Clinical and Genetic Characteristics of Coronary Artery Disease in Chinese Young Adults
Coronary Artery DiseasePercutaneous Coronary InterventionThe aim of this study is to identify genetic loci,or gene variations contributing to the development of coronary artery disease (CAD) in Chinese young adults. Investigators will compare coronary angiogram results to genetic findings within young CAD patients.
Long-term Outcome of Triple-vessel Coronary Artery Disease Underwent Three Different Strategies...
Coronary Artery DiseaseCoronary Stenosis1 moreThe study is to determine the long-term outcome of patients with coronary triple vessels disease (TVD) in the real world of China, by three different treatment strategies: percutaneous coronary intervention (PCI), Coronary artery bypass graft (CABG) or optimal medication therapy (OMT).
Mechanisms of Myocardial Infarction in Women With Non Obstructive Coronary Artery Disease
Myocardial InfarctionThe objective of our work to determine the mechanisms of myocardial infarction in women without obstructive coronary artery disease.
Assessment of Functional Capacity and Inflammatory Markers in Women With Heart Failure With Preserved...
Heart FailureDiastolic2 moreThis study assesses the impact of diastolic heart failure on exercise capacity in women who have a previous coronary condition. All the participants will go through the same evaluation.
Myovista iECG for Detecting Ischemic Heart Disease: Comparison With Computed Tomography Coronary...
Coronary Artery DiseaseStudy evaluates the new technique MyoVista™ iECG sensitivity and ability to predict myocardial diseases, comparing iECG results with Computed Tomography Coronary Angiography findings
Typical Daily Experiences, Ischemia and Repolarization in Coronary Artery Disease
Coronary Artery DiseaseBehavioralThe purpose of this study is to examine the role of every day experiences as they relate to coronary artery disease (CAD).
Role of the Inflammatory Receptors in the Pathogenesis of Atherosclerosis
Coronary Artery DiseaseThe primary objective of this study is to assess whether inflammatory receptors play a role in the pathogenesis of atherosclerosis.
MRI Perfusion Imaging at 3Tx Compared to Invasive FFR Measurements
Perfusion ImagingMRI2 moreCoronary artery disease (CAD) has a great significance concerning prevalence and mortality in the western world. It is usually diagnosed by catheterization and coronary arteries are visually assessed by the examiner. Thus having a great spectrum of interobserver differences, especially when it comes to intermediate lesions. The gold standard to assess the haemodynamic significance is the measurement of the myocardial fractional flow reserve (FFR). The FAME-study (Tonino, De Bruyne et al. 2009) was able o show that additional FFR- measurements in patients with intermediate lesions could significantly reduce stent implementation and consequently mortality. However this method is not used in daily routine and is available only in a fraction of catheter labs worldwide. Taking this into account decision finding especially in intermediate lesions remains difficult. One major step to simplify the invasive approach concerning intermediate lesions would be to establish a non-invasive procedures which localizes the coronary vessel to intervene ahead catheterization. Do to steady technical development cardiac MRI has become a powerful tool which is able to determine myocardial vitality, perfusion and function. In particular the new generation of 3 Tesla multi transmit MR with its higher field strength and better spatial resolution seems to be able to show first pass myocardial perfusion more precise. With this new technology prefixed to cardiac catheterization clinical relevant information can be made accessible and thus reduce the number of unnecessary implemented stents.
Transluminal Attenuation Gradient Versus CT Fractional Flow Reserve
Coronary Artery DiseaseCoronary computed tomographic angiography (CCTA) has emerged as a non-invasive test, accurately evaluate anatomic coronary artery stenosis. However, anatomically-obstructive coronary stenosis by CCTA demonstrates an unreliable relationship to lesion-specific ischemia. Recently, with the advance of imaging reconstruction and analysis technique, several novel parameters computed from CCTA were suggested to have added value in determining the ischemia-causing coronary stenosis. In this study, diagnostic performance of transluminal attenuation gradient (TAG) and fractional flow reserve computed form CCTA (FFR-CCTA) for the presence of hemodynamically-significant coronary stenosis, as determined by fractional flow reserve (FFR).
Subclinical COronary Atheroscleorosis Updated With Coronary cT Angiography (SCOUT Study)
Coronary AtherosclerosisThe purpose of this study is to validate the usefulness of 64-slice multi-detecter computeted tomography as a screening tool in asymptomatic population.