
Genetic Epidemiology of CHD Risk Factors in Blacks
Cardiovascular DiseasesHeart Diseases1 moreTo determine the genetic epidemiology of coronary heart disease (CHD) risk factors in Blacks.

Epidemiology of Long QTand Asian Sudden Death in Sleep
Cardiovascular DiseasesHeart Diseases5 moreTo conduct a cross-sectional epidemiologic study of the determinants of prolonged heart rate corrected QT interval (QTc) among 300 men and 300 woman in the population with the highest known risk of SUDS: Southeast Asian refugees in Thailand. .

Smoking Onset in a Biethnic Population
Cardiovascular DiseasesHeart Diseases1 moreTo conduct a prospective study of the determinants of smoking onset in adolescents attending Memphis City Schools and to determine the unique predictors of smoking onset in Black versus white adolescent females.

Insulin, Androgen, and Risk in African-American Women
Cardiovascular DiseasesDiabetes Mellitus4 moreTo distinguish whether the observed gender differences in plasma insulin and insulin resistance reflect biologic differences, or whether the gender differences in insulinemia are determined by greater adiposity in women. Also, to determine if the hyperinsulinemia per se contributes to excess risk for cardiovascular disease in African American women. Finally, since higher androgenicity is linked with cardiovascular risk in women, to determine if the risk factors associated with hyperinsulinemia are modulated by sex hormones.

Epidemiology of Carotid Artery Atherosclerosis in Youth
AtherosclerosisCardiovascular Diseases2 moreTo examine the relationship of risk factors measured in childhood to intimal medial thickness (IMT) in early adulthood and to examine familial factors which may be related to increased IMT, a measure of atherosclerosis.

Cohort Study of Heart Rate Variability
Cardiovascular DiseasesMyocardial Ischemia4 moreTo examine factors affecting heart rate variability (HRV) and the role of HRV in heart disease. Specifically, to examine the role of HRV: as a predictor of fatal and nonfatal ischemic heart disease over a six year follow-up of the Atherosclerosis Risk in Communities (ARIC) population based, bi-ethnic cohort; on the six year progression of carotid atherosclerosis measured by B-mode ultrasound; and on the incidence of hypertension. Also, to study the effect of elevated fasting insulin, glucose, diabetes mellitus, and other metabolic abnormalities on changes in HRV over nine years of follow-up.

Parity and Serum Lipids in White and Hispanic Women
AtherosclerosisCardiovascular Diseases1 moreTo analyze the relationships between parity (childbirth) or gravidity (pregnancy) and measures of lipids in groups of women from the Hispanic Health and Nutrition Examination Survey (Hispanic HANES) and the Framingham Heart Study.

Reanalysis of CVD Risk Factors Via Likelihood Methods
Cardiovascular DiseasesHeart Diseases1 moreTo reanalyze data on risk factors for cardiovascular disease (CVD) including total cholesterol and high density lipoprotein (HDL) cholesterol for the subjects in the first, second, and third exams of the NHLBI Twin Study.

Study of Children's Activity and Nutrition (SCAN)--Extended Analyses
Cardiovascular DiseasesHeart Diseases1 moreTo continue analysis of data from a longitudinal study of 246 urban Black preschool children and their families in order to identify the long-term effects of social and environmental influences on nutrition and activity and the consequences of these influences for the children's cardiovascular disease (CVD) risk status.

Epidemiology of Cardiotoxicity in Children With Cancer
Cardiovascular DiseasesHeart Diseases6 moreTo provide a comprehensive analysis of risk factors for the development of clinical cardiotoxicities in over 6,000 children with cancer who had been treated on standardized protocols involving the use of anthracyclines alone or in combination with other potentially cardiotoxic therapies or with no use of anthracycline therapy.