Study to Evaluate the Safety and Pharmacokinetics of Single Doses of ASP2151 in Healthy Male Subjects...
Herpes GenitalisHerpes ZosterThe objective of this study is to evaluate the safety and tolerability of single rising doses of ASP2151 under fasted condition in healthy male subjects. The study will also evaluate the pharmacokinetics (PK) of a single dose of ASP2151 under fasted versus fed conditions in healthy male subjects.
Acyclovir in Preventing Herpes Simplex Virus Infection in Patients With Neutropenia
Herpes SimplexRATIONALE: Acyclovir may be effective in preventing herpes simplex virus infection in patients with neutropenia. PURPOSE: This randomized phase III trial is studying the side effects of acyclovir and is comparing two doses of acyclovir in preventing herpes simplex virus infection in patients with neutropenia.
Age Differences in Influenza and Herpes Zoster Vaccine Responses (INFLUENZA-SHINGRIX)
InfluenzaHerpes ZosterVaccines are used to prevent infectious diseases worldwide. Unfortunately, many vaccines, like the flu vaccine, are less effective in older adults. This single-centre open label partially randomised, partially placebo-controlled trial evaluates the differences in immune response between young and older adults after vaccination with a quadrivalent inactivated influenza vaccine and an adjuvanted herpes zoster vaccination. Exploring the underlying mechanisms between the differences in immunogenicity can provide important information for future vaccine development.
Potential Influence of Pantoprazole on the Pharmacokinetics of Pritelivir
HSV InfectionTo investigate the effect of esomeprazole (ESO) on the pharmacokinetics of pritelivir (PTV), and to investigate the safety and tolerability of PTV.
Study to Evaluate Using a Cold Sore Patch to Treat Herpes Labialis
Herpes LabialisThe primary objective of this study was to evaluate the safety and performance of a cold sore patch for the treatment of herpes labialis.
Effectiveness and Clinical Mechanism of Huanglian-Jiedu Decoction in Patients With Intense-exuberant...
Intense-exuberant Stomach Fire SyndromAcute Pericoronitis2 moreThis clinical research focus on evaluating the effectiveness of Huanglian-Jiedu Decoction in patients with intense-exuberant stomach fire syndrome (one of the common TCM syndrome)of acute pericoronitis,minor recurrent aphthous stomatitis and recurrent herpes simplex labialis,meanwhile, exploring the pharmacological mechanism and potential biomarkers of this traditional formula.
Erector Spinae Block Versus Thoracic Paravertebral Block for Acute Thoracic Herpes Zoster
Acute Thoracic Herpes ZosterErector Spinae Plane Block2 moreThe aim of this research is to study and compare the efficacy and safety of single injection erector spinae plane block and thoracic paravertebral block in prevention of post herpetic neuralgia in patients with acute thoracic herpes zoster.
Study of a New Topical Natural Health Product for the Treatment of Herpes Labialis
Herpes LabialisThe aim of this study is to determine the safety and efficacy of a topical natural health product in comparison to placebo for the treatment of herpes labialis.
Study to Compare Efficacy of Topical ARYS-01 (Sorivudine) Cream 3%, Oral Valaciclovir and Combination...
Herpes ZosterPostherpetic NeuralgiaA multi-center, randomized, 4-arm, placebo-controlled, double-blind efficacy study of ARYS-01 (sorivudine) cream 3%.
A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients
Herpes SimplexHIV Infections1 moreThe purpose of this study is to see if valacyclovir (Valtrex) is a safe and effective treatment for ano-genital HSV infections (herpes simplex virus infections of the anus and external genitals) in HIV-infected patients.