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Active clinical trials for "Deafness"

Results 301-310 of 613

Bone Conduction Auditory Performance Via the Tooth for Single-Sided Deafness

Unilateral Hearing Loss

The purpose of this study is to determine the safety and efficacy of using bone conduction via the teeth to treat Single-Sided Deafness (SSD).

Completed29 enrollment criteria

Esteem Totally Implantable Hearing System

Mild to Severe Sensorineural Hearing Loss

To evaluate the safety and efficacy of the Esteem Totally Implantable Hearing System in subjects suffering from mild to severe hearing loss.

Completed31 enrollment criteria

A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease

Sensorineural Hearing LossAutoimmune Inner Ear Disease

The purpose of this study is to determine if Anakinra (an interleukin-1 receptor antagonist) can improve hearing thresholds in those patients with Autoimmune Inner Ear Disease (AIED) that did not respond to oral steroid therapy for a sudden decline in hearing. The patients to be enrolled will have recently completed a course of oral steroids and demonstrated no change in their audiometric thresholds following corticosteroid therapy.

Completed19 enrollment criteria

Balance in Children With Cochlear Implants

SevereProfound Deafness

The purpose is to test the balance of children with unilateral,bilateral cochlear implants and patients having unilateral implants before,bilateral implants after surgery,using the Bruininks-Oseretsky Test 2nd ed. to find out if the cochlear implants have an effect.

Completed3 enrollment criteria

Study of Low Level Laser Therapy and Word Recognition in Hearing Impaired Individuals

Sensorineural Hearing Loss

The purpose of this clinical study is to determine the effectiveness of low level laser light therapy when applied around the head and ears in improving unaided word recognition in ears with sensorineural hearing loss.

Completed26 enrollment criteria

Chronic Electrical Stimulation of the Auditory Cortex for Intractable Tinnitus

Hearing DisordersHearing Loss2 more

The purpose of this study is to determine whether chronic electrical stimulation of the primary auditory cortex is effective in the treatment of chronic, severe and intractable tinnitus

Completed7 enrollment criteria

The EarLens System Long Term Safety and Efficacy Definitive Multi-Center Study

Hearing Impairment

The EarLens System is an assistive hearing device that is intended to provide amplification for the treatment of patients with sensorineural hearing impairment. The purpose of this multi-center definitive study is to assess the safety and efficacy of the EarLens System for subjects with bilateral mild to severe sensorineural hearing impairments wearing the fully activated system in their daily lives for a 4 month period of time. This study is designed to support US and International marketing applications to commercialize the EarLens System. The main efficacy hypothesis is that the EarLens System will be shown to improve speech understanding in quiet.

Completed16 enrollment criteria

Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus...

Hearing LossSensorineural Hearing Loss1 more

This study is a single-center, randomized, placebo-controlled, double-blind, single ascending dose escalation study to determine the safety, tolerability, and PK profile of oral administration of HPN-07 in single doses to approximately 32 healthy male and female subjects between 18 and 55 years of age. Subjects will receive single oral doses of the study drug. The primary endpoint of this trial is to establish the safety and tolerability of HPN-07 and HPN-07 plus N-acetylcysteine (NAC).

Completed30 enrollment criteria

Blast Exposed Veterans With Auditory Complaints

Hearing ImpairmentHearing Aid Fitting

The purpose of this study is to study blast-exposed Veterans who report hearing handicap but show normal or near normal results on standard audiometric testing. The characteristics and nature of their auditory and auditory-related skills will be examined, along with whether coexisting PTSD contributes to the hearing problems of these Veterans. In a preliminary treatment study, a sub-sample of these Veterans will be fitted with mild-gain hearing aids to determine if they benefit from low-level amplification of high-frequency sounds.

Completed13 enrollment criteria

Clinical Applications for Time-Compressed Speech Tests

Hearing Loss

The purpose of this study is to determine the effects of age-related cognitive changes on hearing aid benefit based on hearing aid compression time constants. The hypothesis is that people with poor working memory skills will benefit from slow time constants in hearing aid compression while those with good working memory skills will be able to benefit from more sophisticated compression algorithms with rapid time constants.

Completed6 enrollment criteria
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