
Serum Sex Hormone Levels and Subclinical Atherosclerosis - Ancillary to MESA
Cardiovascular DiseasesAtherosclerosis3 moreTo assess the associations of serum sex hormones with the presence and progression of subclinical atherosclerosis.

Dietary Fatty Acids, PPAR Activated Genes, and CHD
Coronary DiseaseCardiovascular Diseases2 moreTo examine the relationship between genetic and dietary factors that modify the risk of coronary heart disease (CHD).

Ventricular Size and Value Calcification Measures by Computed Tomography - Ancillary to MESA
Cardiovascular DiseasesHeart Diseases2 moreTo rescan 6,700 subjects in the MESA study to obtain computed tomography measures of calcification.

VLDL and LDL Particle Types as Coronary Heart Disease Risk Factors
Cardiovascular DiseasesHeart Diseases5 moreTo evaluate very low density lipoprotein (VLDL) and low density lipoprotein (LDL) particle types as predictors of initial coronary events.

Angiotensinogen Gene and Human Hypertension
Cardiovascular DiseasesHeart Diseases1 moreTo determine the role of the angiotensinogen gene in human hypertension.

Soy Food and Coronary Heart Disease in Women
Cardiovascular DiseasesCoronary Disease1 moreTo investigate whether soy food intake reduces risk of non-fatal myocardial infarction (MI) and fatal coronary heart disease in Chinese women.

Heavy Metals, Obesity and Cardiovascular Risk - Ancillary to Look AHEAD
Diabetes MellitusNon-insulin Dependent5 moreTo evaluate the relationship of baseline toenail chromium concentrations to weight loss, as well as the interaction between heavy metals and the beneficial effects of weight loss.

Neighborhood-Level Influences on All-Cause Mortality
Cardiovascular DiseasesHeart DiseasesTo test the independent and interrelated effects of the neighborhood social environment, the neighborhood physical environment, and individual risk factors in predicting all-cause and cardiovascular disease mortality.

Cardiovascular Vulnerability to Particulate Exposure
Heart DiseaseLung DiseaseThis project is part of a program project directed toward assessing cardiac effects of particulate and other ambient air pollutants. In this project active elderly adults living in the communities of Boston and Steubenville have attended 12 weekly sessions including approximately 40 minutes of Holter monitoring, blood pressure, and oximetry evaluation before, during, and after outdoor exercise. To investigate the relation of air pollution to cardiac and pulmonary rehabilitation, a second portion of this study involves abstraction of blood pressure and symptom data and downloading of available repeated measures telemetry data in two populations. These populations include: 1) 200 outpatients attending 8 to 36 repeated weekly exercise training sessions in a major hospital cardiac rehabilitation unit.

Cardiac Vulnerability in Potentially Susceptible Patients
Heart DiseaseThis project is part of a program project directed toward assessing cardiac effects of particulate and other ambient air pollutants. In this project patient who have recently suffered a cardiac event are being monitored with cardiac monitors for 24 hours up to 4 times during the year following their cardiac event. Similarly a second group of patients with moderate to severe heart failure will undergo similar cardiac monitoring for 24 hours, twice a week separated by 3 months. In both sets of patients home indoor pollution measures will be continuously made and used to correlate with measures of heart rate variability.