
Liquid Protein Preloads With Different Carbohydrate Types Effects on the Glycaemic and Insulinaemic...
DiabetesImpaired Glucose Tolerance1 moreThis study hypothesizes that milk protein consumed together or shortly before a white rice or white bread carbohydrate meal exerts different influence on the glycaemic, insulinaemic responses.

ACute and Chronic Effects of Saxagliptin
Impaired Glucose ToleranceGlucose ACCES study will explore the acute and long term (12-week treatment) effects of saxagliptin in patients with impaired glucose tolerance during fasting and after a standardised breakfast. The investigations will be performed on: glycemic parameters on cardiovascular parameters

Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance
Impaired Glucose ToleranceResveratrol is a substance found in many plants, including grapes and red wine, which is widely used as a nutritional supplement. Studies in cells and lower animals show that resveratrol has many potential benefits, including prolonging lifespan, preventing cancer and heart disease and normalization of glucose metabolism. Although use of this agent shows great promise in the treatment and/or prevention of diabetes, there have been no studies reported to date in humans. As an initial step, this proposal is for a 6 week pilot study of resveratrol treatment in older adults with impaired glucose tolerance (IGT) in order to explore its effects on post-meal blood glucose metabolism. Preliminary studies will also be conducted to explore how resveratrol works by studying cellular function (in muscle samples obtained from study participants) and by testing resveratrol's effect on blood vessel function.

Study to Evaluate Safety and Efficacy of PreCrea® on Subjects With Higher Than Normal Blood Sugar...
Diabetes MellitusPre-Diabetes2 moreThe purpose of the study is to evaluate the efficacy and safety of PreCrea® on subjects with higher than normal blood sugar levels.

Postmarketing Clinical Study on AO-128
Impaired Glucose Tolerance (IGT)The purpose of open-label study is to evaluate the efficacy and safety of AO-128 (Voglibose) 0.6 mg/day in patients with impaired glucose tolerance (IGT) who had been non-responsive to diet therapy and exercise therapy, and follow up the progress after the end of treatment in patients who was assessed as normoglycemic.

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired...
Type 2 Diabetes MellitusImpaired Glucose ToleranceThis was a 10-week, placebo-controlled, randomized study to investigate the effect of injectable IL-1B antagonist, Canakinumab , in participants with impaired glucose tolerance or Type 2 Diabetes Mellitus (T2DM) already treated on different background diabetes therapies.

Physical Exercise Versus Rosiglitazone in CAD and Prediabetes
Impaired Glucose ToleranceThe aim of this study is to prospectively assess the relative benefits of either treatment with rosiglitazone or physical exercise on endothelial function in patients with impaired fasting glucose or impaired glucose tolerance and coronary artery disease (CAD).

A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With...
Pre-diabetesThis is an exploratory study to assess whether vildagliptin, an unapproved drug, can increase insulin secretion in subjects with pre-diabetes who have a defect in the insulin response and elevated levels of fasting glucose.

Efficacy and Safety of Nateglinide Treatment in Renal Transplant Recipients
Renal Transplant RecipientsPosttransplant Diabetes Mellitus1 moreThe objective of the present study is to evaluate both the efficacy and safet of nateglinide in renal transplanta recipients with posttransplant diabetes mellitus or impaired glucose tolerance. Primarily will the change in glucose tolerance and acute insuline responce be addressed.

Efficacy and Safety of Vildagliptin in Subjects With Impaired Glucose Tolerance
Prediabetic StateThe purpose of this study is to assess the safety and effectiveness of vildagliptin, an unapproved drug, compared to placebo in lowering post-meal blood glucose levels in people with pre-diabetes who have high blood sugar levels after meals.