Active clinical trials for "Fractures, Bone"

This trial is conducted in Africa, Europe and Middle East. This trial investigates the efficacy and safety of three dose levels of Norditropin® (growth hormone) as compared to placebo in the treatment of tibia fractures. The trial will be conducted in two parts: in the first part, the patients will be evaluated with regard to efficacy (fracture healing) and safety at short time intervals until week 24 post-surgery. In the second part, long-term safety and fracture healing up to 12 months post-surgery will be evaluated.

Patients with hip fractures have suffered the most devastating consequence of osteoporosis; and yet, they are rarely if ever tested or treated for the condition, even though they remain at high risk of recurrent fracture. We hypothesize that, compared with usual care, an allied health professional-run osteoporosis service (case management) will be able to increase testing and treatment of osteoporosis in patients at high risk of fracture.

The primary objective of this proposed research is to improve the quality of care for patients who present to the Emergency Department with osteoporosis and a fracture of the wrist, by increasing the use of proven efficacious osteoporosis treatment. This is the primary study outcome, and it is defined as starting any one of hormone therapy, a bisphosphonate, raloxifene, or calcitonin within 6 months of a fracture of the wrist. The study hypothesis is that a quality improvement intervention (with multiple components that include a notification system for primary care physicians, patient-specific reminders, locally generated treatment guidelines endorsed by opinion leaders, and patient education and counseling) will lead to increased use of proven efficacious osteoporosis treatments in patients eligible for secondary prevention. This hypothesis will be tested by comparing the intervention with usual care controls, in a prospective nonrandomized controlled trial.

Acute ankle fractures are common in children. Most of these are stable and have a low risk of problems in the future. Even though these fractures are benign, these injuries are often casted for a fixed time period, which is inconvenient, expensive, and does not appear to be a practice that has been proven to be scientifically correct. Therefore, in this study, in healthy children with low-risk ankle fractures, we, the investigators at the Hospital for Sick Children, will examine if a removable ankle brace is at least as good as casting with respect to how well and how fast children return to their usual activities. In addition, we will compare the costs of each method for the patient and the health care system. Successful management of low-risk fractures with an ankle brace will allow for several advantages over the use of the cast. These advantages include the possibility of returning to normal activities faster, fewer visits to specialty hospital clinics, and significant cost savings.

The study will compare the functions outcomes between two different rehabilitation protocol after operated weber b ankle fractures

In surgery under general anesthesia due to nasal bone fracture, laryngeal mask airway or tracheal intubation has been used. However, it has not been investigated that the difference of recovery profiles according to use of laryngeal mask airway or tracheal intubation in nasal bone fracture surgery. The aim of study is to evaluate the efficacy of the laryngeal mask airway regarding recovery profiles and airway complications, compared to tracheal intubation.

The aim of this current prospective study is to evaluate the effectiveness of an open reduction and internal fixation {ORIF} by distal ulna hooked locking compression plate (lcp) in treatment of isolated displaced distal ulna fracture in adult " without concomitant distal radius fractures.

The humerus forms the bone structure of the arm area between the shoulder and the elbow. Proximal humerus is the upper end of this bone that joins with the shoulder. While proximal humerus fractures occur with high-energy trauma such as traffic accident, fall from height, gunshot injury in young patients, these fractures happen with a simple trauma in elderly patients. Surgical intervention is generally not considered in the proximal humerus fractures treatment. Exercises have very important benefits in the post-fracture period. These exercises allow the shoulder and arm to regain their former mobility. In addition, electrotherapy which is one of the auxiliary methods in the treatment process, is the use of the physical effects of the electric current for therapeutic purposes. The aim of interferential current therapy, which is a frequently used electrotherapy method, is to accelerate recovery, fracture healing, and reduce pain. The aim of this study is to investigate the effect of interferential current therapy on shoulder functions, pain and disability in patients with conservatively treated proximal humerus fractures. Patients will be randomly divided into 2 groups according to the preformed form. The reason why patients are randomly divided into 2 groups (randomization) is to make the study more objective. You have a 50% chance to join one of the 2 treatment groups. An orthopedic rehabilitation program consisting of the same exercise program will be applied to regain shoulder and arm functions for all patients participating in the study. In addition to exercise therapy, active interferential current therapy will be applied to the first group for 3 days a week before the exercises, and sham electric current therapy will be applied to the second group. Being in the second group will not affect the treatment process negatively because of interferential current is not an absolute treatment method for patients with fractures. Shoulder functions, pain (visual analogue scale), disability and range of motion will be evaluated at the end of the exercise program (6th week), 10th and 22nd weeks of all patients who accepted to participate in the study. In addition, the amount of acetaminophen usage will be noted at each visit.

A randomized controlled trial to assess the efficacy and safety of the prolonged compartment psoas block for analgesia and anesthesia for femur surgery in the elderly

This trial aims to develop and test the efficacy of a digital media based physical therapy protocol on patients after surgical fixation and non-operative treatment of distal radius fractures.It is hypothesized that there will not be a difference in outcomes for patients after surgical fixation of distal radius fractures with traditional physical therapy and digital media based therapy