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Active clinical trials for "Gastroesophageal Reflux"

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Incidence of Reflux Esophagitis After Pancreaticoduodenectomy

Reflux Esophagitis

Reflux esophagitis is a common complication following distal gastrectomy. According to the investigators preliminary data, an Roux-en--Y gastrointestinal reconstruction in pancreaticoduodenectomy is associated with higher rates of reflux esophagitis. In this study, the investigators will investigate the incidence of reflux esophagitis after above procedure by the 24-h pH monitoring of esophagogastric junction.

Unknown status7 enrollment criteria

Outcomes for Patients With Gastro-Esophageal Reflux Disease

Gastro-esophageal Reflux Disease

Gastro-esophageal reflux disease (GERD), the most common cause of erosive esophagitis (EE), remains highly prevalent worldwide. GERD poses substantial burden on both patients and society. EE treatment patterns and unmet needs have been well-studied overseas, but evidence gaps still exist in China. To fill these evidence gaps, real-world evidence for GERD and EE are needed. To understand GERD market we will analysis :Patient profile,GERD patient journey within hospital (first present, get diagnosed, receive initial and maintenance treatment),medication cost,department differentiation. To investigate current treatment patterns of GERD / EE in China we will analysis: Current agents used and treatment duration in clinical practice treatment patterns by different reimbursement status treatment pattern by EE/NERD. To get healing rate of EE we will analysis: Real-world efficacy of the current standard treatment (i.e. PPIs) for patient with two test results of gastroscopy. The data required for this project are accessible in hospital electronic system; no specific data collection tools or methods are required for this project design. Only algorithms for retrieving and extracting eligible patients' records are required and will be developed by HLT based on the eligibility criteria defined in this protocol.

Unknown status17 enrollment criteria

Risks of Gastroesophageal Reflux in the Endotracheal Intubation or the I-gel

Gastroesophageal Reflux in Laparoscopy

In the use of the second supraglottic airway device- i-gel in the laparoscopic pneumoperitoneum and Trendelenburg (LPT) surgical positioning, our data reported that the leak fraction in the i-gel group was higher than in the endotracheal tube group.1 These air leak may be gone into the GI tract and cause the gastric distension resulting in the increasing risk of aspiration. Few studies investigated whether the risk of occurrence of the gastroesophageal reflux (GER), the changes of the lower esophageal sphincter (LES) while the GER occurred, and the stomach fullness in the i-gel group than in the endotracheal tube group. We aim to observe the changes of gastroesophageal function parameters by esophageal manometry, pH impedance, and intra-abdominal pressure before and after laparoscopic pneumoperitoneum during anesthesia, all via the second SADs.

Unknown status6 enrollment criteria

Narrow-band Imaging, Autofluorescence Imaging and Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease

Aim of this study is to compare the efficacy of narrow band imaging (NBI) and autofluorescence imaging (AFI) to distinguish subtle mucosal change related to acid reflux that is not visible in standard white light imaging (WLI) endoscopy, and help indicating the diagnosis of gastroesophageal reflux disease (GERD).

Unknown status9 enrollment criteria

Comparison of Treatment Outcome and Cost-effectiveness for GERD

Gastroesophageal Reflux

This study was designed to evaluate the effectiveness of laparoscopic antireflux surgery for treatment of gastroesophageal reflux disease (GERD) comparing with that of non-surgical treatment.

Unknown status6 enrollment criteria

Radiofrequency Ablation in Patients With Barrett's Esophagus

Barrett's EsophagusRadiofrequency Ablation1 more

The aim of this study is to establish a nationwide registry to collect data regarding the treatment of Barrett's Esophagus (BE) with radiofrequency ablation. The objective of this registry is to increase the number of data and therefore obtain a raise of quality assurance and improve outcome and patient security. Furthermore to provide participating physicians information and experience for treatment details in the therapy of BE.

Unknown status2 enrollment criteria

Systematic IPP VS Symptomatic IPP in GERD Prevention After POEM for Achalasia. . A Comparative Retrospective...

AchalasiaGastroesophageal Reflux

POEM is a minimally invasive endoscopic therapy that is highly efficacy in the treatment of achalasia of any type. POEM has an increased risk of GERD. Systematic PPI therapy has never been studied for the prevention of post-POEM GERD. The investigators wish to retrospectively compare patients who have received routine PPI therapy vs. patients who don't.

Unknown status10 enrollment criteria

Gastric Reflux and Sinonasal Symptoms

Gastric RefluxGastro Esophageal Reflux

The study is conducted to: study correlation between sinonasal troubles & GERD Assess whether antireflux therapy improve state of sinus in patients complaining from reflux & sinonasal symptoms

Unknown status5 enrollment criteria

Barrett's Esophagus Patient Registry

Barrett EsophagusEsophageal Adenocarcinoma1 more

The ultimate goal of the Barrett's Esophagus Patient Registry is to help develop more effective targeted screening strategies and treatment options for Barrett's esophagus and esophageal adenocarcinoma (EAC). We plan to do by developing a registry that will serve as a platform. Examples of analyses could include identifying genetic determinants and biomarkers that predict BE, progression of BE to EAC, as well as the response to therapies.

Unknown status7 enrollment criteria

24 Hour Esophageal and Electrogastrography to Investigate the Mechanism of Reflux Esophagitis

Reflux Esophagitis

We hypothesize that gastric dysrhythmias may predispose the occurrence of gastroesophageal reflux.

Unknown status6 enrollment criteria
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