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Active clinical trials for "Heart Diseases"

Results 901-910 of 3529

Niacin Plus Statin to Prevent Vascular Events

Cardiovascular DiseasesHeart Diseases4 more

The purpose of this study is to determine whether raising "good cholesterol" with a drug based on the vitamin niacin, while lowering "bad cholesterol" with a statin drug, can prevent more heart disease than the statin alone.

Terminated10 enrollment criteria

The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic...

Heart DiseaseCardiovascular Disease

A growing body of evidence links Chlamydia pneumoniae to the progression of coronary heart disease. The purpose of this study is to determine the positive and negative effect of 14 days treatment with clarithromycin 500 mg daily in patients already suffering from stable coronary heart disease. The participants will be followed for at least two years after the treatment. Abbott Laboratories supplied Clarithromycin and placebo tablets.

Completed17 enrollment criteria

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)...

HypercholesterolemiaCoronary Disease

The purpose of this study is to investigate additional cholesterol lowering effects in patients with coronary heart disease by giving an investigational drug with a patient's current approved cholesterol lowering medication.

Completed2 enrollment criteria

Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery

Coronary DiseaseHeart Diseases2 more

The purpose of this study is to examine the effects of supplemental magnesium on the neurocognitive function of individuals undergoing coronary artery bypass graft (CABG) surgery.

Completed3 enrollment criteria

Optimum Platelet Inhibition After Coronary Bypass Surgery

Ischemic Heart Disease

To investigate the effect of different dosages of aspirin on platelet aggregation and to determine the possible mechanisms of aspirin resistance, we intend to compare the effects of low, medium dose aspirin with clopidogrel (an alternative antiplatelet agent) in patients after coronary artery bypass surgery.

Completed19 enrollment criteria

A Phase II Optimization Study of BMS068645 and Sestamibi Planar Imaging

Cardiovascular DiseaseIschemic Heart Disease

The primary purpose of this study is to determine the optimal time for myocardial perfusion imaging with Technetium Tc99m Sestamibi following the administration of BMS068645. The safety of BMS068645 will also be studied.

Terminated7 enrollment criteria

Physician Uncertainty Reduction for Hypertension

Cardiovascular DiseasesHeart Diseases1 more

The purpose of this study is to test the theory that a major factor in poor blood pressure (BP) control is that physicians fail to intensify antihypertensive therapy for their patients.

Completed8 enrollment criteria

Effects of Optimized Antiplatelet Treatment After Percutaneous Coronary Intervention

Ischemic Heart DiseaseAcute Coronary Syndromes

Effects of dual antiplatelet therapy with aspirin and clopidogrel after percutaneous coronary intervention has been proven. However, patients with low response to those agents are reported be associated with adverse clinical outcomes. We suppose that optimized antiplatelet therapy for individual patients based on platelet function assay may improve long-term outcomes especially in patients with high risk of thrombosis. In this prospective randomized study, patients in control group all receive standard dual antiplatelet therapy, and patients in optimized group receive different antiplatelet therapy according to risk stratification.

Completed8 enrollment criteria

Enalapril After Anthracycline Cardiotoxicity

Cardiovascular DiseasesHeart Diseases2 more

To determine if the chronic administration of enalapril, an inhibitor of angiotensin converting enzyme (ACE), reduces progression of cardiac dysfunction in pediatric oncology patients who have received anthracyclines, and who are not currently on digoxin, diuretics, or vasodilators for heart failure.

Completed1 enrollment criteria

Rapid Early Action for Coronary Treatment (REACT)

Cardiovascular DiseasesCoronary Disease3 more

To evaluate the impact of community educational interventions on patient delay time from onset of symptoms and signs of an acute myocardial infarction (AMI) to arrival at a hospital Emergency Department (ED). Also, to study the impact of community educational interventions on use of Emergency Medical Services (EMS) and EDs, on thrombolytic therapy, and on AMI case fatality.

Completed1 enrollment criteria
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