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Active clinical trials for "Gallstones"

Results 271-280 of 310

Prospective Evaluation of Residual Bile Duct Stone by Peroral Cholangioscopy After Conventional...

Gall Stones

Gallstone disease affects over 20 million Americans. Among patients with gallbladder disease, the prevalence of choledocholithiasis (stones in the bile duct) is estimated to be 10-20%. Endoscopic retrograde cholangiopancreatography (ERCP) is considered the standard of care for removing stones in the bile duct utilizing a variety of conventional methods including biliary sphincterotomy, sphincteroplasty, extraction balloon, retrieval basket, and mechanical lithotripsy. After removal of stones from the bile duct, an occlusion cholangiogram is usually performed to confirm complete bile duct clearance. However, cholangiogram can miss residual stones in 11- 30% of cases - especially in the setting of a dilated bile duct, large stones, severe pneumobilia, juxtapapillary diverticulum, primary sclerosing cholangitis, and after lithotripsy (mechanical, electrohydraulic, or laser). The approach to patients with choledocholithiasis requires careful attention because missed bile duct stones can cause recurrent biliary symptoms, pancreatitis, cholangitis, and has significant cost implication with the need for repeat imaging and/or procedures.

Completed12 enrollment criteria

The Discovery of the Double Sphincter in Gallbladder

Gallstone

We found a new Double sphincter which located in the neck of gallbladder,we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.

Unknown status2 enrollment criteria

ESTES Snapshot Audit 2018

Cholangitis; GallstonePancreatitis Gallstone1 more

To explore differences in patients, techniques and outcomes across the international cohort to identify areas of practice variability in the presentation and management of acute complicated calculous biliary disease.

Completed16 enrollment criteria

The Risk Factors of Symptomatic Gallbladder Stone: Age-Sex Matched Case-control Study Performed...

Gallstone

The main purpose of this study is to investigate the region-specific cause of gallbladder stone incidence in Jeju Self-Governing Province, Korea.

Completed8 enrollment criteria

Is Routine Use of Histopathological Examination Necessary After Cholecystectomy ?

Cholelithiasis

Cholecystectomy has been made with benign conditions usually. The aim of this study is to compare the macroscopic evaluations of the cholecystectomy specimens with it's histopathological examinations.

Completed8 enrollment criteria

Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis...

Choledocholithiasis With Cholecystitis With ObstructionCholedocholithiasis With Acute and Chronic Cholecystitis1 more

The ideal management of cholecysto-choledocholithiasis is an open cholecystectomy (OC) with the common bile duct (CBD) exploration worldwide. The single setting 2-stage approach- endoscopic retrograde cholangiopancreatography (ERCP), endoscopic sphincterotomy (EST), and CBD clearance followed by laparoscopic cholecystectomy (LC) offers an advantage, mainly by reducing the hospital stay, the cost, and the morbidity. Investigators did a prospective study in patients admitted for the management of the cholecysto-choledocholithiasis in the Department of Surgery at the Lumbini Medical College and Teaching Hospital from November 2012- October 2015. They underwent 2-stage ERCP+LC in a single setting and investigators compared them with 2-stage OC+CBD exploration in a single setting approach. The patients with the open procedure were the investigator's control groups. All the included cases in the study were elective.

Completed6 enrollment criteria

Laparoscopic Cholecystectomy Using Airseal in Children

Gall Stones (& [Calculus - Gall Bladder])Cholecystitis6 more

The goal of this observational study is to compare the use of Airseal versus a standard insufflation, in children who underwent laparoscopic cholecystectomy, between January 2021 and December 2022. The main questions it aims to answer are: amount of analgesics consumed postoperatively mean digital pain scale Data are directly extracted from patients medical files. The investigators will compare the Airseal group (A group) to the Standard insufflation group (S group) to see if the A group consumes significatively less analgesics and are less painful than the S group.

Completed4 enrollment criteria

Success of Intraoperative Cholangiography

CholecystolithiasisCholedocholithiasis

The purpose of the present study was to evaluate the success of routine use of intraoperative cholangiography (IOC ) and to examine the factors that are hindering the performance of intraoperative c-arm cholangiography.

Completed2 enrollment criteria

Complications After Endoscopic Retrograde Cholangiopancreatography

Choledocholithiasis With Acute Cholangitis (Diagnosis)Acute Pancreatitis Due to Gallstones

Retrospective study to analyze benign complications and malignancy risks after ERCP with sphincterotomy. All patients who received a ERCP with sphincterotomy for a benign disease will be included. Post-ERCP hepato-biliary complications in the follow-up will be registered.

Completed3 enrollment criteria

Potential Pulmonary Benefit of Low Pressure Laparoscopic Cholecystectomy in Selected Patients

Cholecystitis/CholelithiasisCholecystitis; Gallstone1 more

Standard Pressure Laparoscopic Cholecystectomy,as the standard for cholecystectomy, can lead to about 15% of pulmonary atelectasis. According to literature, low pressure laparoscopic cholecystectomy is thought to probably decrease cardio-pulmonary related complications and postoperative pain. However, the previous studies have presented controversial results. Our study aim to evaluate the potential pulmonary benefit of low pressure laparoscopic cholecystectomy in elderly or patients accompanied with cardio-pulmonary disorders.

Unknown status8 enrollment criteria
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