![Andrea Vambutas](https://trials-media.s3.amazonaws.com/orgs/andrea-vambutas.jpeg)
A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease
Sensorineural Hearing LossAutoimmune Inner Ear DiseaseThe purpose of this study is to determine if Anakinra (an interleukin-1 receptor antagonist) can improve hearing thresholds in those patients with Autoimmune Inner Ear Disease (AIED) that did not respond to oral steroid therapy for a sudden decline in hearing. The patients to be enrolled will have recently completed a course of oral steroids and demonstrated no change in their audiometric thresholds following corticosteroid therapy.
![University of Oklahoma](https://trials-media.s3.amazonaws.com/orgs/university-of-oklahoma.jpeg)
Balance in Children With Cochlear Implants
SevereProfound DeafnessThe purpose is to test the balance of children with unilateral,bilateral cochlear implants and patients having unilateral implants before,bilateral implants after surgery,using the Bruininks-Oseretsky Test 2nd ed. to find out if the cochlear implants have an effect.
![Erchonia Corporation](https://trials-media.s3.amazonaws.com/orgs/erchonia-corporation.jpeg)
Study of Low Level Laser Therapy and Word Recognition in Hearing Impaired Individuals
Sensorineural Hearing LossThe purpose of this clinical study is to determine the effectiveness of low level laser light therapy when applied around the head and ears in improving unaided word recognition in ears with sensorineural hearing loss.
![Hospital Clinic of Barcelona](https://trials-media.s3.amazonaws.com/orgs/hospital-clinic-of-barcelona.jpeg)
Chlorobutanol, Potassium Carbonate, and Irrigation in Cerumen Removal
Ear InfectionHearing Loss1 moreAccumulation of cerumen in the external ear canal is a common problem. The presence of cerumen not only interferes with the clinician's view of the tympanic membrane, but may also result in hearing loss and vertigo, and may predispose to ear infections. Removal of cerumen is facilitated by the use of a variety of ceruminolytics, or wax solvents. The current study was designed to evaluate the ceruminolytic effects of a single, brief application of the two most frequently used products in the investigators area, containing chlorobutanol or potassium carbonate with or without irrigation in the primary care setting in a randomized, single-blind trial. To our knowledge, this is the first randomized study comparing ceruminolytics with chlorobutanol versus potassium carbonate.
![University Hospital, Bordeaux](https://trials-media.s3.amazonaws.com/orgs/university-hospital-bordeaux.jpeg)
Chronic Electrical Stimulation of the Auditory Cortex for Intractable Tinnitus
Hearing DisordersHearing Loss2 moreThe purpose of this study is to determine whether chronic electrical stimulation of the primary auditory cortex is effective in the treatment of chronic, severe and intractable tinnitus
![VA Office of Research and Development](https://trials-media.s3.amazonaws.com/orgs/va-office-of-research-and-development.jpeg)
A Simplified Patient-Centered Educational Tool for Improved Hearing-Aid Outcomes
Hearing LossHearing loss is the second most prevalent service-connected disability among Veterans. Hearing aids are the most common technological intervention for hearing loss. The VA, therefore, spends a considerable amount of money on them. Despite these expenditures, there are some Veterans who do not use their hearing aids successfully. Research has demonstrated that this inconsistent use may be related to a patient's inability to effectively take care of, and use, hearing aids. The proposed investigation will compare the effectiveness of three different tools for enhancing the educational efforts (hearing-aid orientation) typically provided by clinical audiologists when dispensing hearing aids. Each of these educational tools were developed using established methods for improving patient-provider communication. The investigators hypothesize that the use of these tools will result in better hearing-aid outcomes for Veteran patients than using the current standard-of-care procedures.
![Indiana University](https://trials-media.s3.amazonaws.com/orgs/indiana-university.jpeg)
At-home Auditory Training Clinical Trial
PresbycusisAging1 moreThe purpose of this study is to investigate the effectiveness of an auditory training program used at home with the subject's own hearing aids.
![EarLens Corporation](https://trials-media.s3.amazonaws.com/orgs/earlens-corporation.jpeg)
The EarLens System Long Term Safety and Efficacy Definitive Multi-Center Study
Hearing ImpairmentThe EarLens System is an assistive hearing device that is intended to provide amplification for the treatment of patients with sensorineural hearing impairment. The purpose of this multi-center definitive study is to assess the safety and efficacy of the EarLens System for subjects with bilateral mild to severe sensorineural hearing impairments wearing the fully activated system in their daily lives for a 4 month period of time. This study is designed to support US and International marketing applications to commercialize the EarLens System. The main efficacy hypothesis is that the EarLens System will be shown to improve speech understanding in quiet.
![Cochlear](https://trials-media.s3.amazonaws.com/orgs/cochlear.jpeg)
Nucleus Hybrid L24 Extended Duration Post Approval Study
Hearing LossThis post approval study evaluates the long term safety and efficacy of the Nucleus Hybrid L24 Implant System in a group of already implanted recipients.
![Otologic Pharmaceutics, Inc.](https://trials-media.s3.amazonaws.com/orgs/otologic-pharmaceutics-inc.jpeg)
Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus...
Hearing LossSensorineural Hearing Loss1 moreThis study is a single-center, randomized, placebo-controlled, double-blind, single ascending dose escalation study to determine the safety, tolerability, and PK profile of oral administration of HPN-07 in single doses to approximately 32 healthy male and female subjects between 18 and 55 years of age. Subjects will receive single oral doses of the study drug. The primary endpoint of this trial is to establish the safety and tolerability of HPN-07 and HPN-07 plus N-acetylcysteine (NAC).