Crossover Bioequivalence Study of Oxcarbazepine 600 mg Suspension Under Fasted Conditions
SeizuresThe objective of this study was to prove the bioequivalence of Roxane Laboratories' Oxcarbazepine Suspension 600 mg under fasted conditions.
Bioequivalency Study of Levetiracetam 1g Under Fasted Conditions
SeizuresThe objective of this study was to prove the bioequivalence of Levetiracetam 1000 mg Tablets under fasted conditions
Bioequivalency Study of Levetiracetam 750 mg Tablets Under Fed Conditions
SeizuresThe objective of this study was to prove the bioequivalence of Levetiracetam 750 mg Tablets under fed conditions
Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not...
Epilepsy With Simple or Complex Partial Onset SeizuresThis is an 18-week, double-blind, multicenter study with gradual conversion from previous antiepileptic therapy to eslicarbazepine acetate monotherapy in subjects with partial epilepsy.
Efficacy and Tolerability of Levetiracetam Add-On Treatment in Refractory Pediatric Patients With...
EpilepsyDouble-blind, randomized, placebo-controlled, multi-center clinical trial conducted to evaluate levetiracetam as adjunctive therapy in children (4-16 years) with refractory partial onset seizures.
Bioequivalency Study of Oxcarbazepine 600 mg Tablets Under Fed Conditions
EpilepsySeizuresThe objective of this study was to assess the bioequivalence of a potential generic 600 mg oxcarbazepine tablet formulation with Novartis Pharmaceutical's 600 mg oxcarbazepine tablet, Trileptal, folloiwng a single 600 mg dose administered with food.
The Effect on Cognition of Terminating ECT Induced Seizures With Propofol
Major DepressionParticipating subjects are those who are referred for electroconvulsive therapy (ECT) for severe depression who have agreed to the protocol. The control group receives ECT as usual. The other group receives propofol to terminate the ECT-induced seizure timed so that the seizure lasts at least 25 seconds. Extensive neuropsychological testing is being done on both groups before beginning ECT and within 48 hours after the 6th treatment. Multiple markers of the rapidity of recovery from anesthesia are being obtained from all subjects for 6 ECTs.
TOBY (TOtal Body hYpothermia): a Study of Treatment for Perinatal Asphyxia
Asphyxia NeonatorumHypoxia2 moreHypothesis: Prolonged whole body cooling in term infants with perinatal asphyxial encephalopathy reduces death and severe neurodevelopmental disability. This study aims to determine whether whole body cooling to 33-34°C is a safe treatment that improves survival, without severe neurological or neurodevelopmental impairments at 18 months, of term infants suffering perinatal asphyxial encephalopathy.
A Comparison of a Currently Marketed Hearing Aid Programmed With Two Different Fitting Methods
Hearing LossThis study is designed to investigate the benefits of the hearing aid in the laboratory and in daily life when fitted with two different methods. Subjective and objective evaluations will be made. The aim is to show the benefits of the hearing aids with both fitting methods with the help of data obtained, and to improve the available fitting methods in order to further increase the benefit for people with hearing disorders in situations where the standard method and those trained to perform it are not available.
Turmeric as Treatment in Epilepsy
EpilepsyDravet Syndrome3 moreThis is a single center open-label pilot clinical trial of patients 1-70 years of age with greater than 6 seizures per month diagnosed with Dravet Syndrome, Lennox-Gastaut Syndrome, Tuberous Sclerosis, or focal seizures. Twenty patients will be enrolled and treated with a stable dose of orally administered turmeric oil daily for 3 months. Patients and caregivers will be asked to keep a seizure diary logging all clinical events during the course of the study. Serum comprehensive metabolic panel, complete blood count with differential, and antiseizure medication levels, will be monitored at baseline, 1.5 months, and at the end of 3 months.