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Active clinical trials for "Liver Cirrhosis"

Results 741-750 of 1394

The Effects of the Anhepatic Phase Extended by Temporary Portocaval Shunt on Anesthetic Sensitivity...

Liver Cirrhoses

This study aims to investigate the effects of the anhepatic phase extended by temporary portocaval shunt on the sensitivity to desflurane administered at 0.6 age-adjusted minimum alveolar concentration and its associative postoperative cognitive function.

Completed11 enrollment criteria

Proton Pump Inhibitors and Dysbiosis in Cirrhosis

CirrhosisHealthy

The purpose of this study is to find out whether the use of medications that suppress acid in your stomach can change the composition of your bowel bacteria.

Completed12 enrollment criteria

Acoustic Radiation Force Impulse-Imaging in Comparison to Transient Elastography for Liver Fibrosis...

Chronic Hepatitis C

This study will evaluate the effectiveness of Acoustic Radiation Force Impulse (ARFI)- Imaging compared to Transient Elastography (FibroScan) in differentiating liver fibrosis in patients with chronic hepatitis C. Patients who are scheduled to have a liver biopsy will also undergo ARFI and FibroScan testing. The liver biopsy will be used as the reference method. The target sample size is 433.

Completed11 enrollment criteria

Rifaximin Versus Lactulose in Renal Failure

Liver CirrhosisRenal Failure

The purpose of this study is to evaluate patients with cirrhosis of the liver and renal failure and determine if the administration of rifaximin as compared to lactulose is associated with less frequent and/or slower progression to severe hepatic encephalopathy. If one is associated with lower blood ammonia levels. And, if one is associated with lower breath hydrogen and methane levels.

Withdrawn4 enrollment criteria

Subclinical Myocardial Dysfunction in Patients With Hepatic Cirrhosis

CirrhosisCardiomyopathy

The prevalence of hepatic cirrhosis in Romania is very high, with a 10-year mortality of 34-66%. Upward trend of mortality is observed. It is known that cirrhosis is associated with cardiac abnormalities. These can induce several complications of cirrhosis, and increase postoperative mortality. Therefore, it is a major public health issue and research in this field should be a priority. Few studies evaluated the cardiac function in cirrhotic patients, using only conventional echocardiography. However, this allows only the late diagnosis of cardiac dysfunction, which might be already irreversible. Consequently, description of new parameters, which could detect early dysfunction, becomes essential. There is no study designed to estimate intrinsic myocardial properties in cirrhosis. New methods (Tissue Doppler and Speckle-tracking echocardiography) could be essential to detect early cardiac dysfunction. The exact role of biological markers in the diagnosis of cardiac dysfunction remains to be clarified. Impaired cardiac function coupled with augmented vascular function could be the model for cirrhotic patients. This type of ventriculo-arterial interaction has never been described. The main objectives of our project are: to investigate the mechanisms which lead to cardiac dysfunction; to describe new parameters for the early diagnosis of cirrhotic cardiomyopathy; to describe the type of ventriculo-arterial interaction; the association between biological markers and echo parameters.

Completed12 enrollment criteria

Probiotics for the Prevention of Major Complications of Cirrhosis

Liver Cirrhosis

The purpose of this study is to determine whether probiotics are effective in the prevention of the complications of liver cirrhosis.

Completed5 enrollment criteria

Global Research Initiative for Patients Screening on NASH

NASHNAFLD8 more

GRIP on NASH will assist primary care physicians and clinicians to implement the latest patient care pathway, as described by the European Association for the Study of the Liver (EASL), to identify patients at risk of severe fatty liver disease and to raise awareness on fatty liver disease. The primary objective is to implement a transmural patient care pathway, in order to identify patients with non-alcoholic fatty liver diseases (NAFLD) and its progressive form non-alcoholic steatohepatitis (NASH) in primary care centres and clinics in 10 European countries.

Not yet recruiting24 enrollment criteria

Platelets Indices and Its Role to Predict Liver Fibrosis in Patients With Chronic Hepatitis B Infection...

FibrosisLiver

Platelets indices and its role to predict liver Fibrosis in patients with chronic hepatitis B infection

Not yet recruiting3 enrollment criteria

Cirrhosis Readmission Telehealth Project

Cirrhosis

This is a 2 year research study to study if post discharge phone calls can help lengthen time to hospital readmissions for patients with encephalopathy.

Terminated19 enrollment criteria

Liver Fibrosis in Patients Transplanted for Hepatitis C Receiving Either Cyclosporine Microemulsion...

Liver TransplantHepatitis C

Following a transplant for hepatitis C cirrhosis, the infection comes back in 70-90% of cases and over time causes fibrosis and eventually cirrhosis of the new liver. The aim of this study was to see if the frequency of liver fibrosis was different with cyclosporine microemulsion than tacrolimus

Terminated9 enrollment criteria
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