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Active clinical trials for "Fistula"

Results 511-520 of 712

Hemopatch as a Tool to Prevent Biliary Fistula in Liver Surgery.

Biliary FistulaSurgery

The aim of the study is to investigate the use of Hemopatch to prevent biliary fistula in patients submitted to surgery for malignancy.

Completed4 enrollment criteria

Laser Closure of Anal Fistula (FiLaC)

Anal FistulaFistula in Ano1 more

Laser closure of the perianal fistula is the minimally invasive and low complication rate procedure which is a life-saving way for complex fistulas, preserving anal sphincter injury. Unfortunately, wide range success rate reported before (30-80%), the investigators are searching to reach better rates. Internal closure of the fistula orifice offered by some authors. The investigators are aimed to identify the efficiency of this.

Unknown status5 enrollment criteria

Anastomotic Techniques in Pancreaticoduodenectomy

Pancreatic CancerPancreatic Fistula

There are two principal ways of draining the remnant of the pancreas back into the intestine after removal of the head of the pancreas for cancer. This can be performed either to the jejunum or to the stomach. The aim of this study is to randomly allocate consenting patients to one of the two arms to study whether the leak rates from the anastomosis and the outcomes after the surgery are affected. Previous papers have shown similar results in both groups although non randomized data suggested that the Pancreaticogastrostomy (drainage into the stomach) may be superior

Unknown status7 enrollment criteria

Autologous Stem Cells Derived From Lipoaspirates for the Non-Surgical Treatment of Complex Perianal...

Anal Fistula

This comparative, multicentre, randomised clinical trial is designed with two parallel groups that will follow a treatment either with an autologous implant of ASCs (Adipose Derived Stem Cells) and fibrin glue (tissue adhesive material) or with fibrin glue alone for the non-surgical treatment of complex perianal fistula.

Unknown status22 enrollment criteria

Treatment of Lower Transsphincteric Perianal Fistula: Fistulotomy With Marsupialization vs Open...

Perianal FistulaTranssphincteric Anal Fistula

This study will compare the results of marsupialization versus open wound after fistulotomy in low transsphincteric perianal fistulas.

Unknown status9 enrollment criteria

Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy

Anal Fistula

Patients with anal fistula who will undergo anal fistulotomy will be randomized into one of two groups; the first group will receive topical phenytoin therapy postoperatively and the second group will not receive such topical treatment.

Unknown status4 enrollment criteria

One-layer Versus Two-layer Duct-to-mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy

Pancreatic Fistula

The aim of this study is to investigate a new pancreaticojejunal (PJ) anastomosis procedure named "One-layer duct-to-mucosa pancreaticojejunostomy" in pancreatoduodenectomy, which could provide a feasible option to pancreatic surgeons for patients with pancreaticoduodenectomy.

Unknown status8 enrollment criteria

Trial of Omental Roll-up Technique on Pancreato-jejunostomy Anastomosis for Reducing Perioperative...

Periampullary CarcinomaPancreatic Fistula

Despite the fact that pancreatoduodenectomy is the standard treatment of malignant tumor at periampullary area, the morbidity and mortality rate with intra-abdominal collection, post pancreatectomy hemorrhage, and delayed gastric emptying, is still high at approximately 50-60%. The causes of these complications usually come from post-operative pancreatic fistula. Nowadays, several methods have been reported to reduce the incidence of pancreatic fistula after undergoing pancreatoduodenectomy, such as pancreatic stenting, the use of intravenous somatostatin, the use of sealant material and wrapping anastomosis by soft tissue. Wrapping pancreato-jejunal anastomosis with omentum is not a complicate procedure and requires no extra treatment expenses of the patient. It has been reported this technique has been applied in the non-randomized controlled trials and their data have significantly shown that the technique could reduce pancreatic fistula rate. Therefore, the researchers want to conduct an RCT study to compare complication rates between omental roll-up pancreato-jejunal anastomosis and non-omental roll-up groups.

Unknown status3 enrollment criteria

Technical Strategies for Pancreatic Fistula Prevention After Pancreaticoduodenectomy in High-risk...

Pancreatic Fistula

This trial will investigate what surgical technique between pancreaticogastrostomy and pancreaticojejunostomy with transanastomotic externalized drains is associated with the lowest rate of pancreatic fistula after pancreaticoduodenectomy in case of high-risk pancreatic remnants.

Completed8 enrollment criteria

Trial Comparing the Incidence of Steal Syndrome in the Two Types of anTEcubitaL Fossa Arteriovenous...

Arteriovenous FistulasRenal Failure2 more

Background: Arteriovenous fistula (AVF) is a form of vascular access for haemodialysis. An AVF is normally created at the level of the wrist, but occasionally it is created in the elbow when there is no suitable vessel in the forearm. The most common type of elbow (antecubital) fistula (AFF) is a brachiocephalic fistula, which carries significantly higher risk of steal syndrome (AVF-associated hand ischaemia) than wrist fistulas. More recently, AFF using proximal radial or ulnar artery as inflow has been described and shown to have a lower rate of Steal syndrome than brachiocephalic fistula. This study aims to investigate the incidence of steal syndrome between AFF using brachial artery and that using the proximal radial/ulnar artery as inflow.

Completed2 enrollment criteria
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