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Active clinical trials for "Heart Defects, Congenital"

Results 781-790 of 806

Northwest Adult Congenital Heart Disease Observatory

Congenital Heart Disease

The incidence of congenital heart disease is about 8 per thousand live births. Thanks to advances in cardiac surgery, 90% of children born with heart defects reach adolescence and adulthood. Congenital heart defects are the leading cause of heart disease in young adults and expectant mothers in Western countries. The number of patients increases continuously as life expectancy increases. An increasing number of patients with complex heart defects survive to adulthood. The medico-surgical management of this highly specialized growing number of patients is difficult and requires a multidisciplinary collaboration. In France, an estimated 200,000 patients the number of carrier patients with congenital heart disease. Half of them will require monitoring, medical procedures, catheterizations and/or surgical re-intervention. No objective demographic data are currently available on the French patients. So, the investigators decided to set up an epidemiological project to better understand this cohort of patients. The main objective of this project is to obtain accurate epidemiological data needed to adapt the supply of care.

Unknown status4 enrollment criteria

Thyroid Functions in Children With Congenital Heart Diseases

Value of Thyroid Functions in Children With Congenital Heart Diseases

Thyroid hormone is critical for normal neurocognitive development in young infants, and even transient hypothyroidism can cause adverse neurodevelopmental outcomes. In a population of infants with CHD who already bear a high risk of long-term developmental delay, detection of hypothyroidism, even of a transient nature, may be even more consequential, and routine periodic monitoring of thyroid function may be necessary to reduce the risk of neurodevelopmental disabilities

Unknown status2 enrollment criteria

Cardio Pulmonary Exercise Testing in Patients Post the Fontan Palliation in Comparison With Patients...

Fontan PalliationCongenital Heart Disease

prospective cardio respiratory evaluation for patients post the Fontan palliation for single ventricle, compared to subjects post successful cardiac repaired surgery compared to healthy volunteers in order to evaluate the functional capacity and the primary etiology for reduction in functional capacity.

Unknown status6 enrollment criteria

Using Near-infrared Spectroscopy (NIRS) Monitor to Noninvasively Evaluate Hepatic Venous Saturation...

Congenital Heart DiseaseArrhythmia

Clinical studies are required to validate the hepatic NIRS monitor with other regional and global hemodynamic parameters and to evaluate its clinical use for continuous non-invasive hemodynamic monitoring. Using newer NIRS sensors the correlation between hepatic regional oxygen saturation and hepatic venous oxygen saturation (SvHO2) needs to be determined. If found to correlate then the NIRS can be used to evaluate early liver transplant failure and/or hepatic artery thrombosis, used as an early marker for shock, and necrotizing enterocolitis, and finally used in the outpatient setting to evaluate patients with chronic liver pathologies. If our validation study finds that NIRS monitors are an appropriate marker of hepatic venous saturation then it will lead to further clinical studies.

Unknown status4 enrollment criteria

Acute Kidney Injury After Cardiac Surgery on CPB

Acute Kidney InjuryCongenital Heart Disease4 more

The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne, Switzerland.

Unknown status3 enrollment criteria

The Application Value of STIC in the Diagnosis of Fetal Complex Congenital Heart Disease

Congenital Heart Disease

The objective of this study is to use of STIC technology to assist the traditional echocardiography to diagnose the fetal congenital heart disease accurately and then to provide a basis for prenatal counseling.

Unknown status8 enrollment criteria

Improvement on Diagnosis of Fetal Congenital Heart Disease Based on Multi-center Collaboration in...

Congenital Heart DiseaseEchocardiography1 more

The objective of this study is to improve the diagnosis level of fetal congenital heart disease by the multi-center collaboration in China.

Unknown status5 enrollment criteria

Aortic Valve Leaflets Reconstruction (Ozaki Procedure) in Aortic Valve Diseases

Aortic Valve Disease

Prospective Cohort Study aims at elaborating the outcomes of the Tricuspid Reconstruction of Aortic valve leaflets using autologous pericardium (Ozaki procedure) in the adult and paediatric patients. A very promising technique with the potential benefits of dodging oral anticoagulation, foreign material, and suitable for patients with small aortic annuli and in infectious endocarditis. Performing hemodynamic evaluation, assess the clinical implementation and report preliminary results at follow up .

Unknown status9 enrollment criteria

Fetal Cardiac Magnetic Resonance in Detection of CHD

Congenital Heart DiseaseFetal Cardiac Disorder2 more

The aim of this clinical prospective study is to investigate the value of fetal cardiac magnetic resonance imaging using a new Doppler ultrasound based gating method for the detection of congenital heart desease.

Unknown status3 enrollment criteria

Evaluation of the Diagnostic Performance of Specialized Fetal Cardiac Ultrasound in the CPDPN -...

Heart DefectsCongenital2 more

To evaluate the diagnostic performance of antenatal echocardiography with regard to the main diagnosis of heart disease made by cardio-pediatricians at the couple-child hospital in Grenoble according to the ACC-CHD classification, in pregnant women who have had a fetal heart ultrasound between 2015 and 2019. *ACC-CHD : Anatomic and Clinical Classification of Congenital Heart Defects

Unknown status2 enrollment criteria
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