Hepatitis B Virus Vertical Transmission From HIV-HBV Co-infected Women
Vertical Disease TransmissionHBVVertical HIV transmission has been dramatically reduced by the use of combined antiretroviral therapy in HIV-infected pregnant women. Among the most often used drugs, several have dual activity, against HIV and HBV: lamivudine, emtricitabine, tenofovir. Studies about vertical HBV transmission from HIV-HBV co-infected pregnant women are rare in developed countries. The study hypothesis is a major reduction of the risk of HBV vertical transmission.
A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis...
Hepatitis BChronicThis retrospective study will evaluate the association of biomarkers and the treatment response of patients with chronic hepatitis B, who have completed therapy with Pegasys (peginterferon alfa-2a) ± lamivudine. For the analysis stored serum samples obtained from patients will be used; no actual patients are involved.
Prospective Study In Noninvasive Evaluation of Hepatic Fibrosis in Chronic Hepatitis B
Chronic Hepatitis BThe aim of our study is to evaluate liver fibrosis using biochemical markers, FibroScan, and radiology methods in patients with chronic hepatitis B in mainland China.
Prospective Cohort Study of Association of Insulin Resistance/Steatosis With Hepatic Fibrosis in...
Chronic Hepatitis BHepatic Fibrosis1 moreHepatic steatosis and insulin resistance are associated with severity of fibrosis in non-alcoholic fatty liver disease (NAFLD) and chronic hepatitis C. However, clinical significance of steatosis and insulin resistance on fibrosis in chronic hepatitis B (CHB) is not well established. The aim was to investigate the relationship between insulin resistance, hepatic steatosis, and fibrosis in patients with CHB.
Risk of Hepatitis B Virus Reactivation in Patients Undergoing Allografting
Hepatitis B VirusAllograft1 moreThe purpose of this study is to evaluate the risk of hepatitis B reactivation in patients undergoing allografting.
Systematic Review of Antiretroviral Treatments for Chronic Hepatitis B (CHB)
Hepatitis BChronicThe purpose of this study is to support the clinical value of entecavir by assessing the relationship between viral load and histological improvement.
Evaluation of Chronic HBV Patients w/Evidence of HBV Replication and Normal or Minimally Elevated...
Chronic Hepatitis BTo determine whether HBeAg-positive and HBeAg-negative patients with HBV DNA greater than or less than 5 log10 and 4 log10 copies/mL, respectively, and with normal or minimally elevated liver transaminases have histological evidence of active liver disease.
Biomarkers Guided Stopping NAs Treatment
Chronic Hepatitis bThe primary objective of this study is to evaluate hepatitis B surface antigen (HBsAg) loss in subjects who stop nucles(t)ide analogues (NAs) (Stop arm) compared to subjects who continue (Continue arm) Only subjects who already are on treatment with ETV, TDF or TAF monotherapy, and have achieved sustained virologic suppression (<20 IU/mL), HBeAg negativity, normal ALT for more than 1 year (pretreatment HBeAg + pts) or 3 years (pretreatment HBeAg - pts), plus qHBsAg <200 IU/mL, and HBV RNA or HBcrAg negativity will be included in this study. One treatment arm will stop the NAs therapy while the other treatment arm will continue the NAs therapy. Participants in the Stop arm will be monitored very closely with special focus on clinical relapse. If any participant in the Stop NAs arm exceeds one or more predefined limits for such flares or relapses, NAs treatment will be reinstituted.
Baseline Investigation of Chronic Hepatitis B Viruses Infections: Who is Eligible for Treated Criteria...
Hepatitis BThrough two-stage stratified cluster sampling, investigators studied the antiviral treatment rate and the main factors affecting the antiviral treatment in community chronic HBV infection-related liver disease population.
Effects of Antiviral Therapy on Patients With HBV-related HCC
Hepatocellular CarcinomaHepatitis B Virus1 moreBased on the follow-up data of patients who underwent hepatectomy for HBV-related HCC at the First Affiliated Hospital of Xi'an Jiaotong University. patients who met the enrollment criteria were screened for tumor recurrence and survival for statistical analysis to understand the prognosis of patients and analyze the risk factors affecting their prognosis.