Continuous Lenalidomide Therapy Versus Observation Following Induction Without Lenalidomide, Pomalidomide...
Multiple MyelomaNeoplasms5 moreThe purpose of this study is to see how long lenalidomide therapy can maintain or improve the disease response obtained after induction therapy that does not include lenalidomide, pomalidomide or thalidomide; and consequently reduce worsening of disease and to evaluate the activity of lenalidomide. Patients will receive lenalidomide or be under observation. All patients will attend regular clinic visits to evaluate their disease and health. Patients will have the option to participate in additional biomarker correlative studies in addition to their participation in the main study.
Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia
Hematologic DiseasesAnemia1 moreThe purpose of this study is to determine if hydroxyurea therapy is effective in the prevention of chronic end organ damage in pediatric patients with sickle cell anemia.
Hematological Abnormalities in Children
Hematologic Diseasesthe aim of the study is to determine Hematological abnormalities in Congenital Cyanotic Heart Disease
Collection of Peripheral Blood Mononuclear Cells From Healthy Subjects
Disease of the BloodIn accordance with the selection criteria, component blood collection will be carried out and peripheral blood mononuclear cells will be isolated, cryopreserved and in vitro culture of peripheral blood mononuclear cells. Cultivating cells under normal culture conditions or potential drug molecule treatment, observing and recording key parameters such as cell viability, proliferation, apoptosis and functional gene expression, will also provide an important reference for the production of CAR-T cell drugs.
The Evaluation of Anti-interference Ability and Clinical Specificity of HIV Ag +Ab Assay Kit (Sysmex)...
HIV SeropositivityCancer1 moreTo evaluate the anti-interference and specificity of HIV Ag +Ab Assay Kit (Sysmex) for the detection of HIV antigens and antibodies.
Spectrum of Hematological Disorders in Pediatrics
PancytopeniaTo determine the spectrum of pancytopenia with its frequency and etiology in children presenting to Assiut University Children Hospital during one year
QIAstat-Dx® BCID Plus AMR Panels Clinical Performance Study
Blood DiseaseStudy for performance evaluation of the QIAstat-Dx® BCID Plus AMR GPF-Panel and the QIAstat Dx® BCID Plus AMR GN-Panel in comparison with other chosen comparator methods
Clonal Hematopoiesis of Immunological Significance
Immune System DiseasesAutoimmune Diseases14 moreAmbispective, national, multicenter observational cohort study aimed at characterizing the satellite dysimmune manifestations of clonal hematopoiesis, including Vexas (Vacuoles, E1 enzyme, X-linked, Autoinflammatory and Somatic) syndrome.
Hematological Disorder in Patients With Angiodysplasia
AngiodysplasiaHematological DiseaseThe study aim will be to assess the association between GIT angiodysplasia with any hematological disorders such as any specific coagulation disorders or anemia.
Hematological Disorders in Covid 19 Patients
Hematological Abnormalities in covid19aim of the research is to detect hematological abnormalities in covid 19 patients and its correlation with the severity and outcome of the disease.