterm premature rupture of membranes.

Completed4 enrollment criteria

Fetal and Maternal Outcome in Preterm Premature Rupture of Membranes (PPROM)

Premature Rupture of Membrane

The aim of this study is to compare fetal and maternal outcome in cases of PPROM before 34 weeks versus after 34 weeks.

Completed2 enrollment criteria
1...8910...13

Need Help? Contact our team!


We'll reach out to this number within 24 hrs