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Active clinical trials for "Heart Diseases"

Results 3451-3460 of 3529

Prenatal Screening for Congenital Heart Diseases in the Antwerp Region

Congenital Heart Disease in Pregnancy

No systematic research has been done in the last 15 years on the accuracy of prenatal ultrasound of congenital heart diseases in Belgium. Nor are there any population-based studies available on this subject for Belgium. Based on the data of EUROCAT (European Surveillance of Congenital Anomalies) the investigators analyse prenatal diagnostic sensitivity of congenital heart diseases in the EUROCAT regions Antwerp (Flanders, Belgium)

Unknown status5 enrollment criteria

Impact of Arterial Cannulation Site on Vasopressor Requirement in Cardiac Surgery

Cardiac Disease

Choice of arterial cannulation site during cardiac surgery is controversial. Some physicians in our institution prefer radial artery site, others prefer aortic site (via femoral artery or brachial artery). The investigators aim to compare these two strategies for vasopressor requirement. The study hypothesis is that radial artery cannulation is associated with a larger dose of vasopressor due aortic to radial arterial pressure gradient phenomenon.

Unknown status3 enrollment criteria

Plasma Metanephrines in Patients With Cyanotic and Acyanotic Congenital Heart Disease

Acyanotic Congenital Heart DiseaseCyanotic Congenital Heart Disease2 more

The aim of our study is to compare plasma metanephrines in patients with cyanotic and acyanotic congenital heart disease and possible association with chronic hypoxic stress.

Unknown status2 enrollment criteria

Copeptin and HFABP in Cardiac Surgery

Coronary Artery DiseaseValvular Heart Disease

In-hospital mortality after cardiac surgery ranges from 2-6%. Many patients suffer from major adverse cardiovascular events (MACE) which results in impaired disability-free survival. Troponin plays the central role in identifying MACE. However, interpretation after cardiac surgery is difficult due to ischemia-reperfusion-injury and direct surgical trauma. While the 4th universal definition of type 5 myocardial infarction uses the 10 x ULN as cut-off, >90% of patients after on-pump procedures exceed this cut-off. Clinical consequences are unclear. The dynamic of Copeptin and Heart-type fatty acid binding protein (H-FABP) concentrations starts very early, i.e. several hours before Troponin. The investigators plan a prospective multicenter cohort study to evaluate 1) the independent association between Copeptin and H-FABP with disability -free survival and MACE after cardiac surgery; 2) the predictive gain of their addition to the Euroscore II; 3) the independent association between H-FABP and acute kidney injury.

Unknown status10 enrollment criteria

Heart and Ischemic STrOke Relationship studY

Brain IschemiaAcute Stroke1 more

Although cardio-embolic etiology of ischemic stroke (IS) is largely respected, there is still no clear recommendation for routine complex cardiological examination in all IS patients. Using complex cardiological examination the investigators expect: more accurate detection of patients with concomitant heart disease (cardiac rhythm disorder, valve disorders, acute coronary syndrome, cardiac thrombus and myxoma, atrial and ventricle septum defects) higher number of etiologically determinated IS, which is crucial for accurate secondary prevention.

Unknown status2 enrollment criteria

Trial to Assess the Everolimus-Eluting Coronary Stent System (PROMUS Element) for Coronary Revascularization...

Ischemic Heart DiseaseCoronary Artery Stenosis

The PROMUS Element™ clinical trial (PLATINUM-PLUS) consists of a randomized controlled trial (RCT) in the European Union (EU) which will enroll approximately 2980 subjects (2:1 randomization PROMUS Element™: Xience™ Prime) in a Population of consecutive, all comers in the reimbursed indications per-country All subjects will be screened per the protocol required inclusion/exclusion criteria.

Unknown status17 enrollment criteria

Case-Control Study of Fibrotic Interstitial Lung Disease (ILD) and Cardiac Disease / Interventions....

Idiopathic Pulmonary FibrosisInterstitial Pneumonia

There is a rare condition causing scarring of the lungs termed interstitial lung disease. This comprises a group of conditions which can be divided into separate diseases. The aim of this study is compare a group of patients (the cases) with 2 types of this disease (fibrotic non-specific interstitial pneumonia (NSIP) and idiopathic pulmonary fibrosis (IPF)) with patients without the disease. The study will look at the 2 groups and their exposures to factors such as medications, smoking, previous jobs, previous medical problems and specifically heart disease and any operations or procedures involving the heart. There have been previous studies showing a link between heart disease and scarring of the lungs. This study will look at whether this association is stronger in one or the other type of lung scarring diseases.

Unknown status2 enrollment criteria

After Eighty Study

Coronary Heart Disease

The rationale of the present clinical trial is to study whether an invasive strategy in clinical stable patients over 80 years with NSTEMI/UAP may improve rates of death, reinfarction, stroke, need of urgent revascularisation, myocardial function and quality of life. The invasive approach involves coronary angiography with immediate evaluation for three different treatment options; 1. Percutaneous coronary intervention (PCI), 2. Coronary artery bypass graft (CABG) or 3. medical treatment. Clinical practice shows that older patients are commonly treated less vigorously than younger patients and the present guidelines are based on a considerably younger population.

Unknown status10 enrollment criteria

Role of Chest Ultrasound in Detection of Post-operative Pulmonary Complications After Cardiothoracic...

IHDValve Heart Disease1 more

assess feasibility of detecting pulmonary complications postoperative using chest ultrasound compared to chest x-ray measure time lag between using ultrasound and using chest x-ray to detect pulmonary complications postoperative

Unknown status5 enrollment criteria

Prevalence of Oral Mucosal Alterations In a Sample of Egyptian Patients With Cardiovascular Diseases:...

Cardiac Disease

to assess the oral mucosal alterations and their prevalence secondary to use cardiovascular drugs in a sample of Egyptian population with cardiovascular diseases .

Unknown status4 enrollment criteria
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